PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 10-JUN-2013

⊟Summary

• organism: Staphylococcus aureus USA300_FPR3757
• locus tag: SAUSA300_0075 [new locus tag: SAUSA300_RS00380 ]
• pan locus tag^?: SAUPAN000823000
• symbol: opp-3C
• pan gene symbol^?: opp-3C
• synonym:
• product: oligopeptide permease, channel-forming protein

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SAUSA300_0075 [new locus tag: SAUSA300_RS00380 ]
• symbol: opp-3C
• product: oligopeptide permease, channel-forming protein
• replicon: chromosome
• strand: +
• coordinates: 82906..83673
• length: 768
• essential: unknown

⊟Accession numbers

• Gene ID: 3912840 NCBI
• RefSeq: YP_492793 NCBI
• BioCyc: see SAUSA300_RS00380
• MicrobesOnline: 1291590 MicrobesOnline

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

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  ATGAAAAAATATCAAACGTACATCGCAATAGGTTCACTATTGAGTTTGATGGTTGTATTA
  ATTACGTATGGTTTAATGCAAGACACGCAACATTTGAACCCACTTGAGTCACCTAATGGA
  CAACATTGGTTGGGTACCGATCAATTAGGCAGAGACTTCTTAGTAAGACTGATTGTCGGT
  AGTCTTGTCACATTGAGTTTAACAGGCATAGTGATTCTATTAAGCGTTTGTATGGGACTT
  ATCTTTGGCTTAATTGCAGGCATAGAAAGACGATGGTTAGATCAAATCATCATGTTTGTT
  GCCGATATGTTGCTGGCTATTCCGTCATTTATTATCGCATTAGTCATCTTAAGTTTAGTA
  AGTAACTCCATGATAGGTTTGATACTTGCTTTAACGATTGGATGGATAGGACGTTATTTA
  CGTTACTTCAGAAATTTAACGCGAGATATTCAAAAACGTCCATTTGTTCAATATGCACGA
  TTGAGTGGGAACTCAACATTCAAAACGACAGTAACACATGTGATTCCACATTTATTAAGT
  AGTATATTCGCTTTGGTAACGGCTGACTTTGGCAAAATGATGCTCAGCATATCTGGACTT
  GCTTTTCTAGGACTAGGTATTAAACCGCCGACGCCTGAGTTAGGAACAATTCTTTTTGAT
  GGGAAAAGTTATTTCAACGGCGCACCGTGGCTCTTCTTCTTCCCTGGTGTATTGTTAGGA
  GGTTTCGCCTTATTATGTCAAATTATCAACAAAAAAATAACGCAGTAA
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⊟Protein

⊟General

• locus tag: SAUSA300_0075 [new locus tag: SAUSA300_RS00380 ]
• symbol: Opp-3C
• description: oligopeptide permease, channel-forming protein
• length: 255
• theoretical pI: 10.1061
• theoretical MW: 28224.7
• GRAVY: 0.747843

⊟Function

• TIGRFAM:
  Metabolism Transport and binding proteins Cations and iron carrying compounds nickel ABC transporter, permease subunit NikC (TIGR02790; EC 3.6.3.24; HMM-score: 180.3)
  and 5 more
  Metabolism Transport and binding proteins Anions phosphonate ABC transporter, permease protein PhnE (TIGR01097; HMM-score: 35.1)
  Metabolism Transport and binding proteins Cations and iron carrying compounds nickel ABC transporter, permease subunit NikB (TIGR02789; EC 3.6.3.24; HMM-score: 29.4)
  Metabolism Transport and binding proteins Anions phosphate ABC transporter, permease protein PstA (TIGR00974; HMM-score: 15.5)
  Metabolism Transport and binding proteins Amino acids, peptides and amines amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family (TIGR01726; HMM-score: 9.3)
  ectoine/hydroxyectoine ABC transporter, permease protein EhuD (TIGR03003; HMM-score: 8.3)
• TheSEED  :
  • Nickel transport system permease protein NikC (TC 3.A.1.5.3)
  Membrane Transport Membrane Transport - no subcategory Transport of Nickel and Cobalt  Nickel transport system permease protein NikC (TC 3.A.1.5.3)
• PFAM:
  BPD_transp_1 (CL0404) BPD_transp_1; Binding-protein-dependent transport system inner membrane component (PF00528; HMM-score: 74.8)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic Membrane
  • Cytoplasmic Score: 0
  • Cytoplasmic Membrane Score: 10
  • Cellwall Score: 0
  • Extracellular Score: 0
  • Internal Helices: 6
• LocateP: Multi-transmembrane
  • Prediction by SwissProt Classification: Membrane
  • Pathway Prediction: Sec-(SPI)
  • Intracellular possibility: 0.17
  • Signal peptide possibility: -1
  • N-terminally Anchored Score: 1
  • Predicted Cleavage Site: No CleavageSite
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.188062
  • TAT(Tat/SPI): 0.000408
  • LIPO(Sec/SPII): 0.049847
• predicted transmembrane helices (TMHMM): 6

⊟Accession numbers

• GI: 87160395 NCBI
• RefSeq: YP_492793 NCBI
• UniProt: A0A0H2XGJ4 UniProt

⊟Protein sequence

• MKKYQTYIAIGSLLSLMVVLITYGLMQDTQHLNPLESPNGQHWLGTDQLGRDFLVRLIVGSLVTLSLTGIVILLSVCMGLIFGLIAGIERRWLDQIIMFVADMLLAIPSFIIALVILSLVSNSMIGLILALTIGWIGRYLRYFRNLTRDIQKRPFVQYARLSGNSTFKTTVTHVIPHLLSSIFALVTADFGKMMLSISGLAFLGLGIKPPTPELGTILFDGKSYFNGAPWLFFFPGVLLGGFALLCQIINKKITQ

⊟Experimental data

• experimentally validated:
• protein localization:
• quantitative data / protein copy number per cell:
• interaction partners:

⊟Expression & Regulation

⊟Operon

• MicrobesOnline: SAUSA300_0072 > SAUSA300_0073 > opp-3B > opp-3C > SAUSA300_0076 > SAUSA300_0077

⊟Regulation

• regulator:

⊟Transcription pattern

• S.aureus Expression Data Browser: no data available

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications