PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 02-MAR-2017

⊟Summary

• organism: Staphylococcus aureus N315
• locus tag: SA_RS01910 [old locus tag: SA0333 ]
• pan locus tag^?: SAUPAN001884000
• symbol: SA_RS01910
• pan gene symbol^?: fepC
• synonym:
• product: iron permease FTR1 family protein

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SA_RS01910 [old locus tag: SA0333 ]
• symbol: SA_RS01910
• product: iron permease FTR1 family protein
• replicon: chromosome
• strand: +
• coordinates: 391055..392737
• length: 1683
• essential: no DEG other strains

⊟Accession numbers

• Location: NC_002745 (391055..392737) NCBI
• BioCyc: G1G21-362 BioCyc
• MicrobesOnline: see SA0333

⊟Phenotype

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⊟DNA sequence

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  ATGCTAATAACTGCTGCTATGGTGTGTAGCTTTGGGTTACTGAAAAGTCAGGCAGCAGAA
  CAACAAAGTATTAGTGATGTATATAGTGTGATAACGGATGCGAAATCTGCACTTTCTAAT
  AATTCGATATCGAATGACAATAAGCAGAAAGCAATTGAGCAAGTGGTAAGTGCAGTTAAG
  AAATTATCGCTTGAAGATAATAGTGAAGGTAATGCTGTCAAATCAGATGTGAGAAAGCTT
  GAAGATGCAAAAGCGAATGATAATCAAAAAGATACACTTTCGCAATTAACGAAGTCATTA
  ATTGCTTATGAAGAGAAATTGGCTAGTAAAGATGCGGGTTCTAAAATTAAACTATTGCAA
  CAGCAAGTCGATGCCAAAGATGCTGCGATGACAAAAGCGATTAAAGATAAAAATAAAGCG
  GAATTAGAATCTTTGAACAATAGTTTGAATCAGATTTGGACAAGTAATGAAACAGTGATT
  CGCAATTATGACGCAAATCAATATGGACAAATTGAAGTCGCATTATTACAACTTAGAATT
  GCAATTCATAAGTCACCATTAGATACGGCAAAAGTGTCACATGCTTGGACAACTTTTAAA
  TCAAATATTGATCATGTCGATAAAAAAAGTGATACGTCTGCAAATGATCAATACCATGTA
  TCACAATTAAATGATGCGTTAGAGAAGGCGATTAAAGCTATCGACGACAATCAATTGTCG
  GATGCTGATGCTGCGCTTACACATTTTATAGAAATTTGGCCGTATGTTGAAGGTCAAATT
  CAAACTAAAGACGGGGCTTTGTATACGAAAATTGAAGATAAAATACCATATTATCAAAGT
  GTATTAGACGAACATAATAAATCGCATGTCAAAGATGGTTTAGTAGATATAAACAATCAA
  ATTAAAGAGGTTGTTGGCCATAGTTATAGCTTTGTCGATGTGATGATTATCTTTTTACGT
  GAAGGACTAGAAGTGTTATTAATTGTAATGACATTGACTACCATGACGCGTAAAGTCAAA
  GATAATAAGGGGACTGCAAGTGTGATTGGTGGTGCAATTGCCGGACTTGTACTGAGTATT
  ATCTTAGCAATTACGTTTGTAGAAACTTTAGGGAATAGTGGCATTCTTCGTGAAAGTATG
  GAAGCGGGATTAGGTATCGTTGCGGTCATATTAATGTTTATCGTTGGTGTTTGGATGCAC
  AAACGTTCAAATGCGAAACGCTGGAATGATATGATTAAAAATATGTATGCCAATGCGATT
  AGTAATGGTAATTTGGTATTGTTAGCGACGATTGGTTTAATATCTGTGTTGCGTGAAGGT
  GTTGAGGTTATCATTTTCTATATGGGGATGATAGGTGAGCTAGCGACAAAAGATTTTATT
  ATTGGTATTGCCTTGGCCATAGTGATATTAATTGTCTTTGCGGTATTATTTAGATTTATC
  GTCAGATTGATACCTATATTCTATATATTTAGAGTATTGTCGATCTTTATTTTTATTATG
  GGATTCAAAATGCTTGGCGTAAGTATTCAAAAGTTACAATTATTAGGTGCGATGCCAAGA
  CATGTTATTGAAGGATTCCCAACGATTAACTGGTTGGGCTTCTATCCAAGTTATGAACCA
  TTGATAGCACAAGCTGCTTATATTATGGTAGTTGCTATCTTAATCTTTAAATTTAAAAAA
  TAA
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  1683
  

⊟Protein

⊟General

• locus tag: SA_RS01910 [old locus tag: SA0333 ]
• symbol: SA_RS01910
• description: iron permease FTR1 family protein
• length: 560
• theoretical pI: 7.3852
• theoretical MW: 62100.9
• GRAVY: 0.187143

⊟Function

• TIGRFAM:
  Unknown function General FTR1 family protein (TIGR00145; HMM-score: 89.4)
• TheSEED: see SA0333
• PFAM:
  MFS (CL0015) FTR1; Iron permease FTR1 family (PF03239; HMM-score: 72.5)
  and 5 more
  no clan defined Tim17; Tim17/Tim22/Tim23/Pmp24 family (PF02466; HMM-score: 15.6)
  MNHE; Na+/H+ ion antiporter subunit (PF01899; HMM-score: 10.4)
  RecG_N; RecG N-terminal helical domain (PF17190; HMM-score: 9.8)
  DUF1539; Domain of Unknown Function (DUF1539) (PF07560; HMM-score: 8.2)
  CCDC84; Coiled coil protein 84 (PF14968; HMM-score: 6.8)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic Membrane
  • Cytoplasmic Score: 0
  • Cytoplasmic Membrane Score: 10
  • Cellwall Score: 0
  • Extracellular Score: 0
  • Internal Helices: 6
• LocateP:
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.469506
  • TAT(Tat/SPI): 0.005896
  • LIPO(Sec/SPII): 0.030291
• predicted transmembrane helices (TMHMM): 6

⊟Accession numbers

• GI: see SA0333
• RefSeq: WP_001822764 NCBI
• UniProt: see SA0333

⊟Protein sequence

• MLITAAMVCSFGLLKSQAAEQQSISDVYSVITDAKSALSNNSISNDNKQKAIEQVVSAVKKLSLEDNSEGNAVKSDVRKLEDAKANDNQKDTLSQLTKSLIAYEEKLASKDAGSKIKLLQQQVDAKDAAMTKAIKDKNKAELESLNNSLNQIWTSNETVIRNYDANQYGQIEVALLQLRIAIHKSPLDTAKVSHAWTTFKSNIDHVDKKSDTSANDQYHVSQLNDALEKAIKAIDDNQLSDADAALTHFIEIWPYVEGQIQTKDGALYTKIEDKIPYYQSVLDEHNKSHVKDGLVDINNQIKEVVGHSYSFVDVMIIFLREGLEVLLIVMTLTTMTRKVKDNKGTASVIGGAIAGLVLSIILAITFVETLGNSGILRESMEAGLGIVAVILMFIVGVWMHKRSNAKRWNDMIKNMYANAISNGNLVLLATIGLISVLREGVEVIIFYMGMIGELATKDFIIGIALAIVILIVFAVLFRFIVRLIPIFYIFRVLSIFIFIMGFKMLGVSIQKLQLLGAMPRHVIEGFPTINWLGFYPSYEPLIAQAAYIMVVAILIFKFKK

⊟Experimental data

• experimentally validated:
• protein localization: data available for COL
• quantitative data / protein copy number per cell:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator: Fur* see SA0333

⊟Transcription pattern

• S.aureus Expression Data Browser: data available for NCTC8325

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications