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PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 26-AUG-2013

Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA0405 [new locus tag: SA_RS02315 ]
  • pan locus tag?: SAUPAN002148000
  • symbol: lpl9
  • pan gene symbol?: lpl7
  • synonym:
  • product: hypothetical protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SA0405 [new locus tag: SA_RS02315 ]
  • symbol: lpl9
  • product: hypothetical protein
  • replicon: chromosome
  • strand: +
  • coordinates: 464686..465501
  • length: 816
  • essential: no DEG

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    ATGATGGAGTATATAAAAAAAATTGCTTTGTACATGAGTGTATTACTTTTAATCATTTTT
    ATTGGGGGATGTGGAAATATGAAAGAAGAACAGAAAAAAGAAGCAAATACAAATAAAACA
    GATTCAAAAGAAGAAAAAATCAAAAAGAGTTTTGCGAAAACGTTAGATATGTATCCAATT
    AAGAATCTCGAGGAACTATATGACAAAGAAGGCTATCGAGATGGCGAATTTGAAAAAGGT
    GACAAAGGGATGTGGACGATATATACAGATTTCGCCAAAAGTAATAAACCGGGTGAACTA
    AGTAATGAAGGCATGGTCTTGTACTTAGATAGAAACACACGCACAGCTAAGGGGTACTAC
    TTTGTCAGGACGTTTTATCGCAAGGATAAATTACCTGATAGAAAAAATTATAAAGTTGAA
    ATGAAAAATAATAAAATTATCTTATTAGACAAGGTAGAAGATCCAAATCTAAAAAAGAGA
    ATAGAAAACTTTAAATTTTTCGGACAATATGCAAATCTTAAAGAATTGAAAAACTACAGC
    AATGGTGATGTCTCAATTAATGAGAATGTTCCAAGTTATGACGTGAAATATAAAATGAGT
    AATAAAGATGAAAATGTTAAGCAATTAAGAAGTCGTTATAATATTCCTACTGATAAATCA
    CCGGTATTAAAAATGCATATTGATGGTAATTTGAAAGGAAGTTCCGTTGGAGATAGGAAG
    TTAGAAATTGATTTTTCGAAACGTGAAAATAGCCATTTATCAGTAATAGATTCTTTGGAT
    TACCAGCCAGCGAAGGTGGATGAAGATGAAAGATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    816

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SA0405 [new locus tag: SA_RS02315 ]
  • symbol: Lpl9
  • description: hypothetical protein
  • length: 271
  • theoretical pI: 9.48806
  • theoretical MW: 31774.1
  • GRAVY: -0.938376

Function[edit | edit source]

  • TIGRFAM:
    Staphylococcus tandem lipoproteins (TIGR01742; HMM-score: 398.4)
    and 3 more
    Cellular processes Cellular processes Sporulation and germination sporulation lipoprotein, YhcN/YlaJ family (TIGR02898; HMM-score: 13.5)
    Cellular processes Cellular processes Cell division putative protein insertion permease FtsX (TIGR00439; HMM-score: 9.4)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking putative protein insertion permease FtsX (TIGR00439; HMM-score: 9.4)
  • TheSEED  :
    • Tandem lipoprotein within Pathogenicity island
  • PFAM:
    LolA_LolB (CL0048) DUF576; Csa1 family (PF04507; HMM-score: 372.3)
    and 1 more
    ABC-2 (CL0181) ABC2_membrane_3; ABC-2 family transporter protein (PF12698; HMM-score: 9.2)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 3.33
    • Cellwall Score: 3.33
    • Extracellular Score: 3.33
    • Internal Helix: 1
  • LocateP: Lipid anchored
    • Prediction by SwissProt Classification: Extracellular
    • Pathway Prediction: Sec-(SPII)
    • Intracellular possibility: 0.17
    • Signal peptide possibility: 0
    • N-terminally Anchored Score: -1
    • Predicted Cleavage Site: IFIGGCG
  • SignalP: Signal peptide LIPO(Sec/SPII) length 23 aa
    • SP(Sec/SPI): 0.000517
    • TAT(Tat/SPI): 0.000066
    • LIPO(Sec/SPII): 0.999096
    • Cleavage Site: CS pos: 23-24. IGG-CG. Pr: 0.9996
  • predicted transmembrane helices (TMHMM): 1

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MMEYIKKIALYMSVLLLIIFIGGCGNMKEEQKKEANTNKTDSKEEKIKKSFAKTLDMYPIKNLEELYDKEGYRDGEFEKGDKGMWTIYTDFAKSNKPGELSNEGMVLYLDRNTRTAKGYYFVRTFYRKDKLPDRKNYKVEMKNNKIILLDKVEDPNLKKRIENFKFFGQYANLKELKNYSNGDVSINENVPSYDVKYKMSNKDENVKQLRSRYNIPTDKSPVLKMHIDGNLKGSSVGDRKLEIDFSKRENSHLSVIDSLDYQPAKVDEDER

Experimental data[edit | edit source]

  • experimentally validated: data available for COL
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]