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NCBI: 26-AUG-2013

Summary[edit source | edit]

  • organism: Staphylococcus aureus N315
  • locus tag: SA1393
  • pan locus tag?: SAUPAN004145000
  • symbol: SA1393
  • pan gene symbol?: ccpN
  • synonym:
  • product: hypothetical protein

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SA1393
  • symbol: SA1393
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1599418..1600041
  • length: 624
  • essential: no DEG other strains

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    ATAGAACTCAGTCAAAGACAAGAACGAATCATCGAAATTGTTAAAACTAAAGGACCCATT
    ACTGGTGAACAAATAGCAGATAAGTTGAATTTAACAAGAGCAACGCTTAGACCAGATTTA
    GCGATATTAACAATGTCAGGTTTTTTAGAAGCGCGTCCCCGAGTTGGATATTATTATTCA
    GGTAAATCAAAAGGCAAATTTTTTAATGAAAAACTTCGACAATTTGAGGTTAAGGACTAT
    ATGTCTCAACCTGTTGTGCTAAGAGAGAATACAACAGTTTATGACGCTATTTGTACAATT
    TTTTTAGAAGATGTAAGTACATTATTTATTATTAATGAAGATAACGATTTTGTTGGTGTG
    TGTTCAAGAAAAGATTTATTAAGAGCTTCAATGATTGGAGCAGATATTCATACAGTACCT
    ATCAGTGTAAATATGACACGTATGCCTAATGTCACTTATTTAGAGGAAAGCGAATTAGTC
    ATATACGCAGCAGATAGAATGATTGAAAAAGAAATTGATTCGATTCCAATTGTAAGAAAA
    AAAGATAATCAAAAGTATGAAGTAATTGGAAGAATTTCCAAAACAACAATAGCTAAGTTA
    TTAGTAGCATTATATAAAGAATAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    624

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SA1393
  • symbol: SA1393
  • description: hypothetical protein
  • length: 207
  • theoretical pI: 8.1547
  • theoretical MW: 23708.4
  • GRAVY: -0.17971

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    MetabolismEnergy metabolismSugarssugar isomerase, KpsF/GutQ family (TIGR00393; HMM-score: 27.9)
    MetabolismPurines, pyrimidines, nucleosides, and nucleotidesPurine ribonucleotide biosynthesisinosine-5'-monophosphate dehydrogenase (TIGR01302; EC 1.1.1.205; HMM-score: 18.7)
    Signal transductionRegulatory functionsDNA interactionsCRISPR locus-related DNA-binding protein (TIGR01884; HMM-score: 17.9)
    MetabolismAmino acid biosynthesisSerine familycystathionine beta-synthase (TIGR01137; EC 4.2.1.22; HMM-score: 14.1)
  • TheSEED:  
    Transcriptional repressor CcpN, MarR family 
  • PFAM:
    no clan definedCBS; CBS domain (PF00571; HMM-score: 54.4)
    HTH (CL0123) HTH_11; HTH domain (PF08279; HMM-score: 49.5)
    HTH_DeoR; DeoR-like helix-turn-helix domain (PF08220; HMM-score: 25.6)
    MarR; MarR family (PF01047; HMM-score: 20.4)
    HTH_24; Winged helix-turn-helix DNA-binding (PF13412; HMM-score: 16.5)
    HTH_Mga; M protein trans-acting positive regulator (MGA) HTH domain (PF08280; HMM-score: 15.4)
    GntR; Bacterial regulatory proteins, gntR family (PF00392; HMM-score: 14.2)
    Sigma70_r4; Sigma-70, region 4 (PF04545; HMM-score: 13.6)
    TFIIE_alpha; TFIIE alpha subunit (PF02002; HMM-score: 13.6)
    HTH_20; Helix-turn-helix domain (PF12840; HMM-score: 13.1)
    DUF977; Bacterial protein of unknown function (DUF977) (PF06163; HMM-score: 12.8)
    HTH_7; Helix-turn-helix domain of resolvase (PF02796; HMM-score: 12.6)
    HTH_Crp_2; Crp-like helix-turn-helix domain (PF13545; HMM-score: 12.2)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular Possibility: 1
    • Signal Peptide Possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • Ymax: 0.116
    • Ymax_pos: 11
    • Cmax: 0.123
    • Cmax_pos: 52
    • Smax: 0.214
    • Smax_pos: 5
    • Smean: 0.145
    • D: 0.127
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

Protein sequence[edit source | edit]

  • MELSQRQERIIEIVKTKGPITGEQIADKLNLTRATLRPDLAILTMSGFLEARPRVGYYYSGKSKGKFFNEKLRQFEVKDYMSQPVVLRENTTVYDAICTIFLEDVSTLFIINEDNDFVGVCSRKDLLRASMIGADIHTVPISVNMTRMPNVTYLEESELVIYAADRMIEKEIDSIPIVRKKDNQKYEVIGRISKTTIAKLLVALYKE

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]