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NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus USA300_FPR3757
  • locus tag: SAUSA300_RS04605 [old locus tag: SAUSA300_0853 ]
  • pan locus tag?: SAUPAN003051000
  • symbol: SAUSA300_RS04605
  • pan gene symbol?: mnhC1
  • synonym:
  • product: Na(+)/H(+) antiporter subunit C

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SAUSA300_RS04605 [old locus tag: SAUSA300_0853 ]
  • symbol: SAUSA300_RS04605
  • product: Na(+)/H(+) antiporter subunit C
  • replicon: chromosome
  • strand: -
  • coordinates: 930927..931256
  • length: 330
  • essential: unknown other strains

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    ATGATTTTTGTTAGTGGTATTCTCACAGCAATTAGTGTCTATCTCGTTTTGTCTAAAAGT
    CTGATACGAATTGTTATGGGAACTACACTATTAACACATGCAGCAAATTTATTTTTAATA
    ACTATGGGCGGACTTAAACATGGTACTGTTCCAATTTATGAAGCGAACGTAAAAAGCTAT
    GTTGATCCTATCCCGCAAGCACTTATTTTAACAGCAATCGTTATCGCCTTTGCGACAACA
    GCCTTTTTCTTAGTATTAGCATTTAGAACATATAAAGAATTAGGCACAGATAACGTTGAG
    AGTATGAAAGGAGTTCCAGAAGATGATTGA
    60
    120
    180
    240
    300
    330

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SAUSA300_RS04605 [old locus tag: SAUSA300_0853 ]
  • symbol: SAUSA300_RS04605
  • description: Na(+)/H(+) antiporter subunit C
  • length: 109
  • theoretical pI: 6.51458
  • theoretical MW: 11805.9
  • GRAVY: 0.802752

Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Cations and iron carrying compounds multicomponent Na+:H+ antiporter, MnhC subunit (TIGR00941; HMM-score: 168.4)
  • TheSEED: see SAUSA300_0853
  • PFAM:
    no clan defined Oxidored_q2; NADH-ubiquinone/plastoquinone oxidoreductase chain 4L (PF00420; HMM-score: 110.7)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 3
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.145951
    • TAT(Tat/SPI): 0.004358
    • LIPO(Sec/SPII): 0.005605
  • predicted transmembrane helices (TMHMM): 2

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MIFVSGILTAISVYLVLSKSLIRIVMGTTLLTHAANLFLITMGGLKHGTVPIYEANVKSYVDPIPQALILTAIVIAFATTAFFLVLAFRTYKELGTDNVESMKGVPEDD

Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]