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NCBI: 10-JUN-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL0751 [new locus tag: SACOL_RS03855 ]
  • pan locus tag?: SAUPAN002575000
  • symbol: SACOL0751
  • pan gene symbol?: —
  • synonym:
  • product: deoxyribodipyrimidine photolyase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SACOL0751 [new locus tag: SACOL_RS03855 ]
  • symbol: SACOL0751
  • product: deoxyribodipyrimidine photolyase
  • replicon: chromosome
  • strand: +
  • coordinates: 772720..774093
  • length: 1374
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    ATGGCAATTGCTGTGTTATTAAATCGAATGTTTCGAATGGAACACAATCCATTATTTGAA
    TATATTTATCAACAAAAAGAAGACATTGATGCATGTTATTTTATCATTCCGGAAGAGGAC
    ATGTCTTCAGCTTCTGATTTGAAAGCACAGTTTTATCGCGGTACTTTGCAGCGCTTTTAC
    CAATCGTTGCACGCAGAAAAGCTTACACCTTATGTTATGTCTTATGACGATATCATTTCA
    TTTTGTAAAGAAAACAATATCTCTGAAGTAGTGACTGCGGGTGATATTATGAGTTATCAT
    CTTGAAGAATATGATATTTTACATCAACGTTCTTTATTCAATGAAGCACGCATTGCCGTT
    ACTTTGATACGTGGGAATCATTACTTTAAAGCGAGTAAAACAATGAATCAACAAGGGGAG
    CCATACAATGTTTTTACTAGTTTCTATAAAAAATGGCGACCTTACTTGAGGCATAGAGAC
    GTATATCACTATGATTTAAAATCATTCGAAGACTTTGTCATTGCATCACCTGATGATTTA
    GTGTTTGATGACATAGCATTTGGATCCTCACAAATAATTGAACAGAATAAATGGCAACAT
    TTTTTAGATCAAGATATACAGAATTACGAAAGCGGAAGAGACTATTTACCTGAAGTATTA
    ACAAGTCAGCTAAGTGTTGCTTTAGCATATGGATTATTAGATATTATTGAAATTTTTAAT
    GATTTATTGGCGCGTTATGATGAAGATGAGGCAAACTATGAAGCATTTATACGTGAACTC
    ATTTTTAGAGAATTTTATTATGTGTTAATGACACAGTATCCTGAAACCTCATACCAAGCT
    TTCAAACCTAAATATCGACAGATAAAATGGTCGCAAAATGAAGCGGATTTTAATGCATGG
    TGCGAAGGGCAAACAGGATTTCCAATCATTGATGCAGCAATAATGGAATTGACACAAACT
    GGTTTTATGCATAATCGAATGAGAATGGTTGTGTCGCAATTTTTAACCAAAGATTTATTT
    ATAGATTGGACATGGGGAGAAAAATTCTTTAGAAAGCACCTTATTGACTATGATGCAGCA
    TCAAATATTCATGGATGGCAATGGTCTGCTTCTACAGGTACGGATGCAGTGCCGTATTTT
    AGAATGTTTAATCCAATAAGACAGAGTGAACGCTTTGATGCTAAAGCTTTGTATATCAAA
    ACATATCTTCCGATTTTTAATCAAATTGATGCAAAATATTTGCATGATACACAACGCAAT
    GAGTCCAACCTTTTTGAACAGGGGATTGAATTAGGTAGTCATTATCCAAGACAAATGGTA
    GATCATCAAGAAAAACGTACACAAGTTTTAGCTACATTTAAAGCGCTAGACTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1374

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SACOL0751 [new locus tag: SACOL_RS03855 ]
  • symbol: SACOL0751
  • description: deoxyribodipyrimidine photolyase
  • length: 457
  • theoretical pI: 4.9108
  • theoretical MW: 54369.9
  • GRAVY: -0.449015

⊟Function[edit | edit source]

  • ⊞TIGRFAM:
    Genetic information processing DNA metabolism DNA replication, recombination, and repair deoxyribodipyrimidine photo-lyase, 8-HDF type (TIGR03556; EC 4.1.99.3; HMM-score: 249.3)
    and 4 more
    cryptochrome, plant family (TIGR02766; HMM-score: 149.8)
    Cellular processes Cellular processes Adaptations to atypical conditions cryptochrome, DASH family (TIGR02765; HMM-score: 149.2)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair deoxyribodipyrimidine photolyase (TIGR00591; EC 4.1.99.3; HMM-score: 17.7)
    Unknown function Enzymes of unknown specificity putative phosphoesterase (TIGR00024; EC 3.1.-.-; HMM-score: 13.9)
  • TheSEED  :
    • Deoxyribodipyrimidine photolyase (EC 4.1.99.3)
    DNA Metabolism DNA repair DNA repair, bacterial photolyase  Deoxyribodipyrimidine photolyase (EC 4.1.99.3)
  • ⊞PFAM:
    no clan defined FAD_binding_7; FAD binding domain of DNA photolyase (PF03441; HMM-score: 256.9)
    and 2 more
    HUP (CL0039) DNA_photolyase; DNA photolyase (PF00875; HMM-score: 40.4)
    Calcineurin (CL0163) Metallophos; Calcineurin-like phosphoesterase (PF00149; HMM-score: 15.2)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • ⊞PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • ⊞DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9929
    • Cytoplasmic Membrane Score: 0.0053
    • Cell wall & surface Score: 0.0001
    • Extracellular Score: 0.0017
  • ⊞LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • ⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.001389
    • TAT(Tat/SPI): 0.000095
    • LIPO(Sec/SPII): 0.000339
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MAIAVLLNRMFRMEHNPLFEYIYQQKEDIDACYFIIPEEDMSSASDLKAQFYRGTLQRFYQSLHAEKLTPYVMSYDDIISFCKENNISEVVTAGDIMSYHLEEYDILHQRSLFNEARIAVTLIRGNHYFKASKTMNQQGEPYNVFTSFYKKWRPYLRHRDVYHYDLKSFEDFVIASPDDLVFDDIAFGSSQIIEQNKWQHFLDQDIQNYESGRDYLPEVLTSQLSVALAYGLLDIIEIFNDLLARYDEDEANYEAFIRELIFREFYYVLMTQYPETSYQAFKPKYRQIKWSQNEADFNAWCEGQTGFPIIDAAIMELTQTGFMHNRMRMVVSQFLTKDLFIDWTWGEKFFRKHLIDYDAASNIHGWQWSASTGTDAVPYFRMFNPIRQSERFDAKALYIKTYLPIFNQIDAKYLHDTQRNESNLFEQGIELGSHYPRQMVDHQEKRTQVLATFKALD

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization: Cytoplasmic [1] [2]
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊞Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊞Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Kristina Hempel, Florian-Alexander Herbst, Martin Moche, Michael Hecker, Dörte Becher
    Quantitative proteomic view on secreted, cell surface-associated, and cytoplasmic proteins of the methicillin-resistant human pathogen Staphylococcus aureus under iron-limited conditions.
    J Proteome Res: 2011, 10(4);1657-66
    [PubMed:21323324] [WorldCat.org] [DOI] (I p)
  2. ↑ Andreas Otto, Jan Maarten van Dijl, Michael Hecker, Dörte Becher
    The Staphylococcus aureus proteome.
    Int J Med Microbiol: 2014, 304(2);110-20
    [PubMed:24439828] [WorldCat.org] [DOI] (I p)

⊟Relevant publications[edit | edit source]

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