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NCBI: 02-MAR-2017

Summary[edit source | edit]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS08845 [old locus tag: SA1568 ]
  • pan locus tag?: SAUPAN004414000
  • symbol: SA_RS08845
  • pan gene symbol?:
  • synonym:
  • product: MBL fold metallo-hydrolase

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SA_RS08845 [old locus tag: SA1568 ]
  • symbol: SA_RS08845
  • product: MBL fold metallo-hydrolase
  • replicon: chromosome
  • strand: -
  • coordinates: 1798244..1799086
  • length: 843
  • essential: unknown

Accession numbers[edit source | edit]

  • Location: NC_002745 (1798244..1799086) NCBI
  • MicrobesOnline:

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    ATGAAGATCGGGGATATATCTATTCATTATCTAAATGGTGGCAATACAAAAATGGATGGC
    GGTGCAATGTTTGGTGTTGTTCCGAAGCCGTTGTGGTCAAAGCAATACAATGCAAATGAA
    CGAAATCAAATCAATTTACCGACACATCCAATTTTGATTCAAACGGCTCAATATAATTTG
    ATTATAGATGCGGGTATTGGTAATGGTAAATTATCTGAAAAGCAATTACGTAATTTTGGA
    GTAGATGAAGAAAGTCATATAATTGCTGATTTGGCAAATTATAATTTAACGCCAAAGGAT
    ATTGATTATGTGCTAATGACACATATGCATTTTGATCATGCTGCCGGTTTGACTGATCAA
    GCGGGACATGCAATTTTTGAAAATGCGATTCATGTTGTGCAACAAGATGAGTGGCATGAG
    TTTATTGCACCTAATATAAGAAGTAAATCAACTTACTGGGATAAGAATAAAGGCGATTAT
    AGTAACAAGTTGATTTTATTCGAAAAACATTTTGAACCGGTTCCGGGTATCAAGATGCAA
    CATAGTGGAGGTCATAGCTTTGGCCACACGATTATTACGATTGAAAGTCAAGGAGATAAA
    GCAGTTCATATGGGTGATATATTCCCAACTACTGCACATAAAAATCCTCTATGGGTAACG
    GCATATGATGATTATCCTATGCAATCGATTCGTGAAAAAGAACGCATGATACCATATTTT
    ATTCAGCAACAATATTGGTTCTTGTTTTATCATGATGAAAACTACTTTGCTGTAAAATAC
    AGCGATGATGGTGAAAACATAGATGCATATATTTTACGTGAAACATTAGTTGATAATAAC
    TAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    843

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SA_RS08845 [old locus tag: SA1568 ]
  • symbol: SA_RS08845
  • description: MBL fold metallo-hydrolase
  • length: 280
  • theoretical pI: 5.93292
  • theoretical MW: 32173.9
  • GRAVY: -0.510714

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    Genetic information processingTranscriptionRNA processingribonuclease Z (TIGR02651; EC 3.1.26.11; HMM-score: 19.9)
    Unknown functionEnzymes of unknown specificityquinoprotein relay system zinc metallohydrolase 2 (TIGR04559; EC 3.-.-.-; HMM-score: 17)
    phosphonate metabolism protein PhnP (TIGR03307; HMM-score: 12.8)
    arCOG00543 universal archaeal KH-domain/beta-lactamase-domain protein (TIGR03675; HMM-score: 12.8)
  • TheSEED:
  • PFAM:
    Metallo-HOrase (CL0381) Lactamase_B; Metallo-beta-lactamase superfamily (PF00753; HMM-score: 55.9)
    Lactamase_B_3; Beta-lactamase superfamily domain (PF13483; HMM-score: 22.6)
    Lactamase_B_2; Beta-lactamase superfamily domain (PF12706; HMM-score: 22.3)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • Ymax: 0.135
    • Ymax_pos: 39
    • Cmax: 0.132
    • Cmax_pos: 23
    • Smax: 0.231
    • Smax_pos: 31
    • Smean: 0.124
    • D: 0.131
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

  • GI: 446612236 NCBI
  • RefSeq: WP_000689582 NCBI
  • UniProt:

Protein sequence[edit source | edit]

  • MKIGDISIHYLNGGNTKMDGGAMFGVVPKPLWSKQYNANERNQINLPTHPILIQTAQYNLIIDAGIGNGKLSEKQLRNFGVDEESHIIADLANYNLTPKDIDYVLMTHMHFDHAAGLTDQAGHAIFENAIHVVQQDEWHEFIAPNIRSKSTYWDKNKGDYSNKLILFEKHFEPVPGIKMQHSGGHSFGHTIITIESQGDKAVHMGDIFPTTAHKNPLWVTAYDDYPMQSIREKERMIPYFIQQQYWFLFYHDENYFAVKYSDDGENIDAYILRETLVDNN

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • SA_RS08845 no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]