NCBI: 02-MAR-2017
Contents
⊟Summary[edit source | edit]
- organism: Staphylococcus aureus USA300_FPR3757
- locus tag: SAUSA300_RS13245 [old locus tag: SAUSA300_2393 ]
- pan locus tag?: SAUPAN006000000
- symbol: SAUSA300_RS13245
- pan gene symbol?: opuCA
- synonym:
- product: glycine/betaine ABC transporter ATP-binding protein
⊟Genome View[edit source | edit]
⊟Gene[edit source | edit]
⊟General[edit source | edit]
- type: CDS
- locus tag: SAUSA300_RS13245 [old locus tag: SAUSA300_2393 ]
- symbol: SAUSA300_RS13245
- product: glycine/betaine ABC transporter ATP-binding protein
- replicon: chromosome
- strand: -
- coordinates: 2575903..2577129
- length: 1227
- essential: unknown
⊟Accession numbers[edit source | edit]
- Location: NC_007793 (2575903..2577129) NCBI
- MicrobesOnline:
⊟Phenotype[edit source | edit]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit source | edit]
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1201ATGTTAAGTATTAAGCATTTAACGAAAATTTATTCTGGTAATAAAAAGGCAGTAGATGAC
ATCTCTTTAGATATTCAATCTGGGGAATTTATCGCATTTATTGGAACCAGTGGAAGTGGC
AAAACGACTGCTTTAAGAATGATAAACCGTATGATTGAAGCGACAGAAGGACAAATTGAA
ATTGATGGTAAAGATGTTCGGAGTATGAATCCTGTCGAATTGCGTAGAAATATTGGCTAT
GTTATTCAACAAATTGGCTTAATGCCTCATATGACGATTAAAGAGAATATTGTGTTGGTA
CCCAAATTGTTGAAATGGACTAAAGAGGAAAAGGATAAACGTGCAAAGGAATTAATTAAA
CTTGTGGATTTACCGGAGTCATTTTTAGAGCGTTATCCAGCAGAAATATCAGGTGGGCAA
CAACAACGTATCGGTGTTGTAAGAGCACTTGCGGCCGAACAAGATATTATTTTAATGGAT
GAACCTTTTGGTGCATTGGATCCTATTACGAGAGATACGTTACAAGATTTAGTTAAAACG
TTACAACGAAAATTAGGCAAGACGTTTATCTTTGTAACACATGATATGGATGAAGCGATT
AAATTAGCAGACAAAATTTGTATTATGTCAGAAGGTAAGGTGGTGCAATTTGATACGCCA
GACAATATTTTAAGACATCCCGCAAATGATTTTGTACGTGATTTTATAGGACAAAATAGA
CTGATTCAAGACCGTCCCAATGACAAGACTGTAGAAGGTGTAATGATTAAACCAATCACG
ATACAAGCAGAAGCAACACTGAATGACGCCGTTCATATTATGAGACAAAAACGTGTTGAT
GCTATTTTTGTAGTAGATAGTAATAACCATTTACTAGGTTTCTTAGACATTGAAGATATA
AATCAGGGTATACGTGGACACAAAAGTTTACGAGACACCATGCAACAACATATTTATACC
GTTCAAATTGATTCTAAATTACAAGATTCTGTACGTACGATTTTAAAAAGAAACGTTAGG
AATGTACCTGTCGTAGATGATCAACAGCGTTTAGTAGGACTGATTACGCGTGCCAATGTT
GTTGATATTGTATATGACACGATTTGGGGCGATAGTGAGGATACAGTGCAAACAGAACAT
GTGGGGGAAGACACTGCGTCCTCAAAAGTGCATGAGCAACACACTACTAATGTCAAAGTA
CGTGACATAGGAGATGATAAATCATGA60
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⊟Protein[edit source | edit]
⊟General[edit source | edit]
- locus tag: SAUSA300_RS13245 [old locus tag: SAUSA300_2393 ]
- symbol: SAUSA300_RS13245
- description: glycine/betaine ABC transporter ATP-binding protein
- length: 408
- theoretical pI: 6.15286
- theoretical MW: 46143.6
- GRAVY: -0.339706
⊟Function[edit source | edit]
- reaction: EC 3.6.3.32? ExPASyQuaternary-amine-transporting ATPaseATP + H2O + quaternary amine(Out) = ADP + phosphate + quaternary amine(In)
- TIGRFAM: Transport and binding proteinsAmino acids, peptides and aminesglycine betaine/L-proline transport ATP binding subunit (TIGR01186; HMM-score: 455.3)Transport and binding proteinsAmino acids, peptides and aminesputative 2-aminoethylphosphonate ABC transporter, ATP-binding protein (TIGR03265; HMM-score: 245.5)Transport and binding proteinsAmino acids, peptides and aminescholine ABC transporter, ATP-binding protein (TIGR03415; HMM-score: 243.4)Transport and binding proteinsAnionssulfate ABC transporter, ATP-binding protein (TIGR00968; EC 3.6.3.25; HMM-score: 230.5)Transport and binding proteinsAmino acids, peptides and aminespolyamine ABC transporter, ATP-binding protein (TIGR01187; EC 3.6.3.31; HMM-score: 223.3)2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT (TIGR03258; HMM-score: 200.6)Transport and binding proteinsAnionsphosphate ABC transporter, ATP-binding protein (TIGR00972; EC 3.6.3.27; HMM-score: 189.9)Transport and binding proteinsUnknown substrateenergy-coupling factor transporter ATPase (TIGR04521; EC 3.6.3.-; HMM-score: 188.7)Transport and binding proteinsOtherdaunorubicin resistance ABC transporter, ATP-binding protein (TIGR01188; HMM-score: 175.9)Transport and binding proteinsAnionsphosphonate ABC transporter, ATP-binding protein (TIGR02315; EC 3.6.3.28; HMM-score: 175.3)D-methionine ABC transporter, ATP-binding protein (TIGR02314; EC 3.6.3.-; HMM-score: 169.1)Transport and binding proteinsUnknown substrateenergy-coupling factor transporter ATPase (TIGR04520; EC 3.6.3.-; HMM-score: 163.7)Cellular processesCell divisioncell division ATP-binding protein FtsE (TIGR02673; HMM-score: 157.9)Cellular processesToxin production and resistanceputative bacteriocin export ABC transporter, lactococcin 972 group (TIGR03608; HMM-score: 154.2)Transport and binding proteinsUnknown substrateputative bacteriocin export ABC transporter, lactococcin 972 group (TIGR03608; HMM-score: 154.2)ectoine/hydroxyectoine ABC transporter, ATP-binding protein EhuA (TIGR03005; HMM-score: 153.4)Transport and binding proteinsAnionsnitrate ABC transporter, ATP-binding proteins C and D (TIGR01184; HMM-score: 153.2)Transport and binding proteinsOthernitrate ABC transporter, ATP-binding proteins C and D (TIGR01184; HMM-score: 153.2)Transport and binding proteinsAnionsmolybdate ABC transporter, ATP-binding protein (TIGR02142; EC 3.6.3.29; HMM-score: 150.1)Transport and binding proteinsCations and iron carrying compoundsnickel import ATP-binding protein NikE (TIGR02769; EC 3.6.3.24; HMM-score: 148)ABC exporter ATP-binding subunit, DevA family (TIGR02982; HMM-score: 146)Cellular processesPathogenesistype I secretion system ATPase (TIGR03375; HMM-score: 145.9)Protein fateProtein and peptide secretion and traffickingtype I secretion system ATPase (TIGR03375; HMM-score: 145.9)Cell envelopeBiosynthesis and degradation of surface polysaccharides and lipopolysaccharidesLPS export ABC transporter ATP-binding protein (TIGR04406; HMM-score: 144.7)Transport and binding proteinsOtherLPS export ABC transporter ATP-binding protein (TIGR04406; HMM-score: 144.7)Transport and binding proteinsOtherthiamine ABC transporter, ATP-binding protein (TIGR01277; EC 3.6.3.-; HMM-score: 144.4)Protein fateProtein and peptide secretion and traffickinglipoprotein releasing system, ATP-binding protein (TIGR02211; EC 3.6.3.-; HMM-score: 144.2)Transport and binding proteinsCarbohydrates, organic alcohols, and acidsABC transporter, ATP-binding subunit, PQQ-dependent alcohol dehydrogenase system (TIGR03864; HMM-score: 137.6)thiol reductant ABC exporter, CydD subunit (TIGR02857; HMM-score: 135.1)Transport and binding proteinsAmino acids, peptides and aminesurea ABC transporter, ATP-binding protein UrtE (TIGR03410; HMM-score: 133.7)Energy metabolismMethanogenesismethyl coenzyme M reductase system, component A2 (TIGR03269; HMM-score: 132.3)Transport and binding proteinsCations and iron carrying compoundsnickel import ATP-binding protein NikD (TIGR02770; HMM-score: 130.1)gliding motility-associated ABC transporter ATP-binding subunit GldA (TIGR03522; HMM-score: 125.6)Protein fateProtein and peptide secretion and traffickingtype I secretion system ATPase (TIGR01842; HMM-score: 124.2)ABC transporter, permease/ATP-binding protein (TIGR02204; HMM-score: 122.1)Cell envelopeBiosynthesis and degradation of surface polysaccharides and lipopolysaccharideslipid A export permease/ATP-binding protein MsbA (TIGR02203; HMM-score: 121.4)Transport and binding proteinsOtherlipid A export permease/ATP-binding protein MsbA (TIGR02203; HMM-score: 121.4)Cellular processesBiosynthesis of natural productsNHLM bacteriocin system ABC transporter, ATP-binding protein (TIGR03797; HMM-score: 120.9)Transport and binding proteinsAmino acids, peptides and aminesNHLM bacteriocin system ABC transporter, ATP-binding protein (TIGR03797; HMM-score: 120.9)Protein fateProtein and peptide secretion and traffickingtype I secretion system ATPase (TIGR01846; HMM-score: 117.4)lantibiotic protection ABC transporter, ATP-binding subunit (TIGR03740; HMM-score: 113.8)Cellular processesBiosynthesis of natural productsNHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein (TIGR03796; HMM-score: 113.2)Transport and binding proteinsAmino acids, peptides and aminesNHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein (TIGR03796; HMM-score: 113.2)thiol reductant ABC exporter, CydC subunit (TIGR02868; HMM-score: 111.8)Protein fateProtein and peptide secretion and traffickingABC-type bacteriocin transporter (TIGR01193; HMM-score: 108.8)Protein fateProtein modification and repairABC-type bacteriocin transporter (TIGR01193; HMM-score: 108.8)Transport and binding proteinsOtherABC-type bacteriocin transporter (TIGR01193; HMM-score: 108.8)proposed F420-0 ABC transporter, ATP-binding protein (TIGR03873; HMM-score: 106.5)Cellular processesOthernodulation ABC transporter NodI (TIGR01288; HMM-score: 104.7)Transport and binding proteinsOthernodulation ABC transporter NodI (TIGR01288; HMM-score: 104.7)Transport and binding proteinsUnknown substrateanchored repeat-type ABC transporter, ATP-binding subunit (TIGR03771; HMM-score: 103.9)Transport and binding proteinsCations and iron carrying compoundscobalt ABC transporter, ATP-binding protein (TIGR01166; HMM-score: 100.8)phosphonate C-P lyase system protein PhnL (TIGR02324; HMM-score: 99.4)Transport and binding proteinsAmino acids, peptides and aminesurea ABC transporter, ATP-binding protein UrtD (TIGR03411; HMM-score: 97.6)Transport and binding proteinsCarbohydrates, organic alcohols, and acidsD-xylose ABC transporter, ATP-binding protein (TIGR02633; EC 3.6.3.17; HMM-score: 96)Transport and binding proteinsCarbohydrates, organic alcohols, and acidsglucan exporter ATP-binding protein (TIGR01192; EC 3.6.3.42; HMM-score: 94)Transport and binding proteinsOtherrim ABC transporter (TIGR01257; HMM-score: 92.8)Transport and binding proteinsOtherantigen peptide transporter 2 (TIGR00958; HMM-score: 90.4)Protein fateProtein and peptide secretion and traffickingheme ABC exporter, ATP-binding protein CcmA (TIGR01189; EC 3.6.3.41; HMM-score: 88.6)Transport and binding proteinsOtherheme ABC exporter, ATP-binding protein CcmA (TIGR01189; EC 3.6.3.41; HMM-score: 88.6)Transport and binding proteinsOtherpigment precursor permease (TIGR00955; HMM-score: 83.7)Central intermediary metabolismPhosphorus compoundsphosphonate C-P lyase system protein PhnK (TIGR02323; HMM-score: 80.7)Transport and binding proteinsAnionscystic fibrosis transmembrane conductor regulator (CFTR) (TIGR01271; EC 3.6.3.49; HMM-score: 75)Biosynthesis of cofactors, prosthetic groups, and carriersOtherFeS assembly ATPase SufC (TIGR01978; HMM-score: 62.6)Transport and binding proteinsOthermulti drug resistance-associated protein (MRP) (TIGR00957; HMM-score: 60.4)Transport and binding proteinsAmino acids, peptides and aminescyclic peptide transporter (TIGR01194; HMM-score: 57)Transport and binding proteinsOthercyclic peptide transporter (TIGR01194; HMM-score: 57)ATP-binding cassette protein, ChvD family (TIGR03719; HMM-score: 53.6)Transport and binding proteinsOtherpleiotropic drug resistance family protein (TIGR00956; HMM-score: 48.8)Purines, pyrimidines, nucleosides, and nucleotidesPurine ribonucleotide biosynthesisinosine-5'-monophosphate dehydrogenase (TIGR01302; EC 1.1.1.205; HMM-score: 45.7)DNA metabolismDNA replication, recombination, and repairexcinuclease ABC subunit A (TIGR00630; EC 3.1.25.-; HMM-score: 40.5)Energy metabolismSugarssugar isomerase, KpsF/GutQ family (TIGR00393; HMM-score: 37.4)Transport and binding proteinsCations and iron carrying compoundsmagnesium transporter (TIGR00400; HMM-score: 35.3)Unknown functionGeneralIMP dehydrogenase family protein (TIGR01303; HMM-score: 26.1)Amino acid biosynthesisSerine familycystathionine beta-synthase (TIGR01137; EC 4.2.1.22; HMM-score: 24.2)Transport and binding proteinsCarbohydrates, organic alcohols, and acidsperoxysomal long chain fatty acyl transporter (TIGR00954; HMM-score: 18.3)Purines, pyrimidines, nucleosides, and nucleotidesNucleotide and nucleoside interconversionsdTMP kinase (TIGR00041; EC 2.7.4.9; HMM-score: 13.4)Central intermediary metabolismSulfur metabolismadenylyl-sulfate kinase (TIGR00455; EC 2.7.1.25; HMM-score: 13.1)
- TheSEED:
- PFAM: P-loop_NTPase (CL0023) ABC_tran; ABC transporter (PF00005; HMM-score: 113.3)no clan definedCBS; CBS domain (PF00571; HMM-score: 64.3)P-loop_NTPase (CL0023) AAA_21; AAA domain, putative AbiEii toxin, Type IV TA system (PF13304; HMM-score: 25.9)AAA_15; AAA ATPase domain (PF13175; HMM-score: 21.7)Zeta_toxin; Zeta toxin (PF06414; HMM-score: 19.3)AAA_16; AAA ATPase domain (PF13191; HMM-score: 18.4)AAA_22; AAA domain (PF13401; HMM-score: 18)NTPase_1; NTPase (PF03266; HMM-score: 17.6)AAA_30; AAA domain (PF13604; HMM-score: 17.2)AAA; ATPase family associated with various cellular activities (AAA) (PF00004; HMM-score: 16.7)AAA_29; P-loop containing region of AAA domain (PF13555; HMM-score: 15.4)AAA_18; AAA domain (PF13238; HMM-score: 15.2)AAA_28; AAA domain (PF13521; HMM-score: 14.9)RsgA_GTPase; RsgA GTPase (PF03193; HMM-score: 14.8)
⊟Structure, modifications & interactions[edit source | edit]
- domains:
- modifications:
- cofactors:
- effectors:
- protein partners:
⊟Localization[edit source | edit]
- PSORTb: Cytoplasmic Membrane
- Cytoplasmic Score: 1.05
- Cytoplasmic Membrane Score: 8.78
- Cellwall Score: 0.08
- Extracellular Score: 0.09
- Internal Helices: 0
- LocateP:
- SignalP: no predicted signal peptide
- Ymax: 0.142
- Ymax_pos: 11
- Cmax: 0.151
- Cmax_pos: 47
- Smax: 0.267
- Smax_pos: 2
- Smean: 0.192
- D: 0.162
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit source | edit]
⊟Protein sequence[edit source | edit]
- MLSIKHLTKIYSGNKKAVDDISLDIQSGEFIAFIGTSGSGKTTALRMINRMIEATEGQIEIDGKDVRSMNPVELRRNIGYVIQQIGLMPHMTIKENIVLVPKLLKWTKEEKDKRAKELIKLVDLPESFLERYPAEISGGQQQRIGVVRALAAEQDIILMDEPFGALDPITRDTLQDLVKTLQRKLGKTFIFVTHDMDEAIKLADKICIMSEGKVVQFDTPDNILRHPANDFVRDFIGQNRLIQDRPNDKTVEGVMIKPITIQAEATLNDAVHIMRQKRVDAIFVVDSNNHLLGFLDIEDINQGIRGHKSLRDTMQQHIYTVQIDSKLQDSVRTILKRNVRNVPVVDDQQRLVGLITRANVVDIVYDTIWGDSEDTVQTEHVGEDTASSKVHEQHTTNVKVRDIGDDKS
⊟Experimental data[edit source | edit]
- experimentally validated: no data available
⊟Expression & Regulation[edit source | edit]
⊟Operon[edit source | edit]
- SAUSA300_RS13245 no polycistronic organisation predicted
⊟Regulation[edit source | edit]
- sigma factor:
- regulator:
⊟Transcription pattern[edit source | edit]
- S.aureus Expression Data Browser: no data available
⊟Protein synthesis (provided by Aureolib)[edit source | edit]
- Aureolib: no data available
⊟Protein stability[edit source | edit]
- half-life: no data available
⊟Biological Material[edit source | edit]
⊟Mutants[edit source | edit]
⊟Expression vector[edit source | edit]
⊟lacZ fusion[edit source | edit]
⊟GFP fusion[edit source | edit]
⊟two-hybrid system[edit source | edit]
⊟FLAG-tag construct[edit source | edit]
⊟Antibody[edit source | edit]
⊟Other Information[edit source | edit]
You are kindly invited to share additional interesting facts.
⊟Literature[edit source | edit]
⊟References[edit source | edit]
⊟Relevant publications[edit source | edit]