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NCBI: 26-AUG-2013

Summary[edit source | edit]

  • organism: Staphylococcus aureus N315
  • locus tag: SA2293 [new locus tag: SA_RS13150 ]
  • pan locus tag?: SAUPAN006130000
  • symbol: gntP
  • pan gene symbol?: gntP
  • synonym:
  • product: gluconate permease

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SA2293 [new locus tag: SA_RS13150 ]
  • symbol: gntP
  • product: gluconate permease
  • replicon: chromosome
  • strand: -
  • coordinates: 2575474..2576832
  • length: 1359
  • essential: no DEG other strains

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    ATGTTTAACGAAATATGGCCGTTAATCAGTGTTGTTTTAGGTATCGTTATTTTATTAGTA
    TTAATTATTGGGTTTAAATTAAATACATTTATTTCATTAATTATCACATCGATGATTACA
    GCGTTAATGCTAGGTATACCATTGACTAAAATTATGGAGACGATTGAGAAAGGGATGGGC
    AGTACGCTCGGCCACATTGCACTAATATTCGGTTTAGGTGCCATACTTGGGAAATTACTT
    GCTGATGGTGGTGGTGCAACTCGAATTGCAGACACGTTGATTCAAAAATTTGGTCAAAAA
    CATGTACAATGGGCAATGCTTGTTGCAGCATTTATCGTCGGTATTGCATTGTTCTTTGAA
    GTAGGTTTAGTCTTACTGATTCCATTAGTATTTACAGTAGCAAAACGCGCAAATGTTTCA
    GTGTTAAAACTAGGACTACCTATGGTAACAGCTTTATCTGTGACACATGGCTTTTTACCA
    CCACATCCAGGACCGGTAGTCATCGCAAAAGAATTAAAGGCAAATGTTGGAGATGTATTA
    CTGTACGGTATGATTATTGCCATTCCAGTTACACTCATTGCAGGACCTATATTTAACAAA
    GTTGCACAAAAAATGATTCCGTCTGCGTATACACGAGAAGGCGATATTTCAGCGTTAGGT
    GCACAAAAAGAATTTACGGATCAAGAGATGCCAGGATTTGGTATGAGTTTATTAACTGCA
    ACATTACCAGTCATATTAATGTTAGTGTCTACGATAACGCAACTTGTAACTGGGCACGAC
    AAACCTACAAATCTATTTGAATCTATCATTTATATGATAGGAACAGCAGGGACAGCCATG
    CTAATAGCAGTATTATTTGCAATCGTTACGATGGGATTAATGAGAAAACGTAAGATGAAT
    CATATTATGGAATCAGTGACGAATGCGATTTATCCAATCGGAATGATGTTATTGATTATT
    GGCGGTGGCGGTACATTTAAACAAGTATTAATTGACGGTGGTGTCGGAAATACAATTGCT
    AAAATGTTTGAAGGTACAGAGATGTCTCCAATTTTACTAGCATGGATTGTTGCAGCTGTG
    CTACGTATCGCATTAGGTTCGGCTACAGTAGCTGCGATTTCAACTACAGGTATTGTCTTA
    CCATTATTACAATCATCAGATGTAAATGTTGCATTAGTTGTACTTGCGATAGGTGCAGGT
    AGTGTGATTTTGTCTCATGTAAATGACGCAGGATTTTGGATGTTTAAAGAATATTTTGGT
    TTAACTGTAAAAGAAACATTCTTAACATGGTCATTATTAGAAACGATTATTTCCGTTTCA
    GGTATCATCTTCATTCTATTCATCAGCTTATTTGTTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1359

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SA2293 [new locus tag: SA_RS13150 ]
  • symbol: GntP
  • description: gluconate permease
  • length: 452
  • theoretical pI: 9.2587
  • theoretical MW: 48102.9
  • GRAVY: 1.02942

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    MetabolismTransport and binding proteinsCarbohydrates, organic alcohols, and acidstransporter, gluconate:H+ symporter (GntP) family (TIGR00791; HMM-score: 600.4)
  • TheSEED:  
    CarbohydratesMonosaccharidesD-gluconate and ketogluconates metabolism Gluconate permease, Bsu4004 homolog 
  • PFAM:
    IT (CL0182) GntP_permease; GntP family permease (PF02447; HMM-score: 570.6)
    CitMHS; Citrate transporter (PF03600; HMM-score: 72.3)
    Na_H_antiport_2; Na+-H+ antiporter family (PF13726; HMM-score: 16.9)
    no clan definedTim17; Tim17/Tim22/Tim23/Pmp24 family (PF02466; HMM-score: 10.6)
    IT (CL0182) DctM; Tripartite ATP-independent periplasmic transporter, DctM component (PF06808; HMM-score: 7.8)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 12
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular Possibility: 0.17
    • Signal Peptide Possibility: -1
    • N-terminally Anchored Score: -1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • Ymax: 0.101
    • Ymax_pos: 11
    • Cmax: 0.122
    • Cmax_pos: 29
    • Smax: 0.162
    • Smax_pos: 3
    • Smean: 0.099
    • D: 0.1
  • predicted transmembrane helices (TMHMM): 12

Accession numbers[edit source | edit]

  • GI: 15928084 NCBI
  • RefSeq: NP_375617 NCBI
  • UniProt:

Protein sequence[edit source | edit]

  • MFNEIWPLISVVLGIVILLVLIIGFKLNTFISLIITSMITALMLGIPLTKIMETIEKGMGSTLGHIALIFGLGAILGKLLADGGGATRIADTLIQKFGQKHVQWAMLVAAFIVGIALFFEVGLVLLIPLVFTVAKRANVSVLKLGLPMVTALSVTHGFLPPHPGPVVIAKELKANVGDVLLYGMIIAIPVTLIAGPIFNKVAQKMIPSAYTREGDISALGAQKEFTDQEMPGFGMSLLTATLPVILMLVSTITQLVTGHDKPTNLFESIIYMIGTAGTAMLIAVLFAIVTMGLMRKRKMNHIMESVTNAIYPIGMMLLIIGGGGTFKQVLIDGGVGNTIAKMFEGTEMSPILLAWIVAAVLRIALGSATVAAISTTGIVLPLLQSSDVNVALVVLAIGAGSVILSHVNDAGFWMFKEYFGLTVKETFLTWSLLETIISVSGIIFILFISLFV

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

Regulation[edit source | edit]

  • sigma factor:
  • regulators: CcpA, GntR
    CcpA (TF) important in Carbon catabolismRegPrecise
    GntR (TF) important in Gluconate utilizationRegPrecise

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]