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NCBI: 02-MAR-2017

Summary[edit source | edit]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS04230 [old locus tag: SA0743 ]
  • pan locus tag?: SAUPAN002791000
  • symbol: SA_RS04230
  • pan gene symbol?: vwb
  • synonym:
  • product: coagulase

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SA_RS04230 [old locus tag: SA0743 ]
  • symbol: SA_RS04230
  • product: coagulase
  • replicon: chromosome
  • strand: +
  • coordinates: 851674..853176
  • length: 1503
  • essential: unknown

Accession numbers[edit source | edit]

  • Location: NC_002745 (851674..853176) NCBI
  • MicrobesOnline:

Phenotype[edit source | edit]

Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    TTGAAAAATAAATTGCTAGTTTTATCATTGGGAGCATTATGTGTATCACAAATTTGGGAA
    AGTAATCATGCGAGTGCAGTGGTTTCTGGGGAGAAGAATCCATATGTATCAAAAGCTTTA
    GAATTGAAAGATAAAAGTAATAAATCCAATTCTTACGAAAATTATAGAGATAGTTTAGAA
    AGTTTGATTTCATCATTATCTTTTGCTGATTATGAAAAATATGAAGAGCCAGAATATGAA
    AAGGCTGTAAAAAAATATCAACAAAAATTTATGGCTGAAGATGATGCATTAAAAAATTTT
    TTAAATGAAGAAAAGAAGATAAAAAATGCAGATATTAGCAGAAAATCGAATAATTTATTA
    GGTTTAACACATGAAAGATATTCTTATATTTTTGATACATTAAAGAAAAATAAACAAGAG
    TTTTTAAAAGATATTGAAGAAATACAACTGAAAAATAGTGATTTAAAGGACTTTAACAAT
    ACAGAGCAACATAATGCCGACGTAGAAATAAACAATTTAGAAAATAAAGTATTAATGGTA
    GGGTATACATTCTATAATACAAATAAGGACGAAGTTGAAGAATTATATAGTGAGTTAGAT
    TTGATTGTTGGAGAAGTTCAAGATAAGTCGGATAAAAAAAGAGCAGTAAATCAAAGGATG
    TTAAATAGAAAAAAAGAGGATTTAGAATTTATTATAGATAAATTTTTTAAAAAAATTCAA
    CAAGAACGTCCAGAGAGTATACCAGCATTAACTAGTGAAAAAAATCATAATCAGACTATG
    GCATTAAAGTTAAAAGCAGATACAGAAGCTGCTAAAAATGACGTATCAAAAAGAAGTAAA
    AGAAGTTTAAATACTCAAAATAATAAATCTACAACACAAGAAATTTCTGAAGAACAAAAA
    GCTGAATATCAAAGAAAGTCAGAGGCATTAAAAGAAAGATTTATAAACAGACAAAAATCT
    AAAAATGAGTCTGTGGTTTCACTAATCGATGACGAAGACGACAACGAAAACGACAGGCAA
    CTTGTGGTTTCTGCGCCATCAAAGAAACCAACAACACCGACTACATATACTGAAACAACG
    ACTCAGGTACCAATGCCTACAGTTGAGCGTCAAACTCAGCAACAAATCGTTTACAAAACA
    CCAAAACCATTAGCTGGATTAAATGGTGAAAGTCATGATTTCACAACAACGCATCAATCA
    CCAACAACTTCAAATCATACGCATAATAATGTTGTTGAATTTGAAGAAACGTCTGCTTTA
    CCTGGTAGAAAATCAGGATCACTGGTTGGTATAAGTCAAATTGATTCTTCTCATCTAACT
    GAACGTGAGAAGCGTGTAATCAAGCGTGAACACGTTAGAGAAGCTCAAAAGTTAGTTGAT
    AATTATAAAGATACACATAGTTATAAAGACCGATTAAATGCACAACAAAAAGTAAATACT
    TTAAGTGAAGGTCATCAAAAACGTTTTAATAAACAAATCAATAAAGTATACAATGGCAAA
    TAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1503

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SA_RS04230 [old locus tag: SA0743 ]
  • symbol: SA_RS04230
  • description: coagulase
  • length: 500
  • theoretical pI: 8.2998
  • theoretical MW: 57792
  • GRAVY: -1.0796

Function[edit source | edit]

  • TIGRFAM:
  • TheSEED:
  • PFAM:
    no clan definedCoagulase; Staphylococcus aureus coagulase (PF08764; HMM-score: 63.6)
    and 2 more
    YopE_N; YopE, N terminal (PF09020; HMM-score: 13.6)
    Oxa1 (CL0376) DUF106; Integral membrane protein DUF106 (PF01956; HMM-score: 8.4)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Extracellular
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0.09
    • Cellwall Score: 0.18
    • Extracellular Score: 9.73
    • Internal Helices: 0
  • LocateP:
  • SignalP: Signal peptide length 27 aa
    • Ymax: 0.481
    • Ymax_pos: 27
    • Cmax: 0.303
    • Cmax_pos: 27
    • Smax: 0.922
    • Smax_pos: 18
    • Smean: 0.737
    • D: 0.581
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

  • GI: 446714371 NCBI
  • RefSeq: WP_000791702 NCBI
  • UniProt:

Protein sequence[edit source | edit]

  • MKNKLLVLSLGALCVSQIWESNHASAVVSGEKNPYVSKALELKDKSNKSNSYENYRDSLESLISSLSFADYEKYEEPEYEKAVKKYQQKFMAEDDALKNFLNEEKKIKNADISRKSNNLLGLTHERYSYIFDTLKKNKQEFLKDIEEIQLKNSDLKDFNNTEQHNADVEINNLENKVLMVGYTFYNTNKDEVEELYSELDLIVGEVQDKSDKKRAVNQRMLNRKKEDLEFIIDKFFKKIQQERPESIPALTSEKNHNQTMALKLKADTEAAKNDVSKRSKRSLNTQNNKSTTQEISEEQKAEYQRKSEALKERFINRQKSKNESVVSLIDDEDDNENDRQLVVSAPSKKPTTPTTYTETTTQVPMPTVERQTQQQIVYKTPKPLAGLNGESHDFTTTHQSPTTSNHTHNNVVEFEETSALPGRKSGSLVGISQIDSSHLTEREKRVIKREHVREAQKLVDNYKDTHSYKDRLNAQQKVNTLSEGHQKRFNKQINKVYNGK

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • SA_RS04230 no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]