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NCBI: 10-JUN-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL2708 [new locus tag: SACOL_RS14165 ]
  • pan locus tag?: SAUPAN006440000
  • symbol: SACOL2708
  • pan gene symbol?: —
  • synonym:
  • product: ABC transporter ATP-binding protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SACOL2708 [new locus tag: SACOL_RS14165 ]
  • symbol: SACOL2708
  • product: ABC transporter ATP-binding protein
  • replicon: chromosome
  • strand: -
  • coordinates: 2780106..2781818
  • length: 1713
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    ATGACTGAACCAATTATCTCGTTCAAAGACTTTAGTTTTCAATATCATAGTCAAGCAACA
    CCTACATTACAGAATATAAATGTTGATATTTATCCAGGAGAAAAAGTATTAGTAGTTGGT
    GCTTCGGGTAGTGGTAAATCGACTTTTGCAAATTGCATAAACGGATTAATTCCATTTAAA
    ACTAAAGGTAACATAACTGGGGAACTATATATAAATAATCAAGATGCAACCGTTAGTTGT
    TTACATGATAGATCTAATGTTGTTGGTACAGTTTTACAAGATACAGATGGACAGTTCATA
    GGCTTAACAGCAGCTGAAGATATGGCCTTTTTATTAGAAAATAATTGTGTTGAACAAGAT
    GATATGAAGAAAAATGTAAGTTATTGGGCTGAAAAAGTTGGCATGATAGAACATTTAAAT
    CACCGACCGCAAGATTTATCTGGAGGTCAAAAACAACGCGTTTCATTAGGTGGTATATTA
    ATCCATCGTACGCCTATTTTAATATTGGATGAGCCACTGGCCAATTTAGATCCTGCGACA
    GGACATGAAACGCTGAGATTGTTAAACAATATTCATGAAGAAACAAAGTCAACGATGATT
    ATTGTCGAACATCGATTAGAAGAATCATTAGATGATACGTTTGATAGAGTTCTTCTTTTT
    AAAGATGGAAAAATCATCGCTAATACAACGCCTAGTGATTTGCTAAAATCATCTAAGCTT
    AAAGAAGCAGGCATACGTGAACCATTATACTGTACAGCGCTTAAATATGCAGAAGTAGAT
    GTCGAATCCATTGATAACTTAGCGAATTTACGTGACGTTTGTATGAGTGAACATGTTAAA
    TTTAAAGTGAAAAAATGGATAGATGAAACATCTGCAAATAATGATAATAAGTACAAATCT
    GAACCGCTATTAGAATTAAATGAGGTATGTGTTCAATATAGTGACTATAGTAATAGTGTA
    CTTAATAATGTTCAATTAAATGTTTATAGAAGAGAAATGCTTAGTATAGTTGGTCACAAT
    GGTGCCGGCAAATCAACACTTGCTAAAGCAATTTGTGGATTTTTAGATATAACAGGTAAT
    ATCCAATTTTGTAATAGGGGATTTAATCAATTGTCAATTAGCGAACGATCTGAATTCGTA
    GGTTATGTGATGCAAAATCCAAATCATATGATTTCTGAAAAAATGATTTACGATGAAGTA
    GCATTAGGGTTAAGAGCACGAGGTATGAAAGAATCAGATATAAAGATACGAGTAGAGAAT
    GTGCTCAAAATATGCGGACTTTATGCATTTCGGAATTGGCCAATTGCAGCTTTAAGCTAT
    GGTCAAAAAAAGAGGGTCACTATAGCATCTGTTTTAGTCTTAAATCCGGAAATAATCATA
    TTGGATGAACCGACTGCTGGTCAAGATTTCTATCATTATAATGAGATAATGTCATTTTTA
    ATTGAACTAAACAGACAGGGGAAGACGATTATTATGATTACGCATGATATGCATTTATTG
    TCTGAGTATAGTTCAAGAACAGTTGTATTATCAAAAGGTCAAGTCGTTGCTGATACCACG
    CCAGTATTGGTTTTAAATGATAAAAAAATCTGTGAGATTGCATCATTGAGACAAACATCG
    CTATTTGAAATGGCCGAATATATAGGGATTAGCGAGCCACAGAAATTAGTACAATTATTT
    ATTAACCATGATAGGAAGGTGAGACGCCAATGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1713

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SACOL2708 [new locus tag: SACOL_RS14165 ]
  • symbol: SACOL2708
  • description: ABC transporter ATP-binding protein
  • length: 570
  • theoretical pI: 6.01395
  • theoretical MW: 64144
  • GRAVY: -0.207193

⊟Function[edit | edit source]

  • reaction:
    EC 3.6.3.-?  ExPASy
  • TIGRFAM:
    Metabolism Transport and binding proteins Unknown substrate energy-coupling factor transporter ATPase (TIGR04520; EC 3.6.3.-; HMM-score: 387.3)
    Metabolism Transport and binding proteins Unknown substrate energy-coupling factor transporter ATPase (TIGR04521; EC 3.6.3.-; HMM-score: 338.7)
    and 88 more
    Cellular processes Cellular processes Cell division cell division ATP-binding protein FtsE (TIGR02673; HMM-score: 248.8)
    Metabolism Transport and binding proteins Cations and iron carrying compounds cobalt ABC transporter, ATP-binding protein (TIGR01166; HMM-score: 246.3)
    Cellular processes Cellular processes Pathogenesis type I secretion system ATPase (TIGR03375; HMM-score: 228.5)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type I secretion system ATPase (TIGR03375; HMM-score: 228.5)
    Metabolism Transport and binding proteins Anions sulfate ABC transporter, ATP-binding protein (TIGR00968; EC 3.6.3.25; HMM-score: 215.7)
    Metabolism Transport and binding proteins Amino acids, peptides and amines putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein (TIGR03265; HMM-score: 211.7)
    Metabolism Transport and binding proteins Anions phosphate ABC transporter, ATP-binding protein (TIGR00972; EC 3.6.3.27; HMM-score: 208)
    Metabolism Transport and binding proteins Anions phosphonate ABC transporter, ATP-binding protein (TIGR02315; EC 3.6.3.28; HMM-score: 207.3)
    Cellular processes Cellular processes Toxin production and resistance putative bacteriocin export ABC transporter, lactococcin 972 group (TIGR03608; HMM-score: 202.5)
    Metabolism Transport and binding proteins Unknown substrate putative bacteriocin export ABC transporter, lactococcin 972 group (TIGR03608; HMM-score: 202.5)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking lipoprotein releasing system, ATP-binding protein (TIGR02211; EC 3.6.3.-; HMM-score: 198.9)
    2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT (TIGR03258; HMM-score: 198.6)
    thiol reductant ABC exporter, CydD subunit (TIGR02857; HMM-score: 196.5)
    Metabolism Transport and binding proteins Other thiamine ABC transporter, ATP-binding protein (TIGR01277; EC 3.6.3.-; HMM-score: 196)
    Metabolism Transport and binding proteins Amino acids, peptides and amines glycine betaine/L-proline transport ATP binding subunit (TIGR01186; HMM-score: 195)
    ABC exporter ATP-binding subunit, DevA family (TIGR02982; HMM-score: 191.3)
    Metabolism Transport and binding proteins Other daunorubicin resistance ABC transporter, ATP-binding protein (TIGR01188; HMM-score: 188.4)
    Cell structure Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides LPS export ABC transporter ATP-binding protein (TIGR04406; HMM-score: 185.8)
    Metabolism Transport and binding proteins Other LPS export ABC transporter ATP-binding protein (TIGR04406; HMM-score: 185.8)
    Metabolism Transport and binding proteins Anions molybdate ABC transporter, ATP-binding protein (TIGR02142; EC 3.6.3.29; HMM-score: 185.6)
    D-methionine ABC transporter, ATP-binding protein (TIGR02314; EC 3.6.3.-; HMM-score: 180.9)
    Metabolism Transport and binding proteins Cations and iron carrying compounds nickel import ATP-binding protein NikD (TIGR02770; HMM-score: 179.6)
    Metabolism Transport and binding proteins Amino acids, peptides and amines polyamine ABC transporter, ATP-binding protein (TIGR01187; EC 3.6.3.31; HMM-score: 178.5)
    thiol reductant ABC exporter, CydC subunit (TIGR02868; HMM-score: 177.1)
    Metabolism Transport and binding proteins Cations and iron carrying compounds nickel import ATP-binding protein NikE (TIGR02769; EC 3.6.3.24; HMM-score: 177)
    Metabolism Transport and binding proteins Amino acids, peptides and amines urea ABC transporter, ATP-binding protein UrtE (TIGR03410; HMM-score: 175.1)
    gliding motility-associated ABC transporter ATP-binding subunit GldA (TIGR03522; HMM-score: 174.4)
    Metabolism Transport and binding proteins Amino acids, peptides and amines urea ABC transporter, ATP-binding protein UrtD (TIGR03411; HMM-score: 172.2)
    Cellular processes Cellular processes Biosynthesis of natural products NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein (TIGR03796; HMM-score: 172)
    Metabolism Transport and binding proteins Amino acids, peptides and amines NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein (TIGR03796; HMM-score: 172)
    ectoine/hydroxyectoine ABC transporter, ATP-binding protein EhuA (TIGR03005; HMM-score: 171.6)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking ABC-type bacteriocin transporter (TIGR01193; HMM-score: 170.1)
    Genetic information processing Protein fate Protein modification and repair ABC-type bacteriocin transporter (TIGR01193; HMM-score: 170.1)
    Metabolism Transport and binding proteins Other ABC-type bacteriocin transporter (TIGR01193; HMM-score: 170.1)
    Metabolism Transport and binding proteins Amino acids, peptides and amines choline ABC transporter, ATP-binding protein (TIGR03415; HMM-score: 166.2)
    Cell structure Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides lipid A export permease/ATP-binding protein MsbA (TIGR02203; HMM-score: 159.2)
    Metabolism Transport and binding proteins Other lipid A export permease/ATP-binding protein MsbA (TIGR02203; HMM-score: 159.2)
    Metabolism Transport and binding proteins Other pigment precursor permease (TIGR00955; HMM-score: 159.1)
    proposed F420-0 ABC transporter, ATP-binding protein (TIGR03873; HMM-score: 158)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids ABC transporter, ATP-binding subunit, PQQ-dependent alcohol dehydrogenase system (TIGR03864; HMM-score: 157.8)
    Metabolism Transport and binding proteins Unknown substrate anchored repeat-type ABC transporter, ATP-binding subunit (TIGR03771; HMM-score: 156.6)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type I secretion system ATPase (TIGR01846; HMM-score: 152.7)
    lantibiotic protection ABC transporter, ATP-binding subunit (TIGR03740; HMM-score: 152.5)
    Metabolism Transport and binding proteins Anions nitrate ABC transporter, ATP-binding proteins C and D (TIGR01184; HMM-score: 148.7)
    Metabolism Transport and binding proteins Other nitrate ABC transporter, ATP-binding proteins C and D (TIGR01184; HMM-score: 148.7)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type I secretion system ATPase (TIGR01842; HMM-score: 148.4)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking heme ABC exporter, ATP-binding protein CcmA (TIGR01189; EC 3.6.3.41; HMM-score: 142.8)
    Metabolism Transport and binding proteins Other heme ABC exporter, ATP-binding protein CcmA (TIGR01189; EC 3.6.3.41; HMM-score: 142.8)
    Cellular processes Cellular processes Biosynthesis of natural products NHLM bacteriocin system ABC transporter, ATP-binding protein (TIGR03797; HMM-score: 142.1)
    Metabolism Transport and binding proteins Amino acids, peptides and amines NHLM bacteriocin system ABC transporter, ATP-binding protein (TIGR03797; HMM-score: 142.1)
    Metabolism Energy metabolism Methanogenesis methyl coenzyme M reductase system, component A2 (TIGR03269; HMM-score: 141.7)
    Cellular processes Cellular processes Other nodulation ABC transporter NodI (TIGR01288; HMM-score: 137.3)
    Metabolism Transport and binding proteins Other nodulation ABC transporter NodI (TIGR01288; HMM-score: 137.3)
    ABC transporter, permease/ATP-binding protein (TIGR02204; HMM-score: 134.4)
    Metabolism Transport and binding proteins Other antigen peptide transporter 2 (TIGR00958; HMM-score: 130.5)
    phosphonate C-P lyase system protein PhnL (TIGR02324; HMM-score: 129.4)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids D-xylose ABC transporter, ATP-binding protein (TIGR02633; EC 3.6.3.17; HMM-score: 127.8)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Other FeS assembly ATPase SufC (TIGR01978; HMM-score: 126.9)
    Metabolism Central intermediary metabolism Phosphorus compounds phosphonate C-P lyase system protein PhnK (TIGR02323; HMM-score: 115.6)
    Metabolism Transport and binding proteins Other rim ABC transporter (TIGR01257; HMM-score: 113.8)
    Metabolism Transport and binding proteins Amino acids, peptides and amines cyclic peptide transporter (TIGR01194; HMM-score: 111.1)
    Metabolism Transport and binding proteins Other cyclic peptide transporter (TIGR01194; HMM-score: 111.1)
    ATP-binding cassette protein, ChvD family (TIGR03719; HMM-score: 106.8)
    Metabolism Transport and binding proteins Other pleiotropic drug resistance family protein (TIGR00956; HMM-score: 102.7)
    Metabolism Transport and binding proteins Other multi drug resistance-associated protein (MRP) (TIGR00957; HMM-score: 94.5)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids glucan exporter ATP-binding protein (TIGR01192; EC 3.6.3.42; HMM-score: 76.3)
    Metabolism Transport and binding proteins Anions cystic fibrosis transmembrane conductor regulator (CFTR) (TIGR01271; EC 3.6.3.49; HMM-score: 68)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair excinuclease ABC subunit A (TIGR00630; EC 3.1.25.-; HMM-score: 65.2)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids peroxysomal long chain fatty acyl transporter (TIGR00954; HMM-score: 62.6)
    P-type DNA transfer ATPase VirB11 (TIGR02788; HMM-score: 23)
    Unknown function General small GTP-binding protein domain (TIGR00231; HMM-score: 16.9)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair DNA replication and repair protein RecF (TIGR00611; HMM-score: 16)
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Salvage of nucleosides and nucleotides uridine kinase (TIGR00235; EC 2.7.1.48; HMM-score: 15.8)
    Genetic information processing Protein synthesis Other ribosome biogenesis GTPase YqeH (TIGR03597; HMM-score: 15.6)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type VII secretion protein EccCb (TIGR03925; HMM-score: 14.5)
    Metabolism Central intermediary metabolism Sulfur metabolism adenylyl-sulfate kinase (TIGR00455; EC 2.7.1.25; HMM-score: 13.9)
    Cellular processes Cellular processes Conjugation P-type conjugative transfer ATPase TrbB (TIGR02782; HMM-score: 13.6)
    Metabolism Central intermediary metabolism Phosphorus compounds phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN (TIGR02322; HMM-score: 13.2)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair DnaA regulatory inactivator Hda (TIGR03420; HMM-score: 13.2)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair phage/plasmid primase, P4 family, C-terminal domain (TIGR01613; HMM-score: 13)
    Genetic information processing Mobile and extrachromosomal element functions Prophage functions phage/plasmid primase, P4 family, C-terminal domain (TIGR01613; HMM-score: 13)
    helicase/secretion neighborhood ATPase (TIGR03819; HMM-score: 12.9)
    KaiC domain protein, AF_0351 family (TIGR03880; HMM-score: 12.4)
    Genetic information processing Protein synthesis tRNA and rRNA base modification tRNA threonylcarbamoyl adenosine modification protein YjeE (TIGR00150; HMM-score: 12)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Pantothenate and coenzyme A dephospho-CoA kinase (TIGR00152; EC 2.7.1.24; HMM-score: 12)
    sugar-phosphate isomerase, RpiB/LacA/LacB family (TIGR00689; EC 5.3.1.-; HMM-score: 12)
    Genetic information processing Transcription RNA processing polynucleotide kinase-phosphatase (TIGR04075; HMM-score: 11.6)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair exonuclease SbcC (TIGR00618; HMM-score: 10.3)
  • TheSEED  :
    • Duplicated ATPase component MtsB of energizing module of methionine-regulated ECF transporter
    Amino Acids and Derivatives Lysine, threonine, methionine, and cysteine Methionine Biosynthesis  Duplicated ATPase component MtsB of energizing module of methionine-regulated ECF transporter
    and 1 more
    Membrane Transport Membrane Transport - no subcategory ECF class transporters  Duplicated ATPase component MtsB of energizing module of methionine-regulated ECF transporter
  • PFAM:
    P-loop_NTPase (CL0023) ABC_tran; ABC transporter (PF00005; HMM-score: 179.9)
    and 46 more
    no clan defined DUF3744; ATP-binding cassette cobalt transporter (PF12558; HMM-score: 72.3)
    P-loop_NTPase (CL0023) AAA_21; AAA domain, putative AbiEii toxin, Type IV TA system (PF13304; HMM-score: 50.9)
    SMC_N; RecF/RecN/SMC N terminal domain (PF02463; HMM-score: 48.1)
    AAA_23; AAA domain (PF13476; HMM-score: 39.8)
    AAA_29; P-loop containing region of AAA domain (PF13555; HMM-score: 35.8)
    MMR_HSR1; 50S ribosome-binding GTPase (PF01926; HMM-score: 31.7)
    AAA_22; AAA domain (PF13401; HMM-score: 29.5)
    RsgA_GTPase; RsgA GTPase (PF03193; HMM-score: 28.7)
    AAA_16; AAA ATPase domain (PF13191; HMM-score: 25.2)
    AAA_33; AAA domain (PF13671; HMM-score: 24.1)
    IstB_IS21; IstB-like ATP binding protein (PF01695; HMM-score: 23.5)
    Dynamin_N; Dynamin family (PF00350; HMM-score: 22.9)
    Mg_chelatase; Magnesium chelatase, subunit ChlI (PF01078; HMM-score: 22.8)
    RNA_helicase; RNA helicase (PF00910; HMM-score: 21.4)
    AAA_18; AAA domain (PF13238; HMM-score: 20.6)
    Sigma54_activat; Sigma-54 interaction domain (PF00158; HMM-score: 19.8)
    T2SSE; Type II/IV secretion system protein (PF00437; HMM-score: 19.8)
    AAA; ATPase family associated with various cellular activities (AAA) (PF00004; HMM-score: 18.9)
    NACHT; NACHT domain (PF05729; HMM-score: 18.5)
    AAA_5; AAA domain (dynein-related subfamily) (PF07728; HMM-score: 18.3)
    AAA_15; AAA ATPase domain (PF13175; HMM-score: 18.3)
    AAA_25; AAA domain (PF13481; HMM-score: 17.9)
    DUF87; Domain of unknown function DUF87 (PF01935; HMM-score: 17.8)
    NB-ARC; NB-ARC domain (PF00931; HMM-score: 17.2)
    FtsK_SpoIIIE; FtsK/SpoIIIE family (PF01580; HMM-score: 17.2)
    AAA_24; AAA domain (PF13479; HMM-score: 16.4)
    Zeta_toxin; Zeta toxin (PF06414; HMM-score: 15.4)
    AAA_27; AAA domain (PF13514; HMM-score: 15.1)
    ATPase; KaiC (PF06745; HMM-score: 14.9)
    G-alpha; G-protein alpha subunit (PF00503; HMM-score: 14.6)
    Septin; Septin (PF00735; HMM-score: 14.6)
    TsaE; Threonylcarbamoyl adenosine biosynthesis protein TsaE (PF02367; HMM-score: 14.4)
    Sigma54_activ_2; Sigma-54 interaction domain (PF14532; HMM-score: 14.2)
    AAA_13; AAA domain (PF13166; HMM-score: 13.6)
    DUF815; Protein of unknown function (DUF815) (PF05673; HMM-score: 13.3)
    SbcCD_C; Putative exonuclease SbcCD, C subunit (PF13558; HMM-score: 13.1)
    NTPase_1; NTPase (PF03266; HMM-score: 13)
    APS_kinase; Adenylylsulphate kinase (PF01583; HMM-score: 12.9)
    ArgK; ArgK protein (PF03308; HMM-score: 12.7)
    PRK; Phosphoribulokinase / Uridine kinase family (PF00485; HMM-score: 12.4)
    PduV-EutP; Ethanolamine utilisation - propanediol utilisation (PF10662; HMM-score: 12.2)
    ATP_bind_1; Conserved hypothetical ATP binding protein (PF03029; HMM-score: 12.1)
    AIG1; AIG1 family (PF04548; HMM-score: 11.9)
    AAA_30; AAA domain (PF13604; HMM-score: 11.9)
    Roc; Ras of Complex, Roc, domain of DAPkinase (PF08477; HMM-score: 11.6)
    ABC_ATPase; Predicted ATPase of the ABC class (PF09818; HMM-score: 11.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.17
    • Cytoplasmic Membrane Score: 9.51
    • Cellwall Score: 0.16
    • Extracellular Score: 0.15
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.059546
    • TAT(Tat/SPI): 0.001419
    • LIPO(Sec/SPII): 0.003022
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MTEPIISFKDFSFQYHSQATPTLQNINVDIYPGEKVLVVGASGSGKSTFANCINGLIPFKTKGNITGELYINNQDATVSCLHDRSNVVGTVLQDTDGQFIGLTAAEDMAFLLENNCVEQDDMKKNVSYWAEKVGMIEHLNHRPQDLSGGQKQRVSLGGILIHRTPILILDEPLANLDPATGHETLRLLNNIHEETKSTMIIVEHRLEESLDDTFDRVLLFKDGKIIANTTPSDLLKSSKLKEAGIREPLYCTALKYAEVDVESIDNLANLRDVCMSEHVKFKVKKWIDETSANNDNKYKSEPLLELNEVCVQYSDYSNSVLNNVQLNVYRREMLSIVGHNGAGKSTLAKAICGFLDITGNIQFCNRGFNQLSISERSEFVGYVMQNPNHMISEKMIYDEVALGLRARGMKESDIKIRVENVLKICGLYAFRNWPIAALSYGQKKRVTIASVLVLNPEIIILDEPTAGQDFYHYNEIMSFLIELNRQGKTIIMITHDMHLLSEYSSRTVVLSKGQVVADTTPVLVLNDKKICEIASLRQTSLFEMAEYIGISEPQKLVQLFINHDRKVRRQ

⊟Experimental data[edit | edit source]

  • experimentally validated: PeptideAtlas
  • protein localization: Cytoplasmic [1] [2] [3]
  • quantitative data / protein copy number per cell: 89 [4]
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Dörte Becher, Kristina Hempel, Susanne Sievers, Daniela Zühlke, Jan Pané-Farré, Andreas Otto, Stephan Fuchs, Dirk Albrecht, Jörg Bernhardt, Susanne Engelmann, Uwe Völker, Jan Maarten van Dijl, Michael Hecker
    A proteomic view of an important human pathogen--towards the quantification of the entire Staphylococcus aureus proteome.
    PLoS One: 2009, 4(12);e8176
    [PubMed:19997597] [WorldCat.org] [DOI] (I e)
  2. ↑ Kristina Hempel, Florian-Alexander Herbst, Martin Moche, Michael Hecker, Dörte Becher
    Quantitative proteomic view on secreted, cell surface-associated, and cytoplasmic proteins of the methicillin-resistant human pathogen Staphylococcus aureus under iron-limited conditions.
    J Proteome Res: 2011, 10(4);1657-66
    [PubMed:21323324] [WorldCat.org] [DOI] (I p)
  3. ↑ Andreas Otto, Jan Maarten van Dijl, Michael Hecker, Dörte Becher
    The Staphylococcus aureus proteome.
    Int J Med Microbiol: 2014, 304(2);110-20
    [PubMed:24439828] [WorldCat.org] [DOI] (I p)
  4. ↑ Daniela Zühlke, Kirsten Dörries, Jörg Bernhardt, Sandra Maaß, Jan Muntel, Volkmar Liebscher, Jan Pané-Farré, Katharina Riedel, Michael Lalk, Uwe Völker, Susanne Engelmann, Dörte Becher, Stephan Fuchs, Michael Hecker
    Costs of life - Dynamics of the protein inventory of Staphylococcus aureus during anaerobiosis.
    Sci Rep: 2016, 6;28172
    [PubMed:27344979] [WorldCat.org] [DOI] (I e)

⊟Relevant publications[edit | edit source]

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