From AureoWiki
Jump to navigation Jump to search

NCBI: 26-AUG-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA1011 [new locus tag: SA_RS05755 ]
  • pan locus tag?: SAUPAN003428000
  • symbol: SA1011
  • pan gene symbol?: ssl14
  • synonym:
  • product: superantigen-like protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SA1011 [new locus tag: SA_RS05755 ]
  • symbol: SA1011
  • product: superantigen-like protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1144655..1145380
  • length: 726
  • essential: no DEG other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    ATGAAAAAGAACATCATGAATAAATTAGTTTTATCAACAGCATTGTTACTTTTAGGAACC
    ACATCAACACAACTTCCTAAAACACCAATCAGTTTTTCATCTGAAGCAAAAGCCTATAAT
    ATCAGTGAAAACGAGACTAATATCAATGAGTTAATCAAATATTACACTCAGCCGCATTTT
    TCATTATCTGGAAAATGGCTATGGCAAAAGCCCAATGGTAGCATTCATGCAACATTGCAA
    ACGTGGGTTTGGTATAGTCATATTCAAGTGTTTGGATCCGAGAGTTGGGGAAACATTAAT
    CAGTTAAGAAATAAATACGTTGATATATTTGGAACTAAAGATGAGGACACAGTTGAAGGT
    TACTGGACTTATGATGAAACATTTACTGGTGGTGTTACGCCAGCAGCTACTTCATCTGAT
    AAACCTTATAGACTATTTTTAAAATATAGTGATAAACAACAAACTATCATCGGTGGACAT
    GAATTTTACAAAGGAAATAAACCAGTATTAACTTTAAAAGAATTAGATTTCCGTATTCGT
    CAAACATTAATAAAGAATAAAAAGTTATATAACGGAGAATTTAATAAAGGTCAAATTAAG
    ATAACTGCTGATGGAAATAATTACACGATTGATTTAAGTAAAAAGTTAAAATTAACTGAC
    ACAAACCGTTATGTTAAAAATCCTAAAAATGCACAAATTGAAGTCATACTCGAAAAATCT
    AACTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    726

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SA1011 [new locus tag: SA_RS05755 ]
  • symbol: SA1011
  • description: superantigen-like protein
  • length: 241
  • theoretical pI: 9.89912
  • theoretical MW: 27693.2
  • GRAVY: -0.625726

⊟Function[edit | edit source]

  • TIGRFAM:
  • TheSEED  :
    • Phage exotoxin
  • PFAM:
    Ant-toxin_C (CL0386) Stap_Strp_tox_C; Staphylococcal/Streptococcal toxin, beta-grasp domain (PF02876; HMM-score: 32.3)
    and 2 more
    no clan defined Dicty_CAD; Cell-cell adhesion domain (PF05720; HMM-score: 13.8)
    Lsr2; Lsr2 (PF11774; HMM-score: 13.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Extracellular
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0.01
    • Cellwall Score: 0.01
    • Extracellular Score: 9.98
    • Internal Helices: 0
  • LocateP: Secretory(released) (with CS)
    • Prediction by SwissProt Classification: Extracellular
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: -0.17
    • Signal peptide possibility: 1
    • N-terminally Anchored Score: -1
    • Predicted Cleavage Site: SFSSEAKA
  • SignalP: Signal peptide SP(Sec/SPI) length 38 aa
    • SP(Sec/SPI): 0.832667
    • TAT(Tat/SPI): 0.00689
    • LIPO(Sec/SPII): 0.148582
    • Cleavage Site: CS pos: 38-39. AKA-YN. Pr: 0.3880
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MKKNIMNKLVLSTALLLLGTTSTQLPKTPISFSSEAKAYNISENETNINELIKYYTQPHFSLSGKWLWQKPNGSIHATLQTWVWYSHIQVFGSESWGNINQLRNKYVDIFGTKDEDTVEGYWTYDETFTGGVTPAATSSDKPYRLFLKYSDKQQTIIGGHEFYKGNKPVLTLKELDFRIRQTLIKNKKLYNGEFNKGQIKITADGNNYTIDLSKKLKLTDTNRYVKNPKNAQIEVILEKSN

⊟Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Ilse Jongerius, Jörg Köhl, Manoj K Pandey, Maartje Ruyken, Kok P M van Kessel, Jos A G van Strijp, Suzan H M Rooijakkers
Staphylococcal complement evasion by various convertase-blocking molecules.
J Exp Med: 2007, 204(10);2461-71
[PubMed:17893203] [WorldCat.org] [DOI] (P p)

Retrieved from "http://aureowiki.med.uni-greifswald.de/index.php?title=SA1011&oldid=94154"