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⊟Summary[edit | edit source]
- pan ID?: SAUPAN005527000
- symbol?: rrlF
- synonym:
- description?: 23S ribosomal RNA
- strand?: -
- coordinates?: 5679108..5687152
- synteny block?: BlockID0043060
- occurrence?: in 97% of 34 strains
rrlF : 23S ribosomal RNA [1]
• A crystal structure is available : 6YEF
Staphylococcal 23S rRNA is modified by methylation at uridine(792) and at uridine(1966) by rlmCD, methylation and inversion at pseudouridine(1942) by rlmH and rluD, methylation at guanosine(2278) by rlmB, methylation at guanosine(2472) by rlmK, uridine reduction at dihydrouridine(2476), methylation at adenosine(2530) by rlmN, and methylation at guanosine(2601) by rlmQ.
⊟Orthologs[edit | edit source]
04-02981:
SA2981_rRNA15
08BA02176:
C248_2200
11819-97:
MS7_2187
6850:
RSAU_002008
71193:
ST398NM01_r062
ECT-R 2:
ECTR2_2025
ED133:
SAOV_2211c
ED98:
SAAV_2225a
HO 5096 0412:
SAEMRSA15_rRNA0018
JH1:
SaurJH1_R0080
JH9:
SaurJH9_R0080
JKD6008:
SAA6008_r15
JKD6159:
SAA6159_r15
JSNZ:
JSNZ_002132
LGA251:
SARLGA251_r13
M013:
M013TW_2130
MRSA252:
SARr015
MSHR1132:
SAMSHR1132_r14
MSSA476:
SASr018
Mu3:
SAHV_r0015
Mu50:
SAVrRNA15
MW2:
MWrRNA18
RF122:
SAB_r15
ST398:
—
T0131:
SAT0131_r017
TCH60:
HMPREF0772_r10009
TW20:
SATW20_r150
USA300_TCH1516:
USA300HOU_r0015 (rrl5)
VC40:
SAVC_r12619
⊟Genome Viewer[edit | edit source]
COL | |
N315 | |
NCTC8325 | |
Newman | |
USA300_FPR3757 |
⊟Alignments[edit | edit source]
- alignment of orthologues:
- ↑ Alexander Golubev, Bulat Fatkhullin, Iskander Khusainov, Lasse Jenner, Azat Gabdulkhakov, Shamil Validov, Gulnara Yusupova, Marat Yusupov, Konstantin Usachev
Cryo-EM structure of the ribosome functional complex of the human pathogen Staphylococcus aureus at 3.2 Å resolution.
FEBS Lett: 2020, 594(21);3551-3567
[PubMed:32852796] [WorldCat.org] [DOI] (I p)Adrián González-López, Daniel S D Larsson, Ravi Kiran Koripella, Brett N Cain, Martin Garcia Chavez, Paul J Hergenrother, Suparna Sanyal, Maria Selmer
Structures of the Staphylococcus aureus ribosome inhibited by fusidic acid and fusidic acid cyclopentane.
Sci Rep: 2024, 14(1);14253
[PubMed:38902339] [WorldCat.org] [DOI] (I e)Roberto Bahena-Ceron, Chloé Teixeira, Jose R Jaramillo Ponce, Philippe Wolff, Florence Couzon, Pauline François, Bruno P Klaholz, François Vandenesch, Pascale Romby, Karen Moreau, Stefano Marzi
RlmQ: a newly discovered rRNA modification enzyme bridging RNA modification and virulence traits in Staphylococcus aureus.
RNA: 2024, 30(3);200-212
[PubMed:38164596] [WorldCat.org] [DOI] (I e)