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FunGene: 08-OCT-2024

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_001842
  • pan locus tag?: SAUPAN004774000
  • symbol: JSNZ_001842
  • pan gene symbol?: —
  • synonym:
  • product: exonuclease SbcCD subunit D

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_001842
  • symbol: JSNZ_001842
  • product: exonuclease SbcCD subunit D
  • replicon: chromosome
  • strand: -
  • coordinates: 1880945..1882141
  • length: 1197
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    ATGGTTAAATTTATTCATTGTTCGGATTTACATTTAGATAGTCCTTTCAAATCTAAGAGT
    CATATAAGCCCTAAAATTTTTGAGGATGTTCAAAAAAGTGCTTATGAAAGTTTTGAAAAT
    ATTGTAGATATTGCATTACAACAAGATGTTGATTTTGTAATTATCGCGGGTGATTTATTT
    GATAGTGAAAACAGAACATTACGTGCTGAAATTTTCTTAAAACAGCAATTTGAACGTTTA
    CAAAATGAACAAATCTTTGTTTATGTTTGTCATGGTAATCACGATCCTTTATCATCAAAG
    ATTTCATCAAACTGGCCAGATAATGTTTCTGTATTTTCAAATAAAGTTGAGACGTATGAA
    GCAATTACTAAATCTGGTGAAACAATTTATATTCACGGATTTAGTTATGAAAATAGAGCA
    AGTTATGAGAACAAGATTGATGAATATCCATCAAGTCAAGGCCAAAAAGGCATACATATT
    GGTGTCTTGCATGGTACGTATAGTAAATCTTCAGTTAACGAAAGATATACCGAGTTCATT
    TTAGAAGATTTAAACAGTAAATTGTATCATTATTGGGCTTTAGGTCATATACATGAACGT
    CAACAATTAAGTGATATGCCTGTAATTAACTATTCAGGTATTATTCAAGGTAGACATTTT
    AATGAGCAAGGTGAAAAAGGTTGCTTATTAATCGAGGGTGACCACTTAAAATTAAAGACT
    AAATTTTATCCTACACAGTATATTAGATTTGAAGAAGCAACTATTGAAACGGATAAGACA
    TCTAAGCAAGGTTTATACGAGGTCATTCAAAACTTTAAAGAACAAGTGAGAGAAGAAGGA
    AAAGCCTTTTATCGTTTAACGCTTGTTATTAATAGTGAGACATTAATTTCACCTCAAGAT
    TTATTACAAGTTGAAGAAATGATTACAGATTATGAAGAAAACGAAAATCAATTTGTATAT
    ATTGATGAGTTAAAAATACAATATGCACAAAATGATGAGTCACCTTTAGTTAATGAATTT
    TCAGCGGAATTATTAGTCGATCAAGCTGTTTTTGATAAAGCGATGTCAGATTTATATTTA
    AATCCAAGGGCATCAAAGTTCCTAGACGATTATGGAACATTCGACCATACAGCATTAGTT
    AATCGTGCTGAAGAAATATTAAAAGCTGAAATGAGAGGTGAACAAAATGATAATTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1197

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: JSNZ_001842
  • symbol: JSNZ_001842
  • description: exonuclease SbcCD subunit D
  • length: 398
  • theoretical pI: 4.56594
  • theoretical MW: 46194.1
  • GRAVY: -0.558794

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing DNA metabolism DNA replication, recombination, and repair exonuclease SbcCD, D subunit (TIGR00619; HMM-score: 59)
    and 5 more
    metallophosphoesterase, DNA ligase-associated (TIGR04123; HMM-score: 21)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair DNA repair protein (mre11) (TIGR00583; HMM-score: 20.8)
    putative phosphoesterase (TIGR03729; HMM-score: 20.1)
    Unknown function Enzymes of unknown specificity phosphodiesterase, MJ0936 family (TIGR00040; EC 3.1.-.-; HMM-score: 15.4)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Thiamine hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase (TIGR00097; EC 2.7.1.49,2.7.4.7; HMM-score: 10.9)
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    Calcineurin (CL0163) Metallophos; Calcineurin-like phosphoesterase (PF00149; HMM-score: 58.2)
    and 2 more
    Metallophos_2; Calcineurin-like phosphoesterase superfamily domain (PF12850; HMM-score: 30.5)
    P-loop_NTPase (CL0023) DUF835; Protein of unknown function (DUF835) (PF05763; HMM-score: 18.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9846
    • Cytoplasmic Membrane Score: 0.0137
    • Cell wall & surface Score: 0.001
    • Extracellular Score: 0.0006
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.001765
    • TAT(Tat/SPI): 0.00019
    • LIPO(Sec/SPII): 0.000873
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MVKFIHCSDLHLDSPFKSKSHISPKIFEDVQKSAYESFENIVDIALQQDVDFVIIAGDLFDSENRTLRAEIFLKQQFERLQNEQIFVYVCHGNHDPLSSKISSNWPDNVSVFSNKVETYEAITKSGETIYIHGFSYENRASYENKIDEYPSSQGQKGIHIGVLHGTYSKSSVNERYTEFILEDLNSKLYHYWALGHIHERQQLSDMPVINYSGIIQGRHFNEQGEKGCLLIEGDHLKLKTKFYPTQYIRFEEATIETDKTSKQGLYEVIQNFKEQVREEGKAFYRLTLVINSETLISPQDLLQVEEMITDYEENENQFVYIDELKIQYAQNDESPLVNEFSAELLVDQAVFDKAMSDLYLNPRASKFLDDYGTFDHTALVNRAEEILKAEMRGEQNDN

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Blanca Taboada, Karel Estrada, Ricardo Ciria, Enrique Merino
    Operon-mapper: a web server for precise operon identification in bacterial and archaeal genomes.
    Bioinformatics: 2018, 34(23);4118-4120
    [PubMed:29931111] [WorldCat.org] [DOI] (I p)

⊟Relevant publications[edit | edit source]

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