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Summary[edit | edit source]

  • pan ID?: SAUPAN004833000
  • symbol?: rrl3
  • synonym:
  • description?: 23S ribosomal RNA
  • strand?: -
  • coordinates?: 5015128..5018051
  • synteny block?: BlockID0037630
  • occurrence?: in 97% of 33 strains

rrlC : 23S ribosomal RNA [1]

• A crystal structure is available : 6YEF

Staphylococcal 23S rRNA is modified by methylation at uridine(792) and at uridine(1966) by rlmCD, methylation and inversion at pseudouridine(1942) by rlmH and rluD, methylation at guanosine(2278) by rlmB, methylation at guanosine(2472) by rlmK, uridine reduction at dihydrouridine(2476), methylation at adenosine(2530) by rlmN, and methylation at guanosine(2601) by rlmQ.

Orthologs[edit | edit source]

    COL:
    SACOL_Sa23SD (rrlD)
    N315:
    NCTC8325:
    Newman:
    USA300_FPR3757:
    04-02981:
    SA2981_rRNA09
    08BA02176:
    C248_1930
    11819-97:
    MS7_1892
    6850:
    RSAU_001745
    71193:
    ST398NM01_r061
    ECT-R 2:
    ECTR2_1730
    ED133:
    SAOV_1884c
    ED98:
    SAAV_1907a
    HO 5096 0412:
    SAEMRSA15_rRNA0012
    JH1:
    SaurJH1_R0064
    JH9:
    SaurJH9_R0064
    JKD6008:
    SAA6008_r09
    JKD6159:
    SAA6159_r09
    LGA251:
    SARLGA251_r10
    M013:
    M013TW_1891
    MRSA252:
    SARr009
    MSHR1132:
    SAMSHR1132_r08
    MSSA476:
    SASr012
    Mu3:
    SAHV_r0009
    Mu50:
    SAVrRNA09
    MW2:
    MWrRNA12
    RF122:
    SAB_r09
    ST398:
    T0131:
    SAT0131_r011
    TCH60:
    HMPREF0772_r10015
    TW20:
    SATW20_r090
    USA300_TCH1516:
    USA300HOU_r0009 (rrl3)
    VC40:
    SAVC_r12615

Genome Viewer[edit | edit source]

COL
N315
NCTC8325
Newman
USA300_FPR3757

Alignments[edit | edit source]

  • alignment of orthologues:

  1. Alexander Golubev, Bulat Fatkhullin, Iskander Khusainov, Lasse Jenner, Azat Gabdulkhakov, Shamil Validov, Gulnara Yusupova, Marat Yusupov, Konstantin Usachev
    Cryo-EM structure of the ribosome functional complex of the human pathogen Staphylococcus aureus at 3.2 Å resolution.
    FEBS Lett: 2020, 594(21);3551-3567
    [PubMed:32852796] [WorldCat.org] [DOI] (I p)
    Adrián González-López, Daniel S D Larsson, Ravi Kiran Koripella, Brett N Cain, Martin Garcia Chavez, Paul J Hergenrother, Suparna Sanyal, Maria Selmer
    Structures of the Staphylococcus aureus ribosome inhibited by fusidic acid and fusidic acid cyclopentane.
    Sci Rep: 2024, 14(1);14253
    [PubMed:38902339] [WorldCat.org] [DOI] (I e)
    Roberto Bahena-Ceron, Chloé Teixeira, Jose R Jaramillo Ponce, Philippe Wolff, Florence Couzon, Pauline François, Bruno P Klaholz, François Vandenesch, Pascale Romby, Karen Moreau, Stefano Marzi
    RlmQ: a newly discovered rRNA modification enzyme bridging RNA modification and virulence traits in Staphylococcus aureus.
    RNA: 2024, 30(3);200-212
    [PubMed:38164596] [WorldCat.org] [DOI] (I e)