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NCBI: 26-AUG-2013
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus N315
- locus tag: SA2476 [new locus tag: SA_RS14170 ]
- pan locus tag?: SAUPAN006440000
- symbol: SA2476
- pan gene symbol?: —
- synonym:
- product: hypothetical protein
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SA2476 [new locus tag: SA_RS14170 ]
- symbol: SA2476
- product: hypothetical protein
- replicon: chromosome
- strand: -
- coordinates: 2787227..2788834
- length: 1608
- essential: no DEG other strains
⊟Accession numbers[edit | edit source]
- Gene ID: 1125406 NCBI
- RefSeq: NP_375803 NCBI
- BioCyc: see SA_RS14170
- MicrobesOnline: 104829 MicrobesOnline
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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1561GTGCTAGTAGTTGGTGCTTCAGGTAGTGGTAAATCGACTTTTGCAAATTGCATAAACGGA
TTAATTCCATTTAAAACTAAAGGTAACATAACCGGGGAACTATATATAAATAATCAAGAT
GCAACCGTTAGTTGTTTACATGATAGATCTAATGTTGTTGGTACAGTTTTACAAGATACA
GATGGACAGTTCATAGGCTTAACAGCAGCTGAAGATATGGCCTTTTTATTAGAAAATAAT
TGTGTTGAACAAGATGATATGAAGAAAAATGTAAGTTATTGGGCTGAAAAAGTTGGCATG
ATAGAACATTTAAATCACCGACCGCAAGATTTATCTGGAGGTCAAAAACAACGCGTTTCA
TTAGGTGGTATATTAATCCATCGTACGCCTATTTTAATATTGGATGAGCCGCTGGCCAAT
TTAGATCCTGCGACAGGACATGAAACGCTGAGATTGTTAAACAATATTCATGAAGAAACA
AAGTCAACGATGATTATTGTCGAACATCGATTAGAAGAATCATTAGATGATACGTTTGAT
AGAGTTCTTCTTTTTAAAGATGGAAAAATCATCGCTAATACAACGCCTAGTGATTTGCTA
AAATCATCTAAGCTTAAAGAAGCAGGCATACGTGAACCATTATACTGTACAGCGCTTAAA
TATGCAGAAGTAGATGTCGAATCCATTGATAACTTAGCGAATTTACGTGACGTTTGTATG
AGTGAACATGTTAAATTTAAAGTGAAAAAATGGATAGATGAAACATCTGCAAATAATGAT
AATAAGTACAAATCTGAACCGCTATTAGAATTAAATGAGGTATGTGTTCAATATAGTGAC
TATAGTAATAGTGTACTTAATAATGTTCAATTAAATGTTTATAGAAGAGAAATGCTTAGT
ATAGTTGGTCACAATGGTGCCGGCAAATCAACACTTGCTAAAGCAATTTGTGGATTTTTA
GATATAACAGGTAATATCCAATTTTGTAATAGGGGATTTAATCAATTGTCAATTAGCGAA
CGATCTGAATTCGTAGGTTATGTGATGCAAAATCCAAATCATATGATTTCTGAAAAAATG
ATTTACGATGAAGTAGCATTAGGGTTAAGAGCACGAGGTATGAAAGAATCAGATATAAAG
ATACGAGTAGAGAATGTGCTCAAAATATGCGGACTTTATGCATTTCGGAATTGGCCAATT
GCAGCTTTAAGCTATGGTCAAAAAAAGAGGGTCACTATAGCATCTGTTTTAGTCTTAAAT
CCGGAAATAATCATATTGGATGAACCGACTGCTGGTCAAGATTTCTATCATTATAATGAG
ATAATGTCATTTTTAATTGAGCTAAACAGACAGGGAAAGACGATTATTATGATTACGCAT
GATATGCATTTATTGTCTGAGTATAGTTCAAGAACAGTTGTATTATCAAAAGGACAAGTC
GTTGCTGATACCACGCCAGTATTGATATTAAATGATAAAAAAATCTGTGAGATTGCATCA
TTGAGACAAACATCGCTATTTGAAATGGCCGAATATATAGGGATTAGCGAGCCACAGAAA
TTAGTACAATTATTTATTAACCATGATAGGAAGGTGAGACGCCAATGA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SA2476 [new locus tag: SA_RS14170 ]
- symbol: SA2476
- description: hypothetical protein
- length: 535
- theoretical pI: 6.16625
- theoretical MW: 60147.6
- GRAVY: -0.193271
⊟Function[edit | edit source]
- reaction: EC 3.6.3.-? ExPASy
- TIGRFAM: Transport and binding proteins Unknown substrate energy-coupling factor transporter ATPase (TIGR04520; EC 3.6.3.-; HMM-score: 358.2)Transport and binding proteins Unknown substrate energy-coupling factor transporter ATPase (TIGR04521; EC 3.6.3.-; HMM-score: 321.2)and 82 moreTransport and binding proteins Cations and iron carrying compounds cobalt ABC transporter, ATP-binding protein (TIGR01166; HMM-score: 234.8)Cellular processes Cell division cell division ATP-binding protein FtsE (TIGR02673; HMM-score: 228.4)Transport and binding proteins Anions sulfate ABC transporter, ATP-binding protein (TIGR00968; EC 3.6.3.25; HMM-score: 204.3)Transport and binding proteins Amino acids, peptides and amines putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein (TIGR03265; HMM-score: 197.8)Transport and binding proteins Anions phosphate ABC transporter, ATP-binding protein (TIGR00972; EC 3.6.3.27; HMM-score: 194.4)Cellular processes Toxin production and resistance putative bacteriocin export ABC transporter, lactococcin 972 group (TIGR03608; HMM-score: 191.3)Transport and binding proteins Unknown substrate putative bacteriocin export ABC transporter, lactococcin 972 group (TIGR03608; HMM-score: 191.3)Cellular processes Pathogenesis type I secretion system ATPase (TIGR03375; HMM-score: 188.6)Protein fate Protein and peptide secretion and trafficking type I secretion system ATPase (TIGR03375; HMM-score: 188.6)Transport and binding proteins Other thiamine ABC transporter, ATP-binding protein (TIGR01277; EC 3.6.3.-; HMM-score: 185.6)Transport and binding proteins Anions phosphonate ABC transporter, ATP-binding protein (TIGR02315; EC 3.6.3.28; HMM-score: 185.2)2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT (TIGR03258; HMM-score: 184.3)Transport and binding proteins Amino acids, peptides and amines glycine betaine/L-proline transport ATP binding subunit (TIGR01186; HMM-score: 183.8)Transport and binding proteins Anions molybdate ABC transporter, ATP-binding protein (TIGR02142; EC 3.6.3.29; HMM-score: 181.8)Transport and binding proteins Other daunorubicin resistance ABC transporter, ATP-binding protein (TIGR01188; HMM-score: 180.9)Protein fate Protein and peptide secretion and trafficking lipoprotein releasing system, ATP-binding protein (TIGR02211; EC 3.6.3.-; HMM-score: 180.9)Transport and binding proteins Amino acids, peptides and amines polyamine ABC transporter, ATP-binding protein (TIGR01187; EC 3.6.3.31; HMM-score: 179.7)Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides LPS export ABC transporter ATP-binding protein (TIGR04406; HMM-score: 175.4)Transport and binding proteins Other LPS export ABC transporter ATP-binding protein (TIGR04406; HMM-score: 175.4)Transport and binding proteins Cations and iron carrying compounds nickel import ATP-binding protein NikD (TIGR02770; HMM-score: 173.6)ABC exporter ATP-binding subunit, DevA family (TIGR02982; HMM-score: 172.4)thiol reductant ABC exporter, CydD subunit (TIGR02857; HMM-score: 172.3)D-methionine ABC transporter, ATP-binding protein (TIGR02314; EC 3.6.3.-; HMM-score: 171.3)gliding motility-associated ABC transporter ATP-binding subunit GldA (TIGR03522; HMM-score: 166.3)Transport and binding proteins Amino acids, peptides and amines urea ABC transporter, ATP-binding protein UrtE (TIGR03410; HMM-score: 163.7)Transport and binding proteins Amino acids, peptides and amines urea ABC transporter, ATP-binding protein UrtD (TIGR03411; HMM-score: 161.5)Transport and binding proteins Cations and iron carrying compounds nickel import ATP-binding protein NikE (TIGR02769; EC 3.6.3.24; HMM-score: 160.7)Transport and binding proteins Amino acids, peptides and amines choline ABC transporter, ATP-binding protein (TIGR03415; HMM-score: 158.3)ectoine/hydroxyectoine ABC transporter, ATP-binding protein EhuA (TIGR03005; HMM-score: 156.8)Transport and binding proteins Unknown substrate anchored repeat-type ABC transporter, ATP-binding subunit (TIGR03771; HMM-score: 153.3)Protein fate Protein and peptide secretion and trafficking ABC-type bacteriocin transporter (TIGR01193; HMM-score: 151.2)Protein fate Protein modification and repair ABC-type bacteriocin transporter (TIGR01193; HMM-score: 151.2)Transport and binding proteins Other ABC-type bacteriocin transporter (TIGR01193; HMM-score: 151.2)thiol reductant ABC exporter, CydC subunit (TIGR02868; HMM-score: 151)Transport and binding proteins Other pigment precursor permease (TIGR00955; HMM-score: 150.6)proposed F420-0 ABC transporter, ATP-binding protein (TIGR03873; HMM-score: 149.6)Transport and binding proteins Carbohydrates, organic alcohols, and acids ABC transporter, ATP-binding subunit, PQQ-dependent alcohol dehydrogenase system (TIGR03864; HMM-score: 145.4)lantibiotic protection ABC transporter, ATP-binding subunit (TIGR03740; HMM-score: 144.8)Cellular processes Biosynthesis of natural products NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein (TIGR03796; HMM-score: 144.1)Transport and binding proteins Amino acids, peptides and amines NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein (TIGR03796; HMM-score: 144.1)Transport and binding proteins Anions nitrate ABC transporter, ATP-binding proteins C and D (TIGR01184; HMM-score: 136.6)Transport and binding proteins Other nitrate ABC transporter, ATP-binding proteins C and D (TIGR01184; HMM-score: 136.6)Cellular processes Other nodulation ABC transporter NodI (TIGR01288; HMM-score: 133.6)Transport and binding proteins Other nodulation ABC transporter NodI (TIGR01288; HMM-score: 133.6)Energy metabolism Methanogenesis methyl coenzyme M reductase system, component A2 (TIGR03269; HMM-score: 131.1)Protein fate Protein and peptide secretion and trafficking heme ABC exporter, ATP-binding protein CcmA (TIGR01189; EC 3.6.3.41; HMM-score: 129.9)Transport and binding proteins Other heme ABC exporter, ATP-binding protein CcmA (TIGR01189; EC 3.6.3.41; HMM-score: 129.9)Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides lipid A export permease/ATP-binding protein MsbA (TIGR02203; HMM-score: 129.4)Transport and binding proteins Other lipid A export permease/ATP-binding protein MsbA (TIGR02203; HMM-score: 129.4)Protein fate Protein and peptide secretion and trafficking type I secretion system ATPase (TIGR01842; HMM-score: 129.2)Protein fate Protein and peptide secretion and trafficking type I secretion system ATPase (TIGR01846; HMM-score: 121.4)Cellular processes Biosynthesis of natural products NHLM bacteriocin system ABC transporter, ATP-binding protein (TIGR03797; HMM-score: 115.3)Transport and binding proteins Amino acids, peptides and amines NHLM bacteriocin system ABC transporter, ATP-binding protein (TIGR03797; HMM-score: 115.3)Transport and binding proteins Carbohydrates, organic alcohols, and acids D-xylose ABC transporter, ATP-binding protein (TIGR02633; EC 3.6.3.17; HMM-score: 115)phosphonate C-P lyase system protein PhnL (TIGR02324; HMM-score: 112.5)Biosynthesis of cofactors, prosthetic groups, and carriers Other FeS assembly ATPase SufC (TIGR01978; HMM-score: 111.4)ABC transporter, permease/ATP-binding protein (TIGR02204; HMM-score: 107.6)Transport and binding proteins Other rim ABC transporter (TIGR01257; HMM-score: 105.3)Transport and binding proteins Other antigen peptide transporter 2 (TIGR00958; HMM-score: 101.9)Central intermediary metabolism Phosphorus compounds phosphonate C-P lyase system protein PhnK (TIGR02323; HMM-score: 101)Transport and binding proteins Amino acids, peptides and amines cyclic peptide transporter (TIGR01194; HMM-score: 99)Transport and binding proteins Other cyclic peptide transporter (TIGR01194; HMM-score: 99)ATP-binding cassette protein, ChvD family (TIGR03719; HMM-score: 93.4)Transport and binding proteins Other pleiotropic drug resistance family protein (TIGR00956; HMM-score: 92.8)Transport and binding proteins Other multi drug resistance-associated protein (MRP) (TIGR00957; HMM-score: 68.8)Transport and binding proteins Carbohydrates, organic alcohols, and acids glucan exporter ATP-binding protein (TIGR01192; EC 3.6.3.42; HMM-score: 62.2)Transport and binding proteins Anions cystic fibrosis transmembrane conductor regulator (CFTR) (TIGR01271; EC 3.6.3.49; HMM-score: 53.1)Transport and binding proteins Carbohydrates, organic alcohols, and acids peroxysomal long chain fatty acyl transporter (TIGR00954; HMM-score: 52.2)DNA metabolism DNA replication, recombination, and repair excinuclease ABC subunit A (TIGR00630; EC 3.1.25.-; HMM-score: 51.9)P-type DNA transfer ATPase VirB11 (TIGR02788; HMM-score: 19.1)DNA metabolism DNA replication, recombination, and repair DNA replication and repair protein RecF (TIGR00611; HMM-score: 17.4)Purines, pyrimidines, nucleosides, and nucleotides Salvage of nucleosides and nucleotides uridine kinase (TIGR00235; EC 2.7.1.48; HMM-score: 15.3)Unknown function General small GTP-binding protein domain (TIGR00231; HMM-score: 13.4)Central intermediary metabolism Sulfur metabolism adenylyl-sulfate kinase (TIGR00455; EC 2.7.1.25; HMM-score: 13.2)DNA metabolism DNA replication, recombination, and repair phage/plasmid primase, P4 family, C-terminal domain (TIGR01613; HMM-score: 12.8)Mobile and extrachromosomal element functions Prophage functions phage/plasmid primase, P4 family, C-terminal domain (TIGR01613; HMM-score: 12.8)Biosynthesis of cofactors, prosthetic groups, and carriers Pantothenate and coenzyme A dephospho-CoA kinase (TIGR00152; EC 2.7.1.24; HMM-score: 12.1)Central intermediary metabolism Phosphorus compounds phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN (TIGR02322; HMM-score: 11.9)helicase/secretion neighborhood ATPase (TIGR03819; HMM-score: 11.6)KaiC domain protein, AF_0351 family (TIGR03880; HMM-score: 10.9)DNA metabolism DNA replication, recombination, and repair exonuclease SbcC (TIGR00618; HMM-score: 10.2)Protein fate Protein and peptide secretion and trafficking type VII secretion protein EccCb (TIGR03925; HMM-score: 10.2)
- TheSEED :
- Methionine-regulated ECF transporter, duplicated ATPase component of energizing module MtsB
Amino Acids and Derivatives Lysine, threonine, methionine, and cysteine Methionine Biosynthesis Duplicated ATPase component MtsB of energizing module of methionine-regulated ECF transporterand 1 more - PFAM: P-loop_NTPase (CL0023) ABC_tran; ABC transporter (PF00005; HMM-score: 163.2)and 36 moreno clan defined DUF3744; ATP-binding cassette cobalt transporter (PF12558; HMM-score: 72.4)P-loop_NTPase (CL0023) AAA_21; AAA domain, putative AbiEii toxin, Type IV TA system (PF13304; HMM-score: 51.6)SMC_N; RecF/RecN/SMC N terminal domain (PF02463; HMM-score: 46.6)AAA_23; AAA domain (PF13476; HMM-score: 38.6)AAA_29; P-loop containing region of AAA domain (PF13555; HMM-score: 32.5)MMR_HSR1; 50S ribosome-binding GTPase (PF01926; HMM-score: 29.9)AAA_22; AAA domain (PF13401; HMM-score: 29.7)RsgA_GTPase; RsgA GTPase (PF03193; HMM-score: 25.7)AAA_16; AAA ATPase domain (PF13191; HMM-score: 23.4)AAA_33; AAA domain (PF13671; HMM-score: 23.4)Dynamin_N; Dynamin family (PF00350; HMM-score: 22)RNA_helicase; RNA helicase (PF00910; HMM-score: 21.2)Mg_chelatase; Magnesium chelatase, subunit ChlI (PF01078; HMM-score: 20.6)AAA; ATPase family associated with various cellular activities (AAA) (PF00004; HMM-score: 19.7)AAA_18; AAA domain (PF13238; HMM-score: 19.5)IstB_IS21; IstB-like ATP binding protein (PF01695; HMM-score: 18.3)T2SSE; Type II/IV secretion system protein (PF00437; HMM-score: 17.8)NACHT; NACHT domain (PF05729; HMM-score: 17.5)NB-ARC; NB-ARC domain (PF00931; HMM-score: 17)AAA_5; AAA domain (dynein-related subfamily) (PF07728; HMM-score: 17)DUF87; Domain of unknown function DUF87 (PF01935; HMM-score: 16)Sigma54_activat; Sigma-54 interaction domain (PF00158; HMM-score: 15.9)AAA_27; AAA domain (PF13514; HMM-score: 14.8)AAA_24; AAA domain (PF13479; HMM-score: 14.7)AAA_15; AAA ATPase domain (PF13175; HMM-score: 14.6)FtsK_SpoIIIE; FtsK/SpoIIIE family (PF01580; HMM-score: 14.2)Zeta_toxin; Zeta toxin (PF06414; HMM-score: 14.1)Septin; Septin (PF00735; HMM-score: 13.6)SbcCD_C; Putative exonuclease SbcCD, C subunit (PF13558; HMM-score: 13.3)AAA_13; AAA domain (PF13166; HMM-score: 12.7)PRK; Phosphoribulokinase / Uridine kinase family (PF00485; HMM-score: 12.5)ATP_bind_1; Conserved hypothetical ATP binding protein (PF03029; HMM-score: 12.3)AAA_25; AAA domain (PF13481; HMM-score: 12.1)ABC_ATPase; Predicted ATPase of the ABC class (PF09818; HMM-score: 11.5)AAA_30; AAA domain (PF13604; HMM-score: 11.3)Roc; Ras of Complex, Roc, domain of DAPkinase (PF08477; HMM-score: 8.5)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic Membrane
- Cytoplasmic Score: 0.01
- Cytoplasmic Membrane Score: 9.99
- Cellwall Score: 0
- Extracellular Score: 0
- Internal Helices: 0
- LocateP: Intracellular
- Prediction by SwissProt Classification: Cytoplasmic
- Pathway Prediction: No pathway
- Intracellular possibility: 1
- Signal peptide possibility: -1
- N-terminally Anchored Score: -1
- Predicted Cleavage Site: No CleavageSite
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.067465
- TAT(Tat/SPI): 0.001336
- LIPO(Sec/SPII): 0.020965
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MLVVGASGSGKSTFANCINGLIPFKTKGNITGELYINNQDATVSCLHDRSNVVGTVLQDTDGQFIGLTAAEDMAFLLENNCVEQDDMKKNVSYWAEKVGMIEHLNHRPQDLSGGQKQRVSLGGILIHRTPILILDEPLANLDPATGHETLRLLNNIHEETKSTMIIVEHRLEESLDDTFDRVLLFKDGKIIANTTPSDLLKSSKLKEAGIREPLYCTALKYAEVDVESIDNLANLRDVCMSEHVKFKVKKWIDETSANNDNKYKSEPLLELNEVCVQYSDYSNSVLNNVQLNVYRREMLSIVGHNGAGKSTLAKAICGFLDITGNIQFCNRGFNQLSISERSEFVGYVMQNPNHMISEKMIYDEVALGLRARGMKESDIKIRVENVLKICGLYAFRNWPIAALSYGQKKRVTIASVLVLNPEIIILDEPTAGQDFYHYNEIMSFLIELNRQGKTIIMITHDMHLLSEYSSRTVVLSKGQVVADTTPVLILNDKKICEIASLRQTSLFEMAEYIGISEPQKLVQLFINHDRKVRRQ
⊟Experimental data[edit | edit source]
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
- MicrobesOnline: SA2474 < SA2475 < SA2476
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
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