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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL_RS06870 [old locus tag: SACOL1349 ]
  • pan locus tag?: SAUPAN003680000
  • symbol: SACOL_RS06870
  • pan gene symbol?: —
  • synonym:
  • product: low specificity L-threonine aldolase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SACOL_RS06870 [old locus tag: SACOL1349 ]
  • symbol: SACOL_RS06870
  • product: low specificity L-threonine aldolase
  • replicon: chromosome
  • strand: -
  • coordinates: 1356182..1357207
  • length: 1026
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_002951 (1356182..1357207) NCBI
  • BioCyc: SACOL_RS06870 BioCyc
  • MicrobesOnline: see SACOL1349

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    GTGATTTCATTCGAAAATGATTATTTAGAAGGTGCTCATGAAAAAGTATTAAAACGATTA
    GTAGATACAAATCTTGTACAAGCTTCGGGATATGGCTTTGATCAATTCACAGCTCAGGCA
    ATTGAAAAGATTAAAGATACAATTGACTGTCCAAATGCTACAATTCGTTTTTTAGTAGGT
    GGAACACAAACCAATCAGGTTGTTATTAATTCAATGTTAGAAAGTTACGAAGGGGTCATT
    TCAGCAGACACTGGTCATGTTGCTGTGCATGAGGGCGGTGCAATTGAATATAGTGGACAT
    AAAGTAATTACTATACCCTCTAAGGAAGGAAAAGTTAGTGCTTCAGATGTTGAAACTTAC
    ATGGAGACATTTAAAAGTGATTTTAAAAAGGACCATATGGTATTCCCAGGAATGGTATAT
    ATTTCTCATCCTACAGAATATGGCACATTATACTCTAAATCAGAATTGGAAGAGTTATGC
    AAAGTATGTAAGCAATATCAGCTTCCATTATTTATGGATGGTGCACGATTAGGGTATGGA
    TTGATGAGTGACCAATCAGATATGACTATTAAAGACATCGCTAAATATTGTGATGTATTT
    TATATAGGTGGTACGAAGATAGGTGCATTATGCGGGGAAGCCATTGTTTTTACGAAAAAT
    AATGAACCGAAACAATTTACCACTCGAATCAAGCATCACGGTGCCCTTTTAGCAAAAGGA
    CGGTTAACAGGCATACAATTTTTAGAATTATTTACGGACAATTTATATTTTAATATAAGC
    AGACATGCTATCGAAATGGCAAATAAGATGAAAGACGGGTTTAAAAATAAAGGCTATCGT
    CTTTACTTTGATTCTCCAACCAATCAACAATTTTTTATTTTAAGTAACGAGAAAATAGCA
    GAGTTAGAACAAAAAGTTAAATTTGCTGTTTGGGAAAAATACGATGATCAACATCGTGTT
    GTTAGATTCGCAACCAGTTGGGCGACAACCGAAGAAAATTTAAATAAACTATTAGAATTA
    ATCTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1026

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SACOL_RS06870 [old locus tag: SACOL1349 ]
  • symbol: SACOL_RS06870
  • description: low specificity L-threonine aldolase
  • length: 341
  • theoretical pI: 6.18837
  • theoretical MW: 38633.8
  • GRAVY: -0.293548

⊟Function[edit | edit source]

  • TIGRFAM:
    O-phospho-L-seryl-tRNA:Cys-tRNA synthase (TIGR02539; EC 2.5.1.73; HMM-score: 22.3)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Other tyrosine decarboxylase MnfA (TIGR03812; EC 4.1.1.25; HMM-score: 20.3)
    and 3 more
    cysteine desulfurase NifS (TIGR03402; EC 2.8.1.7; HMM-score: 16.7)
    aminotransferase, LLPSF_NHT_00031 family (TIGR04181; HMM-score: 12.3)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Other coenzyme PQQ biosynthesis protein PqqD (TIGR03859; HMM-score: 12.1)
  • TheSEED: see SACOL1349
  • PFAM:
    PLP_aminotran (CL0061) Beta_elim_lyase; Beta-eliminating lyase (PF01212; HMM-score: 100.1)
    and 5 more
    Aminotran_1_2; Aminotransferase class I and II (PF00155; HMM-score: 25.3)
    Aminotran_5; Aminotransferase class-V (PF00266; HMM-score: 22.7)
    SepSecS; O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS (PF05889; HMM-score: 14.1)
    Pyridoxal_deC; Pyridoxal-dependent decarboxylase conserved domain (PF00282; HMM-score: 11.3)
    GHD (CL0369) DUF1945; Domain of unknown function (DUF1945) (PF09178; HMM-score: 8.7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.02291
    • TAT(Tat/SPI): 0.001091
    • LIPO(Sec/SPII): 0.000955
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MISFENDYLEGAHEKVLKRLVDTNLVQASGYGFDQFTAQAIEKIKDTIDCPNATIRFLVGGTQTNQVVINSMLESYEGVISADTGHVAVHEGGAIEYSGHKVITIPSKEGKVSASDVETYMETFKSDFKKDHMVFPGMVYISHPTEYGTLYSKSELEELCKVCKQYQLPLFMDGARLGYGLMSDQSDMTIKDIAKYCDVFYIGGTKIGALCGEAIVFTKNNEPKQFTTRIKHHGALLAKGRLTGIQFLELFTDNLYFNISRHAIEMANKMKDGFKNKGYRLYFDSPTNQQFFILSNEKIAELEQKVKFAVWEKYDDQHRVVRFATSWATTEENLNKLLELI

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization: see SACOL1349
  • quantitative data / protein copy number per cell: see SACOL1349
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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