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NCBI: 03-AUG-2016

Summary[edit | edit source]

  • organism: Staphylococcus aureus NCTC8325
  • locus tag: SAOUHSC_02181
  • pan locus tag?: SAUPAN005046000
  • symbol: SAOUHSC_02181
  • pan gene symbol?:
  • synonym:
  • product: phi PVL orfs 18-19-like protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SAOUHSC_02181
  • symbol: SAOUHSC_02181
  • product: phi PVL orfs 18-19-like protein
  • replicon: chromosome
  • strand: -
  • coordinates: 2042547..2044037
  • length: 1491
  • essential: no DEG other strains

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    ATGCAAGATACAATTCAAATAGACAATAAAACAATTGGATGGCTGGTTGTGCAAAGAGGG
    TTCGAGATACCCTCTTTTAATTTTGTTACTGAAAAAGAAAACGTAAAAGGTAGAGCGGGA
    TCTATTGTTAAGAATCGTTATTTAAATGATATCGAATTTGATTTACCATTAATTATTCGA
    AACGAAAAATTGTCACCAGGTGGAGAAAAAACACACGATGATATATTAGAAGCATTGGTC
    AAGTTCTTCAATATTAAAGATTTAACACCTAAAAAACTTAAATTCAAATCTCAAAACTGG
    TATTGGTTTGCATATTTTGATGGTCCATTAAAATTACCGAAAAACCCAAGAGGTTCAGTG
    AAGTTCACTATAAAAGTAGTGTTAACAGATCCTTATAAATACTCGGTAACTGGAAACAAA
    AACACCGCGATTTCAGACCAAGTTTCAGTTGTAAATAGTGGGACTGCTGACACTCCTTTA
    ATTGTTGAAGCCCGAGCAATTAAACCATCTAGTTACTTTATGATCACTAAAAATGATGAA
    GATTATTTTATGGTTGGTGATGATGAGGTAACCAAAGAAGTTAAGGATTACATGCCTCCT
    GTTTATCATAGTGAGTTTCGTGATTTCAAAGGTTGGACTAAGATGATTACTGAAGATATT
    CCAAGTAATGATTTAGGTGGTAAGGTCGGCGGTGACTTTGTGATATCCAATCTTGGCGAA
    GGATATAAAGCAACTAATTTTCCTGATGCAAAAGGTTGGGTTGGTGCTGGCACGAAACGA
    GGGCTCCCTAAAGCGATGACAGATTTTCAAATTACCTATAAATGTATTGTTGAACAAAAA
    GGTAAAGGTGCCGGAAGAACAGCACAACATATTTATGATAGTGATGGTAAGTTACTTGCT
    TCTATTGGTTATGAAAATAAATATCATGATAGAAAAATAGGACATATTGTTGTTACGTTG
    TATAACCAAAAAGGAGACCCCAAAAAGATATACGACTATCAGAATAAACCGATAATGTAT
    AACTTGGACAGAATCGTTGTTTATATGCGGCTCAGAAGAGTAGGTAATAAATTTTCTATT
    AAAACTTGGAAATTTGATCACATTAAAGACCCAGATAGACGTAAACCTATTGATATGGAT
    GAGAAAGAGTGGATAGATGGCGGTAAGTTTTATCAGCGTCCAGCTTCTATCATAGCTATC
    TATAGTGCGAAGTATAACGGTTATAAGTGGATGGAGATGAATGGATTAGGTTCATTCAAT
    ACGGAGATTCTACCGAAACCGAAAGGCGCAAGGGATGTCATTATACAAAAAGGTGATTTA
    GTGAAAATAGATATGCAAGCAAAAAGTGTTGTCATCAATGAGGAACCAATGTTGAGCGAG
    AAATCGTTTGGAAGTAATTATTTCAATGTTGATTCTGGGTACAGTGAATTAATCATACAA
    CCTGAAAACGTCTTTGATACGACGGTTAAATGGCAAGATAGATATTTATAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1491

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SAOUHSC_02181
  • symbol: SAOUHSC_02181
  • description: phi PVL orfs 18-19-like protein
  • length: 496
  • theoretical pI: 9.45726
  • theoretical MW: 56828.6
  • GRAVY: -0.550202

Function[edit | edit source]

  • TIGRFAM:
  • TheSEED  :
    • Bacteriophage
  • PFAM:
    no clan defined Sipho_tail; Phage tail protein (PF05709; HMM-score: 178.8)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.003728
    • TAT(Tat/SPI): 0.000268
    • LIPO(Sec/SPII): 0.001099
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MQDTIQIDNKTIGWLVVQRGFEIPSFNFVTEKENVKGRAGSIVKNRYLNDIEFDLPLIIRNEKLSPGGEKTHDDILEALVKFFNIKDLTPKKLKFKSQNWYWFAYFDGPLKLPKNPRGSVKFTIKVVLTDPYKYSVTGNKNTAISDQVSVVNSGTADTPLIVEARAIKPSSYFMITKNDEDYFMVGDDEVTKEVKDYMPPVYHSEFRDFKGWTKMITEDIPSNDLGGKVGGDFVISNLGEGYKATNFPDAKGWVGAGTKRGLPKAMTDFQITYKCIVEQKGKGAGRTAQHIYDSDGKLLASIGYENKYHDRKIGHIVVTLYNQKGDPKKIYDYQNKPIMYNLDRIVVYMRLRRVGNKFSIKTWKFDHIKDPDRRKPIDMDEKEWIDGGKFYQRPASIIAIYSAKYNGYKWMEMNGLGSFNTEILPKPKGARDVIIQKGDLVKIDMQAKSVVINEEPMLSEKSFGSNYFNVDSGYSELIIQPENVFDTTVKWQDRYL

Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

  1. Ulrike Mäder, Pierre Nicolas, Maren Depke, Jan Pané-Farré, Michel Debarbouille, Magdalena M van der Kooi-Pol, Cyprien Guérin, Sandra Dérozier, Aurelia Hiron, Hanne Jarmer, Aurélie Leduc, Stephan Michalik, Ewoud Reilman, Marc Schaffer, Frank Schmidt, Philippe Bessières, Philippe Noirot, Michael Hecker, Tarek Msadek, Uwe Völker, Jan Maarten van Dijl
    Staphylococcus aureus Transcriptome Architecture: From Laboratory to Infection-Mimicking Conditions.
    PLoS Genet: 2016, 12(4);e1005962
    [PubMed:27035918] [WorldCat.org] [DOI] (I e)

Relevant publications[edit | edit source]