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NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS04940 [old locus tag: SA0874 ]
  • pan locus tag?: SAUPAN003193000
  • symbol: SA_RS04940
  • pan gene symbol?: ltaA
  • synonym:
  • product: MFS transporter

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SA_RS04940 [old locus tag: SA0874 ]
  • symbol: SA_RS04940
  • product: MFS transporter
  • replicon: chromosome
  • strand: -
  • coordinates: 989715..990923
  • length: 1209
  • essential: no DEG other strains

Accession numbers[edit | edit source]

  • Location: NC_002745 (989715..990923) NCBI
  • BioCyc: SA_RS04940 BioCyc
  • MicrobesOnline: see SA0874

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    ATGGAAAGGTTCCTTTATATGCAAGATTCTTCGTTAAATAATTACGCTAATCATAAAAAT
    TTCATTTTAATGCTTATTATCTTATTTTTAATGGAATTTGCGAGAGGCATGTATATCCTA
    AGCTATATTAATTTCTTGCCAACAGTTACATCCATTGCTGTAGCAATAACGTCTCTAGCA
    TTTTCAATACATTTTATTGCTGATGCATCTACAAACTTTGTTATAGGATTTTTACTGAAA
    AAATTCGGCACAAAAATCGTTTTAACGACTGGATTTATTTTAGCATTTACAAGTTTATTT
    TTAGTTATTTGGTTTCCAGCATCACCTTTTGTAATCATATTTAGTGCTATGATGCTCGGT
    ATTGCAGTTAGTCCTATTTGGGTCATTATGTTATCCAGTGTTGAAGAAGATAAACGTGGC
    AAACAAATGGGCTATGTTTATTTTTCATGGTTGTTAGGCCTATTGGTAGGTATGGTTTTT
    ATGAATCTACTTATCAAAGTGCACCCAACACGCTTTGCCTTCATGATGTCTTTAGTCGTT
    TTAATTGCATGGATATTATATTATTTTGTCGATGTAAAGTTAACAAATTATAATACTCGT
    CCAGTTAAAGCTCAATTGAGACAAATTGTTGATGTGACAAAGCGCCATTTATTGTTGTTC
    CCTGGTATTCTTTTACAAGGTGCCGCAATTGCTGCCCTAGTTCCTATATTACCAACATAT
    GCTACTAAGGTTATTAACGTAAGCACAATTGAATATACTGTTGCAATCATTATTGGTGGT
    ATCGGCTGTGCAGTTTCGATGCTATTTTTATCGAAACTAATAGATAACCGCAGCAGAAAC
    TTTATGTATGGTGTTATTCTAAGCGGATTTATTTTATACATGATATTAATTTTTACTCTA
    TCTATGATTGTTAATATTCACATCGTGTGGATTATCGCTTTAGCTATCGGTCTAATGTAT
    GGCATCTTATTACCAGCATGGAATACCTTTATGGCACGATTTATCAAATCAGATGAACAA
    GAAGAAACTTGGGGTGTTTTTAATAGTATCCAAGGATTCGGCTCAATGATAGGGCCATTA
    TTTGGCGGATTAATTACACAATTTACCAACGATTTAAACAATACATTTTATTTCTCGGCA
    TTAATCTTTTTAGTCTTAGCTGTATTTTATGGAAGCTACTTTATAGCAAATAGAGAAAAA
    GCTAAGTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1209

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SA_RS04940 [old locus tag: SA0874 ]
  • symbol: SA_RS04940
  • description: MFS transporter
  • length: 402
  • theoretical pI: 9.80405
  • theoretical MW: 45416.3
  • GRAVY: 0.931343

Function[edit | edit source]

  • TIGRFAM:
    multidrug resistance protein (TIGR00880; HMM-score: 47.3)
    and 4 more
    Metabolism Transport and binding proteins Cations and iron carrying compounds H+ Antiporter protein (TIGR00900; HMM-score: 22.6)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids D-galactonate transporter (TIGR00893; HMM-score: 18.7)
    Metabolism Transport and binding proteins Other glycerol-3-phosphate transporter (TIGR00712; HMM-score: 16.2)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids phosphoglycerate transporter family protein (TIGR00881; HMM-score: 8.5)
  • TheSEED: see SA0874
  • PFAM:
    MFS (CL0015) MFS_1; Major Facilitator Superfamily (PF07690; HMM-score: 137.5)
    and 1 more
    MFS_1_like; MFS_1 like family (PF12832; HMM-score: 16.3)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 12
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.007922
    • TAT(Tat/SPI): 0.000126
    • LIPO(Sec/SPII): 0.001861
  • predicted transmembrane helices (TMHMM): 12

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MERFLYMQDSSLNNYANHKNFILMLIILFLMEFARGMYILSYINFLPTVTSIAVAITSLAFSIHFIADASTNFVIGFLLKKFGTKIVLTTGFILAFTSLFLVIWFPASPFVIIFSAMMLGIAVSPIWVIMLSSVEEDKRGKQMGYVYFSWLLGLLVGMVFMNLLIKVHPTRFAFMMSLVVLIAWILYYFVDVKLTNYNTRPVKAQLRQIVDVTKRHLLLFPGILLQGAAIAALVPILPTYATKVINVSTIEYTVAIIIGGIGCAVSMLFLSKLIDNRSRNFMYGVILSGFILYMILIFTLSMIVNIHIVWIIALAIGLMYGILLPAWNTFMARFIKSDEQEETWGVFNSIQGFGSMIGPLFGGLITQFTNDLNNTFYFSALIFLVLAVFYGSYFIANREKAK

Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]