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NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS06795 [old locus tag: SA1195 ]
  • pan locus tag?: SAUPAN003751000
  • symbol: SA_RS06795
  • pan gene symbol?: msrR
  • synonym:
  • product: regulatory protein MsrR

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SA_RS06795 [old locus tag: SA1195 ]
  • symbol: SA_RS06795
  • product: regulatory protein MsrR
  • replicon: chromosome
  • strand: +
  • coordinates: 1366983..1367966
  • length: 984
  • essential: no DEG other strains

Accession numbers[edit | edit source]

  • Location: NC_002745 (1366983..1367966) NCBI
  • BioCyc: SA_RS06795 BioCyc
  • MicrobesOnline: see SA1195

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGGATAAAGAAACTAATGACAACGAATATAGACGTCAAAGTGAACATCGCACTTCGGCG
    CCTAAGCGAAAAAAGAAGAAGAAAATTAGGAAATTACCTATCATTCTTCTGATTGTTGTA
    ATTTTACTTATCGCATTAGTTGTATATATTGTACATAGTTACAATAGCGGTGTAGAATAT
    GCCAAGAAACATGCGAAAGATGTTAAAGTACATCAATTTAATGGACCAGTAAAAAATGAT
    GGTAAAATTTCTATTCTTGTACTCGGTGCAGATAAAGCACAAGGTGGACAATCAAGAACA
    GATTCTATCATGGTTGTTCAATATGACTTTATCAATAAAAAAATGAAAATGATGTCTGTC
    ATGCGTGATATTTATGCAGATATTCCAGGATATGGAAAACACAAAATTAATTCAGCATAC
    GCTTTAGGTGGTCCAGAGCTACTTAGAAAAACACTTGATAAAAATTTAGGAATTAATCCT
    GAATATTATGCAGTAGTTGATTTTACTGGATTTGAGAAAATGATTGATGAATTAATGCCA
    GAAGGTGTACCAATTAATGTCGAAAAGGATATGTCGAAAAATATTGGTGTATCTTTGAAA
    AAGGGTAACCATAGGTTGAATGGTAAAGAATTACTTGGTTATGCAAGATTCCGTCACGAC
    CCTGAAGGTGACTTCGGACGCGTGCGACGTCAGCAACAAGTGATGCAAACATTGAAAAAA
    GAAATGGTTAATTTTAGAACAGTTGTTAAATTACCAAAAGTTGCAGGTATTTTAAGAGGC
    TATGTGAATACAAACATTCCTGATTCAGGGATTTTCCAAACAGGTTTGAGTTTTGGCATC
    CGAGGTGAAAAAGATGTTAAGTCATTGACTGTGCCAATCAAGAACTCATACGAAGATGTC
    AATACAAATACTGATGGTAGTGCATTACAGATTAATAAAAACACAAATAAACAAGCTATT
    AAAGACTTTTTAGATGAAGATTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    984

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SA_RS06795 [old locus tag: SA1195 ]
  • symbol: SA_RS06795
  • description: regulatory protein MsrR
  • length: 327
  • theoretical pI: 10.2483
  • theoretical MW: 36970.5
  • GRAVY: -0.514679

Function[edit | edit source]

  • TIGRFAM:
    Signal transduction Regulatory functions Other cell envelope-related function transcriptional attenuator common domain (TIGR00350; HMM-score: 117.4)
    and 3 more
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type VII secretion protein EssA (TIGR03927; HMM-score: 15)
    Cellular processes Cellular processes Pathogenesis type II secretion system protein G (TIGR01710; HMM-score: 8.2)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type II secretion system protein G (TIGR01710; HMM-score: 8.2)
  • TheSEED: see SA1195
  • PFAM:
    no clan defined LytR_cpsA_psr; Cell envelope-related transcriptional attenuator domain (PF03816; HMM-score: 170.4)
    and 7 more
    DUF929; Domain of unknown function (DUF929) (PF06053; HMM-score: 16)
    DUF3671; Protein of unknown function (PF12420; HMM-score: 15.4)
    DUF5383; Family of unknown function (DUF5383) (PF17355; HMM-score: 15)
    Zn_Beta_Ribbon (CL0167) DUF2116; Uncharacterized protein containing a Zn-ribbon (DUF2116) (PF09889; HMM-score: 14)
    no clan defined DUF1510; Protein of unknown function (DUF1510) (PF07423; HMM-score: 12.7)
    Orf78; Orf78 (ac78) (PF06024; HMM-score: 12.6)
    Baculo_11_kDa; Baculovirus 11 kDa family (PF06143; HMM-score: 9.9)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.17
    • Cytoplasmic Membrane Score: 9.51
    • Cellwall Score: 0.16
    • Extracellular Score: 0.15
    • Internal Helix: 1
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.057495
    • TAT(Tat/SPI): 0.000446
    • LIPO(Sec/SPII): 0.002712
  • predicted transmembrane helices (TMHMM): 1

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MDKETNDNEYRRQSEHRTSAPKRKKKKKIRKLPIILLIVVILLIALVVYIVHSYNSGVEYAKKHAKDVKVHQFNGPVKNDGKISILVLGADKAQGGQSRTDSIMVVQYDFINKKMKMMSVMRDIYADIPGYGKHKINSAYALGGPELLRKTLDKNLGINPEYYAVVDFTGFEKMIDELMPEGVPINVEKDMSKNIGVSLKKGNHRLNGKELLGYARFRHDPEGDFGRVRRQQQVMQTLKKEMVNFRTVVKLPKVAGILRGYVNTNIPDSGIFQTGLSFGIRGEKDVKSLTVPIKNSYEDVNTNTDGSALQINKNTNKQAIKDFLDED

Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]