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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL_RS13100 [old locus tag: SACOL2500 ]
  • pan locus tag?: SAUPAN006089000
  • symbol: SACOL_RS13100
  • pan gene symbol?: —
  • synonym:
  • product: (deoxy)nucleoside triphosphate pyrophosphohydrolase

⊟Additional information (user-provided)[edit | edit source]

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SACOL_RS13100 [old locus tag: SACOL2500 ]
  • symbol: SACOL_RS13100
  • product: (deoxy)nucleoside triphosphate pyrophosphohydrolase
  • replicon: chromosome
  • strand: -
  • coordinates: 2554002..2554394
  • length: 393
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_002951 (2554002..2554394) NCBI
  • BioCyc: SACOL_RS13100 BioCyc
  • MicrobesOnline: see SACOL2500

⊟Phenotype[edit | edit source]

⊟Additional information (user-provided)[edit | edit source]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    ATGAAAAAAGTAATCAATGTAGTAGGAGCTATTATTTTTTCTGATAACAAAATTCTTTGT
    GCACAGAGAAGTGAAAAAATGAGTCTGCCTTTAATGTGGGAATTTCCTGGCGGTAAGGTT
    GAAAAGAATGAAACTGAAAAAGACGCTTTGATTAGAGAAATTAGAGAAGAAATGAAATGT
    GATTTAATTGTTGGAGACAAAGTTATAACTACAGAACATGAATATGATTTTGGAATTGTT
    AGGTTAACAACATACAAATGTACTTTAAACAAAGAGTTACCAACTCTAACTGAACATAAG
    AGTATTGAATGGTTGTCAATAAACGAACTTGATAAATTAAATTGGGCCCCAGCGGATATA
    CCAGCCGTTAATAAAATTATGACTGAGGGATAA
    60
    120
    180
    240
    300
    360
    393


⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SACOL_RS13100 [old locus tag: SACOL2500 ]
  • symbol: SACOL_RS13100
  • description: (deoxy)nucleoside triphosphate pyrophosphohydrolase
  • length: 130
  • theoretical pI: 5.03646
  • theoretical MW: 14894.3
  • GRAVY: -0.277692

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing DNA metabolism DNA replication, recombination, and repair mutator mutT protein (TIGR00586; EC 3.6.1.-; HMM-score: 74.6)
    and 1 more
    Genetic information processing DNA metabolism DNA replication, recombination, and repair nucleoside triphosphatase YtkD (TIGR02705; EC 3.6.1.-; HMM-score: 30.3)
  • TheSEED: data available for N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    NUDIX (CL0261) NUDIX_4; NUDIX domain (PF14815; HMM-score: 62.8)
    NUDIX; NUDIX domain (PF00293; HMM-score: 57.8)
    and 2 more
    Nudt16-like; U8 snoRNA-decapping enzyme-like (PF22327; HMM-score: 16.5)
    GST_C (CL0497) GST_C; Glutathione S-transferase, C-terminal domain (PF00043; HMM-score: 12.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9938
    • Cytoplasmic Membrane Score: 0.0002
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.006
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.054851
    • TAT(Tat/SPI): 0.000904
    • LIPO(Sec/SPII): 0.028085
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Additional information (user-provided)[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MKKVINVVGAIIFSDNKILCAQRSEKMSLPLMWEFPGGKVEKNETEKDALIREIREEMKCDLIVGDKVITTEHEYDFGIVRLTTYKCTLNKELPTLTEHKSIEWLSINELDKLNWAPADIPAVNKIMTEG

⊟Experimental data[edit | edit source]

  • experimentally validated: see SACOL2500
  • protein localization: see SACOL2500
  • quantitative data / protein copy number per cell: see SACOL2500
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Additional information (user-provided)[edit | edit source]

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Additional information (user-provided)[edit | edit source]

⊟Other information (user-provided)[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]


⊟Relevant publications[edit | edit source]

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