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Pangenome04-0298108BA0217611819-9771193COLECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50N315NCTC8325NewmanRF122ST398T0131TCH60TW20USA300_FPR3757USA300_TCH1516VC40
NCBI: 02-MAR-2017

Summary[edit source | edit]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL_RS01890 [old locus tag: SACOL0376 ]
  • pan locus tag?: SAUPAN001825000
  • symbol: SACOL_RS01890
  • pan gene symbol?:
  • synonym:
  • product: tail protein

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SACOL_RS01890 [old locus tag: SACOL0376 ]
  • symbol: SACOL_RS01890
  • product: tail protein
  • replicon: chromosome
  • strand: +
  • coordinates: 381346..381801
  • length: 456
  • essential: unknown

Accession numbers[edit source | edit]

  • Location: NC_002951 (381346..381801) NCBI
  • MicrobesOnline:

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    ATGACTAAAACTTTAAAGGTTTATAAAGGAGACGACGTCGTAGCTTCTGAACAAGGTGAA
    GGCAAAGTGTCAGTAACTTTATCTAATTTAGAAGCGGATACAACTTATCCAAAAGGTACT
    TACCAAGTGGCATGGGAAGAAAATGGTAAAGAATCTAGTAAAGTTGATGTACCTCAATTC
    AAAACCAATCCAATTCTAGTCTCAGGCGTATCATTTACACCAGAAACTAAATCAATTATG
    GTAAATACCGATGACAATGTTGAGCCAAACATTGCACCAAGCACAGCAACGAATAAAATA
    TTGAAATATACAAGTGAACATCCAGAATTTGTTACTGTAGATGAAAATACAGGAGCAATT
    CACGGTGTAGCTGAAGGTACTTCAGTAATCACTGCTATGTCTACTGATGGAAGCGATAAG
    TCAGGACAAATTTCAGTGACAGTAACAAACGGATAG
    60
    120
    180
    240
    300
    360
    420
    456

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SACOL_RS01890 [old locus tag: SACOL0376 ]
  • symbol: SACOL_RS01890
  • description: tail protein
  • length: 151
  • theoretical pI: 4.33262
  • theoretical MW: 16032.6
  • GRAVY: -0.435099

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    isopropylmalate/isohomocitrate dehydrogenases (TIGR02088; HMM-score: 12.6)
    streptococcal pilin isopeptide linkage domain (TIGR03786; HMM-score: 11)
  • TheSEED:
  • PFAM:
    E-set (CL0159) Big_2; Bacterial Ig-like domain (group 2) (PF02368; HMM-score: 36.2)
    Pur_ac_phosph_N; Purple acid Phosphatase, N-terminal domain (PF16656; HMM-score: 12.9)
    SprB; SprB repeat (PF13573; HMM-score: 8.2)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:
    SACOL_RS05630pyruvate dehydrogenase E1 component subunit alpha  [1] (data from MRSA252)
    SACOL_RS05640dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex  [1] (data from MRSA252)

Localization[edit source | edit]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • Ymax: 0.133
    • Ymax_pos: 33
    • Cmax: 0.178
    • Cmax_pos: 33
    • Smax: 0.235
    • Smax_pos: 14
    • Smean: 0.122
    • D: 0.129
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

  • GI: 446091272 NCBI
  • RefSeq: WP_000169127 NCBI
  • UniProt:

Protein sequence[edit source | edit]

  • MTKTLKVYKGDDVVASEQGEGKVSVTLSNLEADTTYPKGTYQVAWEENGKESSKVDVPQFKTNPILVSGVSFTPETKSIMVNTDDNVEPNIAPSTATNKILKYTSEHPEFVTVDENTGAIHGVAEGTSVITAMSTDGSDKSGQISVTVTNG

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • SACOL_RS01890 no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

  1. 1.0 1.1 Artem Cherkasov, Michael Hsing, Roya Zoraghi, Leonard J Foster, Raymond H See, Nikolay Stoynov, Jihong Jiang, Sukhbir Kaur, Tian Lian, Linda Jackson, Huansheng Gong, Rick Swayze, Emily Amandoron, Farhad Hormozdiari, Phuong Dao, Cenk Sahinalp, Osvaldo Santos-Filho, Peter Axerio-Cilies, Kendall Byler, William R McMaster, Robert C Brunham, B Brett Finlay, Neil E Reiner
    Mapping the protein interaction network in methicillin-resistant Staphylococcus aureus.
    J. Proteome Res.: 2011, 10(3);1139-50
    [PubMed:21166474] [WorldCat.org] [DOI] (I p)

Relevant publications[edit source | edit]