PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

⊟Summary

• pan ID^?: SAUPAN004556000
• symbol^?: hsdM2
• synonym:
• description^?: type I restriction-modification system subunit M

  descriptions from strain specific annotations:

  • type I restriction-modification system subunit M
  • type I restriction-modification system, M subunit
  • type I restriction-modification system, methylase subunit
  • type I restriction-modification system, methyltransferase subunit
  • type I restriction-modification system modification protein
  • type I restriction enzyme EcoR124II M protein
  • type I restriction enzyme modification protein
  • Type I restriction-modification system, DNA-methyltransferase subunit M
  • type I restriction-modification system DNA-methyltransferase
  • type I restriction-modification system M subunit
  • type I site-specific deoxyribonuclease methyltransferase subunit
• strand^?: -
• coordinates^?: 4780164..4788405
• synteny block^?: BlockID0035460
• occurrence^?: in 76% of 33 strains

⊟Orthologs

COL:
SACOL1862 (hsdM2)
N315:
SA1626
NCTC8325:
SAOUHSC_01933
Newman:
NWMN_1700 (hsdM)
USA300_FPR3757:
SAUSA300_1752 (hsdM)
04-02981:
SA2981_1763
08BA02176:
—
11819-97:
MS7_1808
6850:
RSAU_001665 (hsdM)
71193:
—
ECT-R 2:
ECTR2_1641 (hsdM)
ED133:
SAOV_1794
ED98:
SAAV_1816 (hsdM)
HO 5096 0412:
—
JH1:
SaurJH1_1895
JH9:
SaurJH9_1860
JKD6008:
—
JKD6159:
—
LGA251:
SARLGA251_16900
M013:
—
MRSA252:
SAR1899
MSHR1132:
—
MSSA476:
SAS1732
Mu3:
SAHV_1793
Mu50:
SAV1808
MW2:
MW1751 (hsdM)
RF122:
SAB1668c (hsdM)
ST398:
—
T0131:
SAT0131_01928
TCH60:
HMPREF0772_11335
TW20:
SATW20_18050
USA300_TCH1516:
USA300HOU_1800 (hsdM2)
VC40:
SAVC_08275

⊟Genome Viewer

COL
N315
NCTC8325
Newman
USA300_FPR3757

⊟Alignments

• alignment of orthologues:
  CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
  
  
  COL             ------------------------------------------------------------
  N315            ------------------------------------------------------------
  NCTC8325        MILKAFESYNISIKFFNNNCATKTQNFHHQHPNYQHRNITKCYNKSITQRDKLLMQRRRN
  Newman          MILKAFESYNISIKFFNNNCATKTQNFHHQHPNYQHRNITKCYNKSITQRDKLLMQRRRN
  USA300_FPR3757  MILKAFESYNISIKFFNNNCATKTQNFHHQHPNYQHRNITKCYNKSITQRDKLLMQRRRN
                                                                              
  
  COL             -MSITEKQRQQQAELHKKLWSIANDLRGNMDASEFRNYILGLIFYRFLSEKAEQEYADAL
  N315            -MSITEKQRQQQAELHKKLWSIANDLRGNMDASEFRNYILGLIFYRFLSEKAEQEYADAL
  NCTC8325        HMSITEKQRQQQAELHKKLWSIANDLRGNMDASEFRNYILGLIFYRFLSEKAEQEYADAL
  Newman          HMSITEKQRQQQAELHKKLWSIANDLRGNMDASEFRNYILGLIFYRFLSEKAEQEYADAL
  USA300_FPR3757  HMSITEKQRQQQAELHKKLWSIANDLRGNMDASEFRNYILGLIFYRFLSEKAEQEYADAL
                   ***********************************************************
  
  COL             SGEDITYQEAWADEEYREDLKAELIDQVGYFIEPQDLFSAMIREIETQDFDIEHLATAIR
  N315            SGEDITYQEAWADEEYREDLKAELIDQVGYFIEPQDLFSAMIREIETQDFDIEHLATAIR
  NCTC8325        SGEDITYQEAWADEEYREDLKAELIDQVGYFIEPQDLFSAMIREIETQDFDIEHLATAIR
  Newman          SGEDITYQEAWADEEYREDLKAELIDQVGYFIEPQDLFSAMIREIETQDFDIEHLATAIR
  USA300_FPR3757  SGEDITYQEAWADEEYREDLKAELIDQVGYFIEPQDLFSAMIREIETQDFDIEHLATAIR
                  ************************************************************
  
  COL             KVETSTLGEESENDFIGLFSDMDLSSTRLGNNVKERTALISKVMVNLDDLPFVHSDMEID
  N315            KVETSTLGEESENDFIGLFSDMDLSSTRLGNNVKERTALISKVMVNLDDLPFVHSDMEID
  NCTC8325        KVETSTLGEESENDFIGLFSDMDLSSTRLGNNVKERTALISKVMVNLDDLPFVHSDMEID
  Newman          KVETSTLGEESENDFIGLFSDMDLSSTRLGNNVKERTALISKVMVNLDDLPFVHSDMEID
  USA300_FPR3757  KVETSTLGEESENDFIGLFSDMDLSSTRLGNNVKERTALISKVMVNLDDLPFVHSDMEID
                  ************************************************************
  
  COL             MLGDAYEFLIGRFAATAGKKAGEFYTPQQVSKILAKIVTDGKDKLRHVYDPTCGSGSLLL
  N315            MLGDAYEFLIGRFAATAGKKAGEFYTPQQVSKILAKIVTDGKDKLRHVYDPTCGSGSLLL
  NCTC8325        MLGDAYEFLIGRFAATAGKKAGEFYTPQQVSKILAKIVTDGKDKLRHVYDPTCGSGSLLL
  Newman          MLGDAYEFLIGRFAATAGKKAGEFYTPQQVSKILAKIVTDGKDKLRHVYDPTCGSGSLLL
  USA300_FPR3757  MLGDAYEFLIGRFAATAGKKAGEFYTPQQVSKILAKIVTDGKDKLRHVYDPTCGSGSLLL
                  ************************************************************
  
  COL             RVGKETQVYRYFGQERNNTTYNLARMNMLLHDVRYENFDIRNDDTLENPAFLGNTFDAVI
  N315            RVGKETQVYRYFGQERNNTTYNLARMNMLLHDVRYENFEIRNDDTLENPAFLGNTFDAVI
  NCTC8325        RVGKETQVYRYFGQERNNTTYNLARMNMLLHDVRYENFEIRNDDTLENPAFLGNTFDAVI
  Newman          RVGKETQVYRYFGQERNNTTYNLARMNMLLHDVRYENFDIRNDDTLENPAFLGNTFDAVI
  USA300_FPR3757  RVGKETQVYRYFGQERNNTTYNLARMNMLLHDVRYENFDIRNDDTLENPAFLGNTFDAVI
                  **************************************:*********************
  
  COL             ANPPYSAKWTADSKFENDERFSGYGKLAPKSKADFAFIQHMVHYLDDEGTMAVVLPHGVL
  N315            ANPPYSAKWTADSKFENDERFSGYGKLAPKSKADFAFIQHMVHYLDDEGTMAVVLPHGVL
  NCTC8325        ANPPYSAKWTADSKFENDERFSGYGKLAPKSKADFAFIQHMVHYLDDEGTMAVVLPHGVL
  Newman          ANPPYSAKWTADSKFENDERFSGYGKLAPKSKADFAFIQHMVHYLDDEGTMAVVLPHGVL
  USA300_FPR3757  ANPPYSAKWTADSKFENDERFSGYGKLAPKSKADFAFIQHMVHYLDDEGTMAVVLPHGVL
                  ************************************************************
  
  COL             FRGAAEGVIRRYLIEEKNYLEAVIGLPANIFYGTSIPTCILVFKKCRQQDDNVLFIDASN
  N315            FRGAAEGVIRRYLIEEKNYLEAVIGLPANIFYGTSIPTCILVFKKCRQQDDNVLFIDASN
  NCTC8325        FRGAAEGVIRRYLIEEKNYLEAVIGLPANIFYGTSIPTCILVFKKCRQQDDNVLFIDASN
  Newman          FRGAAEGVIRRYLIEEKNYLEAVIGLPANIFYGTSIPTCILVFKKCRQQDDNVLFIDASN
  USA300_FPR3757  FRGAAEGVIRRYLIEEKNYLEAVIGLPANIFYGTSIPTCILVFKKCRQQDDNVLFIDASN
                  ************************************************************
  
  COL             DFEKGKNQNHLSDAQVERIIDTYKRKETIDKYSYSATLQEIADNDYNLNIPRYVDTFEEE
  N315            DFEKGKNQNHLSDAQVERIIDTYKRKATIDKYSYSATLQEIADNDYNLNIPRYVDTFEEE
  NCTC8325        DFEKGKNQNHLSDAQVERIIDTYKRKATIDKYSYSATLQEIADNDYNLNIPRYVDTFEEE
  Newman          DFEKGKNQNHLSDAQVERIIDTYKRKETIDKYSYSATLQEIADNDYNLNIPRYVDTFEEE
  USA300_FPR3757  DFEKGKNQNHLSDAQVERIIDTYKRKETIDKYSYSATLQEIADNDYNLNIPRYVDTFEEE
                  ************************** *********************************
  
  COL             APIDLDQVQQDLKNIDKEIAEIEQEINAYLKELGVLKDE
  N315            APIDLDQVQQDLKNIDKEIAEIEQEINAYLKELGVLKDE
  NCTC8325        APIDLDQVQQDLKNIDKEIAEIEQEINAYLKELGVLKDE
  Newman          APIDLDQVQQDLKNIDKEIAEIEQEINAYLKELGVLKDE
  USA300_FPR3757  APIDLDQVQQDLKNIDKEIAEIEQEINAYLKELGVLKDE
                  ***************************************