PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 02-MAR-2017

⊟Summary

• organism: Staphylococcus aureus N315
• locus tag: SA_RS00440 [old locus tag: SA0059 ]
• pan locus tag^?: SAUPAN000446000
• symbol: SA_RS00440
• pan gene symbol^?: —
• synonym:
• product: hypothetical protein

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SA_RS00440 [old locus tag: SA0059 ]
• symbol: SA_RS00440
• product: hypothetical protein
• replicon: chromosome
• strand: -
• coordinates: 66630..68423
• length: 1794
• essential: no DEG

⊟Accession numbers

• Location: NC_002745 (66630..68423) NCBI
• BioCyc: SA_RS00440 BioCyc
• MicrobesOnline: see SA0059

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
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  121
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  481
  541
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  661
  721
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  841
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  1021
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  1141
  1201
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  1321
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  1441
  1501
  1561
  1621
  1681
  1741
  
  ATGACTCAAACTAACCCTTCATTTAATCCTTCACCACGATACAAATCAAAAAAAGGTTGG
  TATAAAGACAAGCCTCCCAAAGAAAAAGGAGGAATGCCTACTGAAGTTGAAATCGCAGGT
  CCTATCGTTATCGAAAATAAGTTTATTGACCCTAAAACTAACACTGAAAAAGTAATTATT
  ACAGACGAGGATCAAAAAGAAATTGTTGAATCTAGTGATATTTTAACAACACAAAAACTG
  CCATCTTTAATGAAGTATGGATTTAGTATTAATGAAAAATATACAAAAGATTTAGGTTAT
  GCGTTGCAACAAATGCGCAATCAATTACCCATTTCCTACTTATATGAAGGGGTAGGTATA
  CTGGAAACACCGTTTGGTCCTATTGTATCGTTAAGTGAAATCTATACTACTAAAGAATTT
  GATAATAAATCTCCATCTGACGCCATTTGTGATAATGCTTATGACTTAACTCCTAAAGGT
  ACATTTGATAATTGGTTTAACATGTATCTAAAAGAGGTTAAAGGTTCTCTTCTTTTAGAA
  TTAGCAGTCGTATTTGGTATTTCTGCCTTAGTGACGAGTTTCCTGAAGCACAAACATGAA
  ACCGAATTTGCCGGAATCATTTTTAGTTTTACAGGTCAATCCTCAACCGGTAAGTCAACT
  GCAGCTTCTTTAGCTGTATCAGTCGCTGGTAACCCTACCAAAGGTAATGAAACTCTCTTT
  AGAAATTGGAATGCCACACGTAATGCACTTGAAGGTTACTTGAGTAACAATTTTGGTATA
  CCTATTGTATTTGATGAACTCTCATCAGCAACTTTTAGAGATACAACGGGGTTATTGTAC
  TCCATCACTGAAGGTCAAGGTCGTCAACGTTCAAACGTTCATGGAGAAGTTAAAACGCCT
  AAGAATTGGGGTACTTCTGTCATTTCAACGTCAGAACACAGTATTTTTAATGATTCAGCT
  CAAAACGATGGATTACGTGTAAGAACCATCGAGATTAATGAACAATTCACTACAAATGCG
  ACCAATGCTGACAATATTAAAAAAGCTGTAGCACTAAACTATGGTCATGTTTTACCGTTA
  GTAGCTAAATATCTTATAAATCGTGAAGATGAAGTTATTCAATGGTTTTACAAGGAAGTA
  GATTGGTTTGAAGCTAAATTGAAAGATGATAAAAGCAACACAGGCAATCGTATGTTTAAG
  CGTTATGCAGTCATTACAACATCTGCAAAAATATTAGGTCGTGTTTTAGCTACAGATATT
  GATATCGCTAAAATAAGAGACTACTTTATTGATTATCATGGTCATACAATCTCTGAACGC
  TCATTAGCTGATAAAGCTATCGATGTCATCATTCAATTTGTAGCACAAAACAGAGGTAAG
  TTTTCAGATGAAGGTGCTTTGAAAAATATGTTTGAGAACTATGGATTAATCTCATTAAAA
  GATGACCATATCGAAGTAAAAATGATTGCAAACGTTTTTAAACAGATGCTAAACAATCAT
  CAATTTCAAGATGTTAATAATGTTGTCAACGCCTTAAGAGATAAAGGTTTCATATTAGCT
  GACCGTGGACGCCAAACAACTAAAAGAAGTGTCAAAGATAATAGCGGTAAAAAACAATCA
  CTTGTATTTTACCATCTAAAATTAGATGTAGAGTTTGCATCTATCCTGGGATTAACTAAA
  GATAAGTCGTTAATTCAAAATTGGACACCGGCAAATGATAACAAAGCTGCGAAAGAACTT
  TTTAAATCCGCTAATGAGGGGATAGGCCCTTCAGGAGTTCACGAAGATTTCTGA
  60
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  1140
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  1260
  1320
  1380
  1440
  1500
  1560
  1620
  1680
  1740
  1794
  

⊟Protein

⊟General

• locus tag: SA_RS00440 [old locus tag: SA0059 ]
• symbol: SA_RS00440
• description: hypothetical protein
• length: 597
• theoretical pI: 7.42234
• theoretical MW: 67037.3
• GRAVY: -0.436013

⊟Function

• TIGRFAM:
• TheSEED: see SA0059
• PFAM:
  P-loop_NTPase (CL0023) DUF927; Domain of unknown function (DUF927) (PF06048; HMM-score: 255.2)
  and 2 more
  AAA_29; P-loop containing region of AAA domain (PF13555; HMM-score: 12.7)
  Thioredoxin (CL0172) GSHPx; Glutathione peroxidase (PF00255; HMM-score: 12.1)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: unknown (no significant prediction)
  • Cytoplasmic Score: 2.5
  • Cytoplasmic Membrane Score: 2.5
  • Cellwall Score: 2.5
  • Extracellular Score: 2.5
  • Internal Helix: 1
• LocateP:
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.008101
  • TAT(Tat/SPI): 0.00052
  • LIPO(Sec/SPII): 0.002309
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI: 446117245 NCBI
• RefSeq: WP_000195100 NCBI
• UniProt: see SA0059

⊟Protein sequence

• MTQTNPSFNPSPRYKSKKGWYKDKPPKEKGGMPTEVEIAGPIVIENKFIDPKTNTEKVIITDEDQKEIVESSDILTTQKLPSLMKYGFSINEKYTKDLGYALQQMRNQLPISYLYEGVGILETPFGPIVSLSEIYTTKEFDNKSPSDAICDNAYDLTPKGTFDNWFNMYLKEVKGSLLLELAVVFGISALVTSFLKHKHETEFAGIIFSFTGQSSTGKSTAASLAVSVAGNPTKGNETLFRNWNATRNALEGYLSNNFGIPIVFDELSSATFRDTTGLLYSITEGQGRQRSNVHGEVKTPKNWGTSVISTSEHSIFNDSAQNDGLRVRTIEINEQFTTNATNADNIKKAVALNYGHVLPLVAKYLINREDEVIQWFYKEVDWFEAKLKDDKSNTGNRMFKRYAVITTSAKILGRVLATDIDIAKIRDYFIDYHGHTISERSLADKAIDVIIQFVAQNRGKFSDEGALKNMFENYGLISLKDDHIEVKMIANVFKQMLNNHQFQDVNNVVNALRDKGFILADRGRQTTKRSVKDNSGKKQSLVFYHLKLDVEFASILGLTKDKSLIQNWTPANDNKAAKELFKSANEGIGPSGVHEDF

⊟Experimental data

• experimentally validated:
• protein localization:
• quantitative data / protein copy number per cell:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator:

⊟Transcription pattern

• S.aureus Expression Data Browser: no data available

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications