NCBI: 02-MAR-2017

⊟Summary

• organism: Staphylococcus aureus N315
• locus tag: SA_RS09705 [old locus tag: SA1691 ]
• pan locus tag^?: SAUPAN004857000
• symbol: SA_RS09705
• pan gene symbol^?: sgtB
• synonym:
• product: monofunctional glycosyltransferase

⊟Gene

⊟General

• type: CDS
• locus tag: SA_RS09705 [old locus tag: SA1691 ]
• symbol: SA_RS09705
• product: monofunctional glycosyltransferase
• replicon: chromosome
• strand: -
• coordinates: 1938571..1939380
• length: 810
• essential: unknown

⊟Accession numbers

• Location: NC_002745 (1938571..1939380) NCBI
• MicrobesOnline:

⊟Phenotype

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⊟DNA sequence

• 1
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  ATGAAAAGAAGCGATAGGTACTCAAACTCAAATGAACATTTTGAGCATATGAAACACGAA
  CCTCACTATAATACGTATTATCAACCAGTTGGCAAACCGCCGAAAAAGAAAAAAAGTAAA
  CGAATACTATTAAAAATATTATTAACCATTCTAATCATTATCGCATTGTTTATTGGTATC
  ATGTATTTTTTATCTACACGCGATAATGTGGATGAACTAAGAAAAATTGAAAATAAAAGT
  AGTTTTGTGTCAGCTGATAACATGCCAGAGTATGTTAAAGGTGCCTTTATTTCAATGGAA
  GATGAACGATTCTACAATCATCATGGATTCGATTTGAAAGGTACAACTAGAGCTTTATTT
  TCAACGATTAGCGACAGAGATGTGCAAGGTGGTAGTACCATTACACAACAAGTTGTCAAA
  AATTATTTTTATGATAATGATCGTTCATTTACTAGAAAAGTAAAAGAATTATTTGTAGCT
  CATCGAGTTGAAAAACAATATAATAAGAACGAAATTTTAAGCTTTTATTTAAATAATATT
  TACTTTGGGGATAATCAATATACGCTTGAGGGCGCAGCAAACCATTACTTTGGAACAACC
  GTGAATAAAAATAGTACAACAATGTCTCACATAACAGTTTTACAAAGCGCTATTTTAGCT
  AGTAAAGTCAATGCACCTAGCGTATATAATATCAATAATATGTCAGAGAATTTTACGCAA
  CGTGTAAGCACGAACTTAGAAAAAATGAAGCAACAAAATTATATCAATGAAACACAATAT
  CAACAGGCTATGTCACAATTAAATCGTTAA
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⊟Protein

⊟General

• locus tag: SA_RS09705 [old locus tag: SA1691 ]
• symbol: SA_RS09705
• description: monofunctional glycosyltransferase
• length: 269
• theoretical pI: 9.82726
• theoretical MW: 31459.4
• GRAVY: -0.664312

⊟Function

• reaction:
  EC 2.4.1.129?  ExPASy
  Peptidoglycan glycosyltransferase(GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala))(n)-diphosphoundecaprenol + GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol = (GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala))(n+1)-diphosphoundecaprenol + undecaprenyl diphosphate
• TIGRFAM:
  Cell structureCell envelopeBiosynthesis and degradation of murein sacculus and peptidoglycanpenicillin-binding protein, 1A family (TIGR02074; HMM-score: 199.4)
  Cell structureCell envelopeBiosynthesis and degradation of murein sacculus and peptidoglycanpenicillin-binding protein 1B (TIGR02071; HMM-score: 131.8)
  Cell structureCell envelopeBiosynthesis and degradation of murein sacculus and peptidoglycanmonofunctional biosynthetic peptidoglycan transglycosylase (TIGR02070; EC 2.4.2.-; HMM-score: 127.2)
  Cell structureCell envelopeBiosynthesis and degradation of murein sacculus and peptidoglycanpenicillin-binding protein 1C (TIGR02073; HMM-score: 114.3)
  Cell structureCell envelopeBiosynthesis and degradation of surface polysaccharides and lipopolysaccharidesoligosaccharide repeat unit polymerase (TIGR04370; HMM-score: 14.2)
  YhgE/Pip N-terminal domain (TIGR03061; HMM-score: 13.3)
• TheSEED:
• PFAM:
  Lysozyme (CL0037) Transgly; Transglycosylase (PF00912; HMM-score: 186.5)
  no clan definedOrf78; Orf78 (ac78) (PF06024; HMM-score: 18.6)
  Sigma_reg_N; Sigma factor regulator N-terminal (PF13800; HMM-score: 9.2)

⊟Structure, modifications & interactions

• domains:
• modifications:
• cofactors:
• effectors:
• protein partners:

⊟Localization

• PSORTb: Cytoplasmic Membrane
  • Cytoplasmic Score: 0
  • Cytoplasmic Membrane Score: 10
  • Cellwall Score: 0
  • Extracellular Score: 0
  • Internal Helix: 1
• LocateP:
• SignalP: no predicted signal peptide
  • Ymax: 0.129
  • Ymax_pos: 47
  • Cmax: 0.104
  • Cmax_pos: 38
  • Smax: 0.213
  • Smax_pos: 39
  • Smean: 0.12
  • D: 0.126
• predicted transmembrane helices (TMHMM): 1

⊟Accession numbers

• GI: 446753124 NCBI
• RefSeq: WP_000830380 NCBI
• UniProt:

⊟Protein sequence

• MKRSDRYSNSNEHFEHMKHEPHYNTYYQPVGKPPKKKKSKRILLKILLTILIIIALFIGIMYFLSTRDNVDELRKIENKSSFVSADNMPEYVKGAFISMEDERFYNHHGFDLKGTTRALFSTISDRDVQGGSTITQQVVKNYFYDNDRSFTRKVKELFVAHRVEKQYNKNEILSFYLNNIYFGDNQYTLEGAANHYFGTTVNKNSTTMSHITVLQSAILASKVNAPSVYNINNMSENFTQRVSTNLEKMKQQNYINETQYQQAMSQLNR

⊟Experimental data

• experimentally validated: no data available

⊟Expression & Regulation

⊟Operon

• SA_RS09705 no polycistronic organisation predicted

⊟Regulation

• sigma factor:
• regulator:

⊟Transcription pattern

• S.aureus Expression Data Browser: no data available

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊟Other Information

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