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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_RS04960 [old locus tag: NWMN_0886 ]
  • pan locus tag?: SAUPAN003193000
  • symbol: NWMN_RS04960
  • pan gene symbol?: ltaA
  • synonym:
  • product: MFS transporter

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_RS04960 [old locus tag: NWMN_0886 ]
  • symbol: NWMN_RS04960
  • product: MFS transporter
  • replicon: chromosome
  • strand: -
  • coordinates: 982491..983699
  • length: 1209
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_009641 (982491..983699) NCBI
  • BioCyc:
  • MicrobesOnline: see NWMN_0886

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    ATGGAAAGGTTCCTTTATATGCAAGATTCTTCGTTAAATAATTACGCTAATCATAAAAAT
    TTCATTTTAATGCTTATTATCTTATTTTTAATGGAATTTGCGAGAGGCATGTATATCCTA
    AGCTATATTAATTTCTTGCCAACAGTTACATCCATTGCTGTAGCAATAACGTCTCTAGCA
    TTTTCAATACATTTTATTGCTGATGCATCTACAAACTTTGTTATAGGATTTTTACTGAAA
    AAATTCGGCACAAAAATCGTTTTAACGACTGGATTTATTTTAGCATTTACAAGTTTATTT
    TTAGTTATTTGGTTTCCAGCATCACCTTTTGTAATCATATTTAGTGCTATGATGCTCGGT
    ATTGCAGTTAGTCCTATTTGGGTCATTATGTTATCCAGTGTTGAAGAAGATAAACGTGGC
    AAACAAATGGGCTATGTTTATTTTTCATGGTTGTTAGGCCTATTGGTAGGTATGGTTTTT
    ATGAATCTACTTATCAAAGTGCACCCAACACGCTTTGCCTTCATGATGTCTTTAGTCGTT
    TTAATTGCATGGATATTATATTATTTTGTCGATGTAAAGTTAACAAATTATAATACTCGT
    CCAGTTAAAGCTCAATTGAGACAAATTGTTGATGTGACAAAGCGCCATTTATTGTTGTTC
    CCTGGTATTCTTTTACAAGGTGCCGCAATTGCTGCCCTAGTTCCTATATTACCAACATAT
    GCTACTAAGGTTATTAACGTAAGCACAATTGAATATACTGTTGCAATCATTATTGGTGGT
    ATCGGCTGTGCAGTTTCGATGCTATTTTTATCGAAACTAATAGATAACCGCAGCAGAAAC
    TTTATGTATGGTGTTATTCTAAGCGGATTTATTTTATACATGATATTAATTTTTACTCTA
    TCTATGATTGTTAATATTCACATCTTGTGGATTATCGCTTTAGCTATCGGTCTAATGTAT
    GGCATCTTATTACCAGCATGGAATACCTTTATGGCACGATTTATCAAATCAGATGAACAA
    GAAGAAACTTGGGGTGTTTTTAATAGTATCCAAGGATTCGGCTCAATGATAGGGCCATTA
    TTTGGCGGATTAATTACACAATTTACCAACAATTTAAACAATACATTTTATTTCTCGGCA
    TTAATCTTTTTAGTCTTAGCTGTATTTTATGGAAGCTACTTTATAGTAAATAGAGAAAAA
    GCTAAGTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1209

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: NWMN_RS04960 [old locus tag: NWMN_0886 ]
  • symbol: NWMN_RS04960
  • description: MFS transporter
  • length: 402
  • theoretical pI: 9.88498
  • theoretical MW: 45457.4
  • GRAVY: 0.936318

⊟Function[edit | edit source]

  • TIGRFAM:
    multidrug resistance protein (TIGR00880; HMM-score: 49.9)
    and 5 more
    Metabolism Transport and binding proteins Cations and iron carrying compounds H+ Antiporter protein (TIGR00900; HMM-score: 27.9)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids D-galactonate transporter (TIGR00893; HMM-score: 19.5)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids phosphoglycerate transporter family protein (TIGR00881; HMM-score: 10)
    drug resistance transporter, Bcr/CflA subfamily (TIGR00710; HMM-score: 6.7)
    Metabolism Transport and binding proteins Other glycerol-3-phosphate transporter (TIGR00712; HMM-score: 5.2)
  • TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
  • PFAM:
    MFS (CL0015) MFS_1; Major Facilitator Superfamily (PF07690; HMM-score: 132)
    and 2 more
    MFS_1_like; MFS_1 like family (PF12832; HMM-score: 15.5)
    ATG22; Vacuole effluxer Atg22 like (PF11700; HMM-score: 7.9)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 12
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.007922
    • TAT(Tat/SPI): 0.000126
    • LIPO(Sec/SPII): 0.001861
  • predicted transmembrane helices (TMHMM): 12

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MERFLYMQDSSLNNYANHKNFILMLIILFLMEFARGMYILSYINFLPTVTSIAVAITSLAFSIHFIADASTNFVIGFLLKKFGTKIVLTTGFILAFTSLFLVIWFPASPFVIIFSAMMLGIAVSPIWVIMLSSVEEDKRGKQMGYVYFSWLLGLLVGMVFMNLLIKVHPTRFAFMMSLVVLIAWILYYFVDVKLTNYNTRPVKAQLRQIVDVTKRHLLLFPGILLQGAAIAALVPILPTYATKVINVSTIEYTVAIIIGGIGCAVSMLFLSKLIDNRSRNFMYGVILSGFILYMILIFTLSMIVNIHILWIIALAIGLMYGILLPAWNTFMARFIKSDEQEETWGVFNSIQGFGSMIGPLFGGLITQFTNNLNNTFYFSALIFLVLAVFYGSYFIVNREKAK

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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