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NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_RS06710 [old locus tag: NWMN_1191 ]
  • pan locus tag?: SAUPAN003584000
  • symbol: NWMN_RS06710
  • pan gene symbol?:
  • synonym:
  • product: transcriptional regulator

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_RS06710 [old locus tag: NWMN_1191 ]
  • symbol: NWMN_RS06710
  • product: transcriptional regulator
  • replicon: chromosome
  • strand: +
  • coordinates: 1313632..1314024
  • length: 393
  • essential: unknown other strains

Accession numbers[edit | edit source]

  • Location: NC_009641 (1313632..1314024) NCBI
  • BioCyc:
  • MicrobesOnline: see NWMN_1191

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    TTGAAAACGGTCGGTGAAGCGCTAAAAGGTAGACGTGAAAGGTTAGGAATGACTTTAACA
    GAATTAGAGCAACGTACTGGAATTAAACGTGAAATGCTAGTGCATATTGAAAATAATGAA
    TTCGATCAACTACCGAATAAAAATTACAGCGAAGGATTTATTAGAAAATATGCAAGCGTA
    GTAAATATTGAACCTAACCAATTAATTCAAGCTCATCAAGATGAAATTCCATCGAACCAA
    GCCGAATGGGACGAAGTAATTACAGTTTTCAATAATAATAAAGACTTAGATTATAAGAGT
    AAATCAAAAGAGCCAATACAATTATTAGTAATCATGGGTATTACAGTTTTAATAACTTTA
    TTGTTATGGATCATGTTAGTTTTAATATTTTAA
    60
    120
    180
    240
    300
    360
    393

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: NWMN_RS06710 [old locus tag: NWMN_1191 ]
  • symbol: NWMN_RS06710
  • description: transcriptional regulator
  • length: 130
  • theoretical pI: 5.24544
  • theoretical MW: 15113.4
  • GRAVY: -0.226154

Function[edit | edit source]

  • TIGRFAM:
    Unknown function General mobile mystery protein A (TIGR02612; HMM-score: 16.1)
  • TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
  • PFAM:
    HTH (CL0123) HTH_25; Helix-turn-helix domain (PF13413; HMM-score: 60.3)
    and 7 more
    HTH_19; Helix-turn-helix domain (PF12844; HMM-score: 37.1)
    HTH_3; Helix-turn-helix (PF01381; HMM-score: 25.1)
    HTH_31; Helix-turn-helix domain (PF13560; HMM-score: 24.1)
    Rubredoxin (CL0045) COX5B; Cytochrome c oxidase subunit Vb (PF01215; HMM-score: 14.9)
    no clan defined Tmemb_9; TMEM9 (PF05434; HMM-score: 13.6)
    HTH (CL0123) HTH_26; Cro/C1-type HTH DNA-binding domain (PF13443; HMM-score: 13.6)
    Sulfolobus_pRN; Sulfolobus plasmid regulatory protein (PF05584; HMM-score: 13.5)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helix: 1
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.00614
    • TAT(Tat/SPI): 0.000912
    • LIPO(Sec/SPII): 0.002503
  • predicted transmembrane helices (TMHMM): 1

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MKTVGEALKGRRERLGMTLTELEQRTGIKREMLVHIENNEFDQLPNKNYSEGFIRKYASVVNIEPNQLIQAHQDEIPSNQAEWDEVITVFNNNKDLDYKSKSKEPIQLLVIMGITVLITLLLWIMLVLIF

Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]