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NCBI: 26-AUG-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA2106 [new locus tag: SA_RS12105 ]
  • pan locus tag?: SAUPAN005792000
  • symbol: SA2106
  • pan gene symbol?: spdB
  • synonym:
  • product: hypothetical protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SA2106 [new locus tag: SA_RS12105 ]
  • symbol: SA2106
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 2368926..2369663
  • length: 738
  • essential: no DEG other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    GTGGAAAATGAAAAAAAGAAATACACGTTTAAAGATATAGCATGGAGAGATTTGCTTATA
    ATTCCAATTATAGGTGTTATATTTTATGCACTCACAATTGCAGCTTACATAGGACCAATT
    TTGTTTGGTTATTATGAAATCGATAGTAATCTGATATTTGTAGCGACTATCACACAAGCT
    TTAGCATATACGATTGGGATTGGCGCATTTTATTTATTTCATTTAAAAGTGATGCCATCA
    AGGCTTCGAGCTGGTTTTGCGTATATCAAAAAATATTGGCTTAGATTGTCAATAACGTAT
    ATTATTGCTCTCATCTTAATTTATACATATGAATATATGACACAGTTTCTACCTAAACAT
    TTGCAATATAGTGAAACAGCCAATGAACTTGAGCTAAATAAAATGTTTGAAGTGCCTGCA
    TTTTTACCTGTAGCATTCTTATTAATTGTGATTGTAGGTCCAATAGTTGAAGAAATCGTA
    TTTAGACATATTTTAATTGGAGAATTAGGTAAGAAGTTTAATTTTATAGCTATGAGTATT
    GTTTCGGTGTTCTTATTTGCATTTATTCATGTGACTGATGCAAAGTCGCCGTTTGAGTTT
    GGTCCATATCTCATACTATCCATCATATTAGTTTTCACTTATTTAAAATCTGGAAGAAAC
    CTAGGTTCAACAATTGCATTACATATAGCAAATAATTTTGTTTCTTTCGTTATATCAGTA
    ATAAGTATTTATGCGTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    738

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SA2106 [new locus tag: SA_RS12105 ]
  • symbol: SA2106
  • description: hypothetical protein
  • length: 245
  • theoretical pI: 9.19765
  • theoretical MW: 28034.3
  • GRAVY: 0.82

⊟Function[edit | edit source]

  • TIGRFAM:
  • TheSEED  :
    • Protein of pXO2-46
  • PFAM:
    Peptidase_U (CL0472) Abi; CAAX protease self-immunity (PF02517; HMM-score: 52.5)
    and 1 more
    no clan defined DUF2798; Protein of unknown function (DUF2798) (PF11391; HMM-score: 12.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 7
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: 0.17
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.009267
    • TAT(Tat/SPI): 0.000163
    • LIPO(Sec/SPII): 0.002173
  • predicted transmembrane helices (TMHMM): 7

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MENEKKKYTFKDIAWRDLLIIPIIGVIFYALTIAAYIGPILFGYYEIDSNLIFVATITQALAYTIGIGAFYLFHLKVMPSRLRAGFAYIKKYWLRLSITYIIALILIYTYEYMTQFLPKHLQYSETANELELNKMFEVPAFLPVAFLLIVIVGPIVEEIVFRHILIGELGKKFNFIAMSIVSVFLFAFIHVTDAKSPFEFGPYLILSIILVFTYLKSGRNLGSTIALHIANNFVSFVISVISIYA

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Matthew B Frankel, Brandon M Wojcik, Andrea C DeDent, Dominique M Missiakas, Olaf Schneewind
ABI domain-containing proteins contribute to surface protein display and cell division in Staphylococcus aureus.
Mol Microbiol: 2010, 78(1);238-52
[PubMed:20923422] [WorldCat.org] [DOI] (I p)

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