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⊟Summary[edit | edit source]
- pan ID?: SAUPAN005318000
- symbol?: rrlE
- synonym:
- description?: 23S ribosomal RNA
- strand?: -
- coordinates?: 5479210..5493256
- synteny block?: BlockID0041170
- occurrence?: in 94% of 34 strains
rrlE : 23S ribosomal RNA [1]
• A crystal structure is available : 6YEF
Staphylococcal 23S rRNA is modified by methylation at uridine(792) and at uridine(1966) by rlmCD, methylation and inversion at pseudouridine(1942) by rlmH and rluD, methylation at guanosine(2278) by rlmB, methylation at guanosine(2472) by rlmK, uridine reduction at dihydrouridine(2476), methylation at adenosine(2530) by rlmN, and methylation at guanosine(2601) by rlmQ.
⊟Orthologs[edit | edit source]
04-02981:
SA2981_rRNA12
08BA02176:
C248_2069
11819-97:
MS7_2075
6850:
RSAU_001898
71193:
ST398NM01_r060
ECT-R 2:
ECTR2_1914
ED133:
SAOV_2100c
ED98:
SAAV_2110a
HO 5096 0412:
SAEMRSA15_rRNA0015
JH1:
SaurJH1_R0069
JH9:
SaurJH9_R0069
JKD6008:
SAA6008_r12
JKD6159:
SAA6159_r12
JSNZ:
JSNZ_002019
LGA251:
—
M013:
M013TW_2017
MRSA252:
SARr012
MSHR1132:
SAMSHR1132_r11
MSSA476:
SASr015
Mu3:
SAHV_r0012
Mu50:
SAVrRNA12
MW2:
MWrRNA15
RF122:
SAB_r12
ST398:
—
T0131:
SAT0131_r014
TCH60:
HMPREF0772_r10012
TW20:
SATW20_r120
USA300_TCH1516:
USA300HOU_r0012 (rrl4)
VC40:
SAVC_r12617
⊟Genome Viewer[edit | edit source]
| COL | |
| N315 | |
| NCTC8325 | |
| Newman | |
| USA300_FPR3757 |
⊟Alignments[edit | edit source]
- alignment of orthologues:
- ↑ Alexander Golubev, Bulat Fatkhullin, Iskander Khusainov, Lasse Jenner, Azat Gabdulkhakov, Shamil Validov, Gulnara Yusupova, Marat Yusupov, Konstantin Usachev
Cryo-EM structure of the ribosome functional complex of the human pathogen Staphylococcus aureus at 3.2 Å resolution.
FEBS Lett: 2020, 594(21);3551-3567
[PubMed:32852796] [WorldCat.org] [DOI] (I p)Adrián González-López, Daniel S D Larsson, Ravi Kiran Koripella, Brett N Cain, Martin Garcia Chavez, Paul J Hergenrother, Suparna Sanyal, Maria Selmer
Structures of the Staphylococcus aureus ribosome inhibited by fusidic acid and fusidic acid cyclopentane.
Sci Rep: 2024, 14(1);14253
[PubMed:38902339] [WorldCat.org] [DOI] (I e)Roberto Bahena-Ceron, Chloé Teixeira, Jose R Jaramillo Ponce, Philippe Wolff, Florence Couzon, Pauline François, Bruno P Klaholz, François Vandenesch, Pascale Romby, Karen Moreau, Stefano Marzi
RlmQ: a newly discovered rRNA modification enzyme bridging RNA modification and virulence traits in Staphylococcus aureus.
RNA: 2024, 30(3);200-212
[PubMed:38164596] [WorldCat.org] [DOI] (I e)