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NCBI: 06-JUL-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_1232 [new locus tag: NWMN_RS06960 ]
  • pan locus tag?: SAUPAN003688000
  • symbol: NWMN_1232
  • pan gene symbol?: —
  • synonym:
  • product: ABC transporter permease

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_1232 [new locus tag: NWMN_RS06960 ]
  • symbol: NWMN_1232
  • product: ABC transporter permease
  • replicon: chromosome
  • strand: +
  • coordinates: 1356447..1357178
  • length: 732
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    ATGATACTAAGTTACTTGAAAATCGAATTTAAAGTTATAATGCGTAAAAAAACAACATTA
    ATATTATCTATTTTATTTCCTGTTATATTCTATATATTATTTACTTCGATATTGGAATTG
    CCGGAAGATGTTAAACCTAAATTTTATAAAGAGTATATGTATAGTATGACGGTTTATAGT
    TTGTTAAGTTTTAGTTTACTAACTTTTCCATTAGATATTATTAATGAAAAACAAAATGAA
    TGGCGCCAAAGATTAATGGTAACACCATTTACTTTTACTAGTTATTATATTTCAAAAGTA
    GTGAAAACTATGCTGCAATTTGCAATAGCGATATTAGTTATTTTTATGGTTGGACATTTT
    TATAAAGGTGTTGCAATGAGTGCAGTTCAATGGTTAGAGTCAGGAATATTTTTATGGTTA
    GGTGCGTCTCTATTAATAACTTTTGGCATATTATTTTCTTTGTTAAATGATATTCAAAAA
    ACAAGTGCTTTAGCTAATATCGTAACAATTGGTTTAGCAGTATTAGGTGGATTGTGGTTT
    CCGATAAACACATTTCCAAATTGGCTTCAACATGTTGCTCATGTTTTACCGAGCTATCAT
    TTGCGTAAACTAGGTGTAGATATTGCTTCAAATCATCATATCAATTTAATATCATTTGCT
    ATAATACTCTTGTATGCTTTAGGGAGTATAATAGCAGTATATTGTATTAGTCATTTTAAA
    AGGGCGGAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    732

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: NWMN_1232 [new locus tag: NWMN_RS06960 ]
  • symbol: NWMN_1232
  • description: ABC transporter permease
  • length: 243
  • theoretical pI: 9.7801
  • theoretical MW: 27918.3
  • GRAVY: 0.753498

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Other daunorubicin resistance ABC transporter membrane protein (TIGR01247; HMM-score: 26.3)
    ABC transporter efflux protein, DrrB family (TIGR00025; HMM-score: 25.3)
    and 3 more
    Unclassified Role category not yet assigned daunorubicin resistance protein C (TIGR01248; HMM-score: 17.8)
    Metabolism Transport and binding proteins Other pigment precursor permease (TIGR00955; HMM-score: 6.3)
    Metabolism Transport and binding proteins Other pleiotropic drug resistance family protein (TIGR00956; HMM-score: 2.1)
  • TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
  • PFAM:
    ABC-2 (CL0181) ABC2_membrane_3; ABC-2 family transporter protein (PF12698; HMM-score: 62.7)
    ABC2_membrane; ABC-2 type transporter (PF01061; HMM-score: 50.6)
    and 4 more
    ABC2_membrane_4; ABC-2 family transporter protein (PF12730; HMM-score: 20.1)
    ABC2_membrane_2; ABC-2 family transporter protein (PF12679; HMM-score: 19.2)
    no clan defined TctB; Tripartite tricarboxylate transporter TctB family (PF07331; HMM-score: 14)
    IncD; Inclusion membrane protein D (PF17628; HMM-score: 7.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 6
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: 0.17
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.006567
    • TAT(Tat/SPI): 0.000157
    • LIPO(Sec/SPII): 0.003229
  • predicted transmembrane helices (TMHMM): 6

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MILSYLKIEFKVIMRKKTTLILSILFPVIFYILFTSILELPEDVKPKFYKEYMYSMTVYSLLSFSLLTFPLDIINEKQNEWRQRLMVTPFTFTSYYISKVVKTMLQFAIAILVIFMVGHFYKGVAMSAVQWLESGIFLWLGASLLITFGILFSLLNDIQKTSALANIVTIGLAVLGGLWFPINTFPNWLQHVAHVLPSYHLRKLGVDIASNHHINLISFAIILLYALGSIIAVYCISHFKRAE

⊟Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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