PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 26-AUG-2013

⊟Summary

• organism: Staphylococcus aureus N315
• locus tag: SA0058 [new locus tag: SA_RS00435 ]
• pan locus tag^?: SAUPAN000445000
• symbol: ccrA
• pan gene symbol^?: ccrA
• synonym:
• product: cassette chromosome recombinase A

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SA0058 [new locus tag: SA_RS00435 ]
• symbol: ccrA
• product: cassette chromosome recombinase A
• replicon: chromosome
• strand: -
• coordinates: 65047..66396
• length: 1350
• essential: no DEG

⊟Accession numbers

• Gene ID: 1122832 NCBI
• RefSeq: NP_373298 NCBI
• BioCyc: see SA_RS00435
• MicrobesOnline: 102324 MicrobesOnline

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
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  1021
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  1321
  
  ATGAAACAAGTCATAGGCTATTTACGTCAAAGTACGATGAAACAACAATCTCTTGCAGCA
  CAGAAACAGGCTATCGAAGCAATAGCCGAAAAACATCATATTCAACATATCAACTTTTAT
  AGCGACAAACAATCAGGACGCAAAGATAATCGTAGTGGGTATCGACAAATGACGCAATTA
  ATTCAACAAGGGCAATGTGACATATTATGTTGTTATCGTCTTAATAGATTACATCGTAAT
  CTGAAAAATGCATTAAAACTCATCAAATTATGTCAAACATACCATGTTCATATCTTAAGC
  GTACACGATGGTTACTTTGATATGGATCAAGCTTTCGACCGATTCAAGCTTAATATTTTT
  ATCAGCTTGGCCGAACTTGAATCAGATAACATTGGAGAACAAGTCAGAAATGGGCTTCAA
  GAAAAAGCAAAGCAAGGTCGATTGATTACAACCCATGCGCCCTTTGGTTACGAATATCAC
  AACGGAGCATTCATCATCAATCAAAATGAGTCACCAACGGTAAAGGCTGTATTCAATTAT
  TACATTAAAGGTCATGGTTATAAGAAAATTGCACAGTTATTAGAAGAAGATAACACGTAT
  ATCAATCGACAACCCTATCAAGTTCGTAACATTATCATCAATCCTAATTATTGTGGTCGT
  GTCAACAATCAATATGGCCAATTCGACAATATGTTTCCTTCTATTGTTTCCACAAGTATA
  TATGAGCAAGCGCAGAGACTTCGATCGCAAAAACAAATCAAACAGACATCTTCGGATAAC
  CAACTAAAACAAAAAATCAAATGCCCATGTTGTAATACAACACTTACGAATATGACCGTT
  AGAAAAAAGAATCATACATTACGTTACTACGTCTGTCCTAAAAACATGAATGCTTCTCGC
  TTTGTCTGTGATTTTAAAGGCATCAATGCACAAACACTTGAAGATAAAGTATTAGAAGTG
  TGCAAAGACTTTTATCAAAATCAACGCATCTACACAAAAATTAAAGGTGCGATTGACAAA
  CGCATCAAAAGACAAAGAAACATAGAAAAACATCACACATTGACTCAAGAACAACTGATA
  GAAAAGTTGGCACAAGGCATCATCGATGCAGAAACGTTCAGAGAACAAACGCAATCATTA
  CGTCAACAACCGCAACGCACTACATCTATCAATGGACATCAAATACAACACACCATTCAA
  AATATTATTCAAAAACGTTTCACGTTAAACATATTGTACCCCTATATTGAAACCATTCAC
  ATTACGAAAGATAAAAATCTTATAGGAATCTATTTCAAAAATGAACCACTCAATATCGTC
  AATCAAACCATGCAATCATCGATTGCATAA
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⊟Protein

⊟General

• locus tag: SA0058 [new locus tag: SA_RS00435 ]
• symbol: CcrA
• description: cassette chromosome recombinase A
• length: 449
• theoretical pI: 9.96026
• theoretical MW: 52606.9
• GRAVY: -0.686637

⊟Function

• TIGRFAM:
• TheSEED  :
  • Cassette chromosome recombinase A
• PFAM:
  no clan defined Resolvase; Resolvase, N terminal domain (PF00239; HMM-score: 127.6)
  and 5 more
  Recombinase; Recombinase (PF07508; HMM-score: 39.8)
  Zn_Beta_Ribbon (CL0167) Zn_ribbon_recom; Recombinase zinc beta ribbon domain (PF13408; HMM-score: 32.2)
  no clan defined Adenine_glyco; Methyladenine glycosylase (PF03352; HMM-score: 13.5)
  Zn_Beta_Ribbon (CL0167) zf-GRF; GRF zinc finger (PF06839; HMM-score: 12.2)
  no clan defined Lipin_mid; Lipin/Ned1/Smp2 multi-domain protein middle domain (PF16876; HMM-score: 11.5)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic
  • Cytoplasmic Score: 7.5
  • Cytoplasmic Membrane Score: 1.15
  • Cellwall Score: 0.62
  • Extracellular Score: 0.73
  • Internal Helices: 0
• LocateP: Intracellular
  • Prediction by SwissProt Classification: Cytoplasmic
  • Pathway Prediction: No pathway
  • Intracellular possibility: 1
  • Signal peptide possibility: -1
  • N-terminally Anchored Score: 1
  • Predicted Cleavage Site: No CleavageSite
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.017214
  • TAT(Tat/SPI): 0.002189
  • LIPO(Sec/SPII): 0.002199
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI: 15925765 NCBI
• RefSeq: NP_373298 NCBI
• UniProt: A0A0H3JK36 UniProt

⊟Protein sequence

• MKQVIGYLRQSTMKQQSLAAQKQAIEAIAEKHHIQHINFYSDKQSGRKDNRSGYRQMTQLIQQGQCDILCCYRLNRLHRNLKNALKLIKLCQTYHVHILSVHDGYFDMDQAFDRFKLNIFISLAELESDNIGEQVRNGLQEKAKQGRLITTHAPFGYEYHNGAFIINQNESPTVKAVFNYYIKGHGYKKIAQLLEEDNTYINRQPYQVRNIIINPNYCGRVNNQYGQFDNMFPSIVSTSIYEQAQRLRSQKQIKQTSSDNQLKQKIKCPCCNTTLTNMTVRKKNHTLRYYVCPKNMNASRFVCDFKGINAQTLEDKVLEVCKDFYQNQRIYTKIKGAIDKRIKRQRNIEKHHTLTQEQLIEKLAQGIIDAETFREQTQSLRQQPQRTTSINGHQIQHTIQNIIQKRFTLNILYPYIETIHITKDKNLIGIYFKNEPLNIVNQTMQSSIA

⊟Experimental data

• experimentally validated:
• protein localization:
• quantitative data / protein copy number per cell:
• interaction partners:

⊟Expression & Regulation

⊟Operon

• MicrobesOnline: ccrB < ccrA

⊟Regulation

• regulator:

⊟Transcription pattern

• S.aureus Expression Data Browser: no data available

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications