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NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_RS12095 [old locus tag: NWMN_2089 ]
  • pan locus tag?: SAUPAN005581000
  • symbol: NWMN_RS12095
  • pan gene symbol?: opuD2
  • synonym:
  • product: glycine/betaine ABC transporter permease

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_RS12095 [old locus tag: NWMN_2089 ]
  • symbol: NWMN_RS12095
  • product: glycine/betaine ABC transporter permease
  • replicon: chromosome
  • strand: -
  • coordinates: 2325363..2326925
  • length: 1563
  • essential: unknown other strains

Accession numbers[edit | edit source]

  • Location: NC_009641 (2325363..2326925) NCBI
  • BioCyc:
  • MicrobesOnline: see NWMN_2089

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    ATGAAAAATAAATCAGTAAGTCTAGTGTTTTGGGTATCTTTAGTGATATGTACGATATTT
    GTTGCTTTTGGAGCAATATTTCCGAAACAGTTAGAAAAACTCACGCAAAACATTACTACA
    TTTATTGCGCTACATTTTTCTTGGTATTATTTATTGCTCGTTTTAGTTATTTTATTTGTC
    TGTGTGTATATTTTATTTTCGAGATACGCAAACATTACATTAGGTGAAGAAGGCGAAGAT
    CCTGAATTCTCATTGCCGTCTTGGTTTGCTATGTTATTTAGTGCTGGTATGGGAATAGGA
    CTTGTGTTCTGGACAACGGCAGAACCAATCAGTCATGCCTTCAAATTAACGCCTATTCAT
    AAAGCTGGCACGCAATCTGCAATTAATGATGCAATGCAGTTTTCATTTTTCCATTGGGGG
    ATTCATGCATGGGCAGTCTATGGTATTGTCGCGCTAGTGTTTGCATATTTTAGCTTTCAT
    AAAGGATATCCTGGCTTAGTCAGCGCTACATTGACGCCTTTATTAGGTGAAAAGGCAATG
    CGTGGACCTTTAGGTGGTGCCATTGATGTATTGGCAGTCATAGCTACAGTAACAGGCGTT
    GCTGCAACATTAGGTTTCGGTGCATTGCAAATAAACGAAGGTTTACATTTTTTATTTAAT
    GTACCGAGTAACTTCACGATGCAAGTAATCTTGATTGTCATTGCAACCATATTATTTACT
    TGGTCAGCATGGTCAGGTATCGATAAAGGTATCAAAACGTTGAGTAATATCAACATGTTA
    CTTGCTTTTGTAGTACTTATTGGTCTTTTTATTGTTGGGCCAACGCTATACATTTTAAAT
    ACATTTACGAATGGTCTAGGTAATTATATTGCAAATTTCTTTAGTATGAGTTTACGCATT
    CCGACAGGTGGTCAAAAATTCCAATGGTTACAAAATTGGACAATCTTTTACTGGGCATGG
    TGGATATCTTGGGCACCATTTGTAGGTATATTTATTGCACGTGTGTCAAAAGGACGTACG
    ATTAAAGAATTTATTCTAGGTGTACTTTTTGTCCCGGCGTTAGTTTGCTTTATATTCTTT
    GCGGTATTCGGCGCGTCAGCAATTTACTTACAAGATAATCATATTGCCGATATTGCTAAA
    GCTGCGACAGAAACAGCAACTTTTGCGACGCTACAACATTATCCGCTAGGTTTTGTATTA
    AGCTTAATTACTTTACTTGTTATTATGATTTTCTTTGTTACATCAGCGGATTCGGCAACT
    TATGTTTTAGGTATGTTGAGTTCAAGTGGTGATATTAATCCGAAGTCATTTGTCAAAGTG
    AGTTGGGGTATCATTATGGCATTATTTGCAATCATCATGATTTACACAGGTGGTACTCAA
    GCAATTCAAAATTTATTAATCATTGCTGCGTTACCATTTTCCGTGGTCATTATAGCGATG
    ATATGGTCGCTTATAAAATCTTTGAGTGAGGAGAAACCGAGAAATAGTAATAAGGTTTTA
    ATTAAACATCGTGACCCAGATATTTTAGAATATCGTTCTTCAAAACATATTGACGAAAAT
    TAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1563

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: NWMN_RS12095 [old locus tag: NWMN_2089 ]
  • symbol: NWMN_RS12095
  • description: glycine/betaine ABC transporter permease
  • length: 520
  • theoretical pI: 8.91716
  • theoretical MW: 57635.7
  • GRAVY: 0.788654

Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Other transporter, betaine/carnitine/choline transporter (BCCT) family (TIGR00842; HMM-score: 528.4)
  • TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
  • PFAM:
    APC (CL0062) BCCT; BCCT, betaine/carnitine/choline family transporter (PF02028; HMM-score: 625.6)
    and 1 more
    M6PR (CL0226) ATG27; Autophagy-related protein 27 (PF09451; HMM-score: 12.5)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 12
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.017815
    • TAT(Tat/SPI): 0.000231
    • LIPO(Sec/SPII): 0.309842
  • predicted transmembrane helices (TMHMM): 12

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MKNKSVSLVFWVSLVICTIFVAFGAIFPKQLEKLTQNITTFIALHFSWYYLLLVLVILFVCVYILFSRYANITLGEEGEDPEFSLPSWFAMLFSAGMGIGLVFWTTAEPISHAFKLTPIHKAGTQSAINDAMQFSFFHWGIHAWAVYGIVALVFAYFSFHKGYPGLVSATLTPLLGEKAMRGPLGGAIDVLAVIATVTGVAATLGFGALQINEGLHFLFNVPSNFTMQVILIVIATILFTWSAWSGIDKGIKTLSNINMLLAFVVLIGLFIVGPTLYILNTFTNGLGNYIANFFSMSLRIPTGGQKFQWLQNWTIFYWAWWISWAPFVGIFIARVSKGRTIKEFILGVLFVPALVCFIFFAVFGASAIYLQDNHIADIAKAATETATFATLQHYPLGFVLSLITLLVIMIFFVTSADSATYVLGMLSSSGDINPKSFVKVSWGIIMALFAIIMIYTGGTQAIQNLLIIAALPFSVVIIAMIWSLIKSLSEEKPRNSNKVLIKHRDPDILEYRSSKHIDEN

Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]