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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

organism: Staphylococcus aureus Newman
locus tag: NWMN_RS14310 [old locus tag: NWMN_2493 ]
pan locus tag^?: SAUPAN006278000
symbol: NWMN_RS14310
pan gene symbol^?: —
synonym:
product: acyl esterase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

type: CDS
locus tag: NWMN_RS14310 [old locus tag: NWMN_2493 ]
symbol: NWMN_RS14310
product: acyl esterase
replicon: chromosome
strand: +
coordinates: 2737971..2739653
length: 1683
essential: unknown other strains

⊟Accession numbers[edit | edit source]

Location: NC_009641 (2737971..2739653) NCBI
BioCyc:
MicrobesOnline: see NWMN_2493

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

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ATGAACCAACATTTACTAGGAAATCCAAAATTAACTGTAACTCATGTCAATGAAGTTAAA
GCCGGTATTAACCACATCGTTGTCGACAGTGTTCAATATGGAAATCAAGAAATGATTATG
GAAAAAGATGGCACTGTGGAAATGCGCGATGGCGAAAAATTATATATTAATATTTTCAGA
CCAAATAAAGATGGCAAATTCCCTGTAGTTATGTCTGCAGATACTTACGGTAAAGATAAT
AAGCCTAAAATCACAAATATGGGTGCCCTTTGGCCAACATTAGGTACCATTCCGACATCT
AGTTTTACACCTGAAGAATCACCAGACCCAGGATTTTGGGTGCCAAATGATTATGTTGTA
GTTAAAGTTGCATTACGCGGTAGTGACAAATCCAAAGGCGTCTTATCTCCATGGTCAAAA
AGAGAAGCGGAAGATTATTACGAAGTGATTGAATGGGCAGCAAATCAGTCATGGAGTAAT
GGAAATATCGGGACAAATGGTGTTTCTTATCTTGCGGTGACTCAATGGTGGGTCGCATCA
TTAAATCCACCACATTTAAAAGCAATGATTCCTTGGGAAGGCTTAAATGATATGTATAGA
GAAGTAGCCTTTCACGGAGGTATACCAGATACTGGCTTTTATCGTTTCTGGACTCAAGGT
ATTTTTGCGAGATGGACAGATAATCCAAATATCGAAGATTTGATTCAAGCACAACAAGAA
CATCCTCTGTTCGATGATTTTTGGAAACAGCGTCAAGTGCCATTATCACAAATTAAAACA
CCTCTACTAACATGTGCTAGTTGGTCTACACAAGGTTTGCACAACCGTGGCTCTTTTGAA
GGATTTAAACAAGCTGCATCTGAAGAAAAATGGCTATATGTGCATGGACGTAAAGAGTGG
GAAAGTTACTACGCTAGAGAAAATCTCGAACGCCAAAAATCATTCTTTGATTTTTACCTT
AAAGAAGAAAATAACGATTGGAAAGATACGCCTCATGTCATTTATGAAGTTAGAGATCAA
TTTTATAAAGGCGAATTCAAATCAGCGTCAGCGTTCCCTTTACCTAACGCAGAATATACA
CCATTGTATTTGAATGCTGAAAATCACACATTGAATCATGCAAAGATTAGTAGCGCGCAT
GTCGCACAATATGACTCTGAAGATAAACAACAAGATGTAAGTTTTAAATATACGTTTGAC
AAAGATACTGAGTTAGTTGGAAACATGAACTTAAAACTATGGGTAAGCACTAAAGACTCA
GATGATATGGATTTATTTGCAGGTATTAAAAAGTTAGATCGTCGTGGTAATGAAGTTAAC
TTCCCTGATTTTAATCATATTGAAAATGGTCAAGTAGCTACTGGTTGGTTACGCGTATCA
CATCGTGAATTAGATCAAGAAAAATCCTCAATCGCGCAACCTTGGCATAAACATGAAACA
GAATTAAAGTTGTCACAAGATGAGATTGTACCTGTTGAAATCGAATTGTTACCTTCAGGC
ACGCTATTTAAACAAGGCGAAACATTGGAAGTTGTTGTAAAGGGTAGTGAAATTGTAATT
GGTAATAGTACTCCTGGCATGAAAACACGTTATGAACATGAAGAAACCGTAAATAAAGGC
ATGCACATGATTTATACTGGTGGTAAATATGATTCACAATTAATCATTCCTATCGTTAAT
TGA
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1683

⊟Protein[edit | edit source]

3IB3
PDB
3III
PDB

Protein Data Bank: 3IB3

Protein Data Bank: 3III

⊟General[edit | edit source]

locus tag: NWMN_RS14310 [old locus tag: NWMN_2493 ]
symbol: NWMN_RS14310
description: acyl esterase
length: 560
theoretical pI: 5.29295
theoretical MW: 64247.5
GRAVY: -0.6375

⊟Function[edit | edit source]

TIGRFAM:
Unknown function Enzymes of unknown specificity hydrolase CocE/NonD family protein (TIGR00976; HMM-score: 255.6)
TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
PFAM:
GBD (CL0202) PepX_C; X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain (PF08530; HMM-score: 162)
AB_hydrolase (CL0028) Peptidase_S15; X-Pro dipeptidyl-peptidase (S15 family) (PF02129; HMM-score: 142.8)

⊟Structure, modifications & cofactors[edit | edit source]

domains:
modifications:
cofactors:
effectors:

⊟Localization[edit | edit source]

PSORTb: unknown (no significant prediction)
- Cytoplasmic Score: 2.5
- Cytoplasmic Membrane Score: 2.5
- Cellwall Score: 2.5
- Extracellular Score: 2.5
- Internal Helices: 0
LocateP:
SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.008891
- TAT(Tat/SPI): 0.00032
- LIPO(Sec/SPII): 0.000827
predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

GI: 446994311 NCBI
RefSeq: WP_001071567 NCBI
UniProt: see NWMN_2493

⊟Protein sequence[edit | edit source]

MNQHLLGNPKLTVTHVNEVKAGINHIVVDSVQYGNQEMIMEKDGTVEMRDGEKLYINIFRPNKDGKFPVVMSADTYGKDNKPKITNMGALWPTLGTIPTSSFTPEESPDPGFWVPNDYVVVKVALRGSDKSKGVLSPWSKREAEDYYEVIEWAANQSWSNGNIGTNGVSYLAVTQWWVASLNPPHLKAMIPWEGLNDMYREVAFHGGIPDTGFYRFWTQGIFARWTDNPNIEDLIQAQQEHPLFDDFWKQRQVPLSQIKTPLLTCASWSTQGLHNRGSFEGFKQAASEEKWLYVHGRKEWESYYARENLERQKSFFDFYLKEENNDWKDTPHVIYEVRDQFYKGEFKSASAFPLPNAEYTPLYLNAENHTLNHAKISSAHVAQYDSEDKQQDVSFKYTFDKDTELVGNMNLKLWVSTKDSDDMDLFAGIKKLDRRGNEVNFPDFNHIENGQVATGWLRVSHRELDQEKSSIAQPWHKHETELKLSQDEIVPVEIELLPSGTLFKQGETLEVVVKGSEIVIGNSTPGMKTRYEHEETVNKGMHMIYTGGKYDSQLIIPIVN

⊟Experimental data[edit | edit source]

experimentally validated: data available for NCTC8325
protein localization: data available for COL
quantitative data / protein copy number per cell:
interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

regulator:

⊟Transcription pattern[edit | edit source]

S.aureus Expression Data Browser: data available for NCTC8325

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

Aureolib: no data available

⊟Protein stability[edit | edit source]

half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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