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NCBI: 26-AUG-2013

Summary[edit source | edit]

  • organism: Staphylococcus aureus N315
  • locus tag: SA1170 [new locus tag: SA_RS06645 ]
  • pan locus tag?: SAUPAN003707000
  • symbol: katA
  • pan gene symbol?: katA
  • synonym:
  • product: catalase

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SA1170 [new locus tag: SA_RS06645 ]
  • symbol: katA
  • product: catalase
  • replicon: chromosome
  • strand: +
  • coordinates: 1332093..1333616
  • length: 1524
  • essential: no DEG other strains

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    ATGACTATGTCACAACAAGACAAAAAGTTAACTGGTGTTTTTGGGCATCCAGTATCAGAC
    CGAGAAAATAGTATGACAGCAGGGCCTAGGGGACCTCTTTTAATGCAAGATATTTACTTT
    TTAGAGCAAATGTCTCAATTTGATAGAGAAGTAATACCAGAACGTCGAATGCATGCCAAA
    GGTTCTGGTGCATTTGGGACATTTACTGTAACTAAAGATATAACAAAATATACGAATGCT
    AAAATATTCTCTGAAATAGGTAAGCAAACCGAAATGTTTGCCCGTTTCTCTACTGTAGCA
    GGAGAACGTGGTGCTGCTGATGCGGAGCGTGACATTCGAGGATTTGCGTTAAAGTTCTAC
    ACTGAAGAAGGGAACTGGGATTTAGTAGGGAATAACACACCAGTATTCTTCTTTAGAGAT
    CCAAAGTTATTTGTTAGTTTAAATCGTGCGGTGAAACGAGATCCTAGAACAAATATGAGA
    GATGCACAAAATAACTGGGATTTCTGGACGGGTCTTCCAGAAGCATTGCACCAAGTAACG
    ATCTTAATGTCAGATAGAGGGATTCCTAAAGATTTACGTCATATGCATGGGTTCGGTTCT
    CACACATACTCTATGTATAATGATTCTGGTGAACGTGTTTGGGTTAAATTCCATTTTAGA
    ACGCAACAAGGTATTGAAAACTTAACTGATGAAGAAGCTGCTGAAATTATAGCTACAGAT
    CGTGATTCATCTCAACGCGATTTATTCGAAGCCATTGAAAAAGGTGATTATCCAAAATGG
    ACAATGTATATTCAAGTAATGACTGAGGAACAAGCTAAAAACCATAAAGATAATCCATTT
    GATTTAACAAAAGTATGGTATCACGATGAGTATCCTCTAATTGAAGTTGGAGAGTTTGAA
    TTAAATAGAAATCCAGATAATTACTTTATGGATGTTGAACAAGCTGCGTTTGCACCAACT
    AATATTATTCCAGGATTAGATTTTTCTCCAGACAAAATGTTGCAAGGGCGTTTATTCTCA
    TATGGCGATGCGCAAAGATATCGATTAGGAGTTAATCATTGGCAGATTCCTGTAAACCAA
    CCTAAAGGTGTTGGTATTGAAAATATTTGTCCTTTTAGTAGAGATGGTCAAATGCGCGTA
    GTTGACAATAACCAAGGTGGAGGAACACATTATTATCCAAATAACCATGGTAAATTTGAT
    TCTCAACCTGAATATAAAAAGCCACCATTCCCAACTGATGGATACGGCTATGAATATAAT
    CAACGTCAAGATGATGATAATTATTTTGAACAACCAGGTAAATTGTTTAGATTACAATCA
    GAGGACGCTAAAGAAAGAATTTTTACAAATACAGCAAATGCAATGGAAGGCGTAACGGAT
    GATGTTAAACGACGTCATATTCGTCATTGTTACAAAGCTGACCCAGAATATGGTAAAGGT
    GTTGCAAAAGCATTAGGTATTGATATAAATTCTATTGATCTTGAAACTGAAAATGATGAA
    ACATACGAAAACTTTGAAAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1524

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SA1170 [new locus tag: SA_RS06645 ]
  • symbol: KatA
  • description: catalase
  • length: 507
  • theoretical pI: 5.13252
  • theoretical MW: 58611.8
  • GRAVY: -0.840039

Function[edit source | edit]

  • reaction:
    EC 1.11.1.6?  ExPASy
    Catalase2 H2O2 = O2 + 2 H2O
  • TIGRFAM:
  • TheSEED:  
    Oxidative stress Catalase KatE (EC 1.11.1.6) 
    Protection from Reactive Oxygen Species Catalase KatE (EC 1.11.1.6) 
  • PFAM:
    no clan definedCatalase; Catalase (PF00199; HMM-score: 606.9)
    Catalase-rel; Catalase-related immune-responsive (PF06628; HMM-score: 80.3)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors: heme
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular Possibility: 1
    • Signal Peptide Possibility: -1
    • N-terminally Anchored Score: -1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • Ymax: 0.132
    • Ymax_pos: 11
    • Cmax: 0.106
    • Cmax_pos: 27
    • Smax: 0.252
    • Smax_pos: 1
    • Smean: 0.157
    • D: 0.142
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

Protein sequence[edit source | edit]

  • MTMSQQDKKLTGVFGHPVSDRENSMTAGPRGPLLMQDIYFLEQMSQFDREVIPERRMHAKGSGAFGTFTVTKDITKYTNAKIFSEIGKQTEMFARFSTVAGERGAADAERDIRGFALKFYTEEGNWDLVGNNTPVFFFRDPKLFVSLNRAVKRDPRTNMRDAQNNWDFWTGLPEALHQVTILMSDRGIPKDLRHMHGFGSHTYSMYNDSGERVWVKFHFRTQQGIENLTDEEAAEIIATDRDSSQRDLFEAIEKGDYPKWTMYIQVMTEEQAKNHKDNPFDLTKVWYHDEYPLIEVGEFELNRNPDNYFMDVEQAAFAPTNIIPGLDFSPDKMLQGRLFSYGDAQRYRLGVNHWQIPVNQPKGVGIENICPFSRDGQMRVVDNNQGGGTHYYPNNHGKFDSQPEYKKPPFPTDGYGYEYNQRQDDDNYFEQPGKLFRLQSEDAKERIFTNTANAMEGVTDDVKRRHIRHCYKADPEYGKGVAKALGIDINSIDLETENDETYENFEK

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

Regulation[edit source | edit]

  • sigma factor:
  • regulators: SA1678 (PerR*), CodY
    PerR* (TF) important in Oxidative stress response  RegPrecise
    CodY (TF) important in Amino acid metabolism  RegPrecise

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]