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FunGene: 08-OCT-2024

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_001332
  • pan locus tag?: SAUPAN003727000
  • symbol: mscL
  • pan gene symbol?: mscL
  • synonym:
  • product: large conductance mechanosensitive channel protein MscL

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_001332
  • symbol: mscL
  • product: large conductance mechanosensitive channel protein MscL
  • replicon: chromosome
  • strand: -
  • coordinates: 1339863..1340225
  • length: 363
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    ATGTTAAAAGAATTCAAAGAGTTCGCCTTAAAAGGTAACGTCTTAGATTTAGCAATTGCT
    GTTGTGATGGGTGCAGCTTTCAACAAGATTATATCTTCATTAGTAGAAAATATCATTATG
    CCATTAATTGGTAAAATTTTCGGATCAGTTGATTTTGCTAAAGAATGGTCATTCTGGGGT
    ATTAAATACGGTTTATTTATCCAATCTGTTATCGACTTTATTATCATCGCGTTTGCTTTA
    TTCATCTTTGTTAAGATTGCAAATACATTAATGAAGAAAGAAGAAGCCGCAGAAGAAGCA
    GTTGTGGAAGAAAATGTTGTGTTATTAACTGAAATCAGAGATTTATTACGTGAGAAAAAA
    TAA
    60
    120
    180
    240
    300
    360
    363

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: JSNZ_001332
  • symbol: MscL
  • description: large conductance mechanosensitive channel protein MscL
  • length: 120
  • theoretical pI: 4.91293
  • theoretical MW: 13558.1
  • GRAVY: 0.685833

⊟Function[edit | edit source]

  • TIGRFAM:
    Cellular processes Cellular processes Adaptations to atypical conditions large conductance mechanosensitive channel protein (TIGR00220; HMM-score: 124.3)
  • TheSEED: data available for COL, N315, Newman, USA300_FPR3757
  • PFAM:
    no clan defined MscL; Large-conductance mechanosensitive channel, MscL (PF01741; HMM-score: 135.1)
    and 1 more
    Mim2; Mitochondrial import 2 (PF19117; HMM-score: 13.7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 2
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.0003
    • Cytoplasmic Membrane Score: 0.9526
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.047
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.019989
    • TAT(Tat/SPI): 0.002238
    • LIPO(Sec/SPII): 0.012643
  • predicted transmembrane helices (TMHMM): 2

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MLKEFKEFALKGNVLDLAIAVVMGAAFNKIISSLVENIIMPLIGKIFGSVDFAKEWSFWGIKYGLFIQSVIDFIIIAFALFIFVKIANTLMKKEEAAEEAVVEENVVLLTEIRDLLREKK

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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