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NCBI: 02-MAR-2017

Summary[edit source | edit]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL_RS10070 [old locus tag: SACOL1926 ]
  • pan locus tag?: SAUPAN004850000
  • symbol: SACOL_RS10070
  • pan gene symbol?: mutY
  • synonym:
  • product: A/G-specific adenine glycosylase

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SACOL_RS10070 [old locus tag: SACOL1926 ]
  • symbol: SACOL_RS10070
  • product: A/G-specific adenine glycosylase
  • replicon: chromosome
  • strand: -
  • coordinates: 1990591..1991628
  • length: 1038
  • essential: unknown

Accession numbers[edit source | edit]

  • Location: NC_002951 (1990591..1991628) NCBI
  • MicrobesOnline:

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGTATCAGCAGTCTAGTTTTAAAGAAAATTTGATACACTGGTTTGATGAAAATCAAAGA
    GAAATGCCATGGCGACAAACGACCAATCCGTACTATATTTGGTTAAGTGAGGTCATGTTA
    CAACAGACACAAGTTAAAACAGTTATTGACTATTATCATCGTTTTGTTGAACGATTTCCA
    ACTGTGGAAGTTTTGAGTCAAGCTTCGGAAGATGAAGTGTTAAAGTATTGGGAAGGCTTA
    GGATATTATAGTAGAGCTCGAAATTTTCATACGGCGATTAAAGAAGTTCATGATAAATAT
    GAAGGCTTAGTTCCCAAAGATCCTGATCAATTTAAAGCGTTAAAAGGTGTTGGCCCATAC
    ACACAAGCTGCAGTAATGAGCATTGCATATAATGTACCACTAGCAACTGTAGACGGAAAT
    GTTTTTCGAGTATGGTCTAGATTGAATGATGACTATCGAGATATTAAATTACAATCGACG
    AGGAAATCGTACGAACAAGAATTATTACCGTATGTTACTACAGAAGCTGGAACGTTTAAT
    CAAGCTATGATGGAATTAGGGGCGTTAATTTGTACACCAAAAAATCCATTATGCTTATTT
    TGTCCAGTTCAAGAAAACTGTGAGGCATTTGATAAAGGTACATTTGAAAAGTTACCTGTT
    AAATCTAAAAATGTAAGTAAAAAAGTAATTGAGCAATCCGTCTTTTTAATTAGAAATAAT
    CAAGGTCAATATCTGTTGCAAAAGCGTAGCGAAAAATTATTGCATGGTATGTGGCAATTT
    CCTATGTTTGAAAGTGAGCATGCTAGACGTAAAATGACTGAAAAAATCGGTCATGACATT
    CAACCAGTAGAAACACCTATTTTTGAGTTGAAGCATCAATTTACTCATTTAACATGGAAG
    ATTAAAGTATACGCCGTTTCAGGAGCAATTAACATTGAAACATTACCAGATGACATGATT
    TGGTTTGATTTAAGTGATCGAGATCAATATACATTCCCTGTACCTATGTCAAAGATTTAT
    CAATTTATAAATGGGTAA
    60
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    1020
    1038

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SACOL_RS10070 [old locus tag: SACOL1926 ]
  • symbol: SACOL_RS10070
  • description: A/G-specific adenine glycosylase
  • length: 345
  • theoretical pI: 6.79462
  • theoretical MW: 40623.2
  • GRAVY: -0.495652

Function[edit source | edit]

  • reaction:
    EC 3.2.2.-?  ExPASy
  • TIGRFAM:
    Genetic information processingDNA metabolismDNA replication, recombination, and repairA/G-specific adenine glycosylase (TIGR01084; EC 3.2.2.-; HMM-score: 328.3)
    Genetic information processingDNA metabolismDNA replication, recombination, and repairendonuclease III (TIGR01083; EC 4.2.99.18; HMM-score: 74.1)
  • TheSEED:
  • PFAM:
    NUDIX (CL0261) NUDIX_4; NUDIX domain (PF14815; HMM-score: 78.6)
    HHH (CL0198) HhH-GPD; HhH-GPD superfamily base excision DNA repair protein (PF00730; HMM-score: 55.7)
    HHH; Helix-hairpin-helix motif (PF00633; HMM-score: 28.1)
    no clan definedEndIII_4Fe-2S; Iron-sulfur binding domain of endonuclease III (PF10576; HMM-score: 16.9)
    NUDIX (CL0261) NUDIX; NUDIX domain (PF00293; HMM-score: 15.4)
    no clan definedNDUFB10; NADH-ubiquinone oxidoreductase subunit 10 (PF10249; HMM-score: 12.9)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • Ymax: 0.1
    • Ymax_pos: 69
    • Cmax: 0.119
    • Cmax_pos: 69
    • Smax: 0.113
    • Smax_pos: 68
    • Smean: 0.066
    • D: 0.087
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

  • GI: 446206897 NCBI
  • RefSeq: WP_000284752 NCBI
  • UniProt:

Protein sequence[edit source | edit]

  • MYQQSSFKENLIHWFDENQREMPWRQTTNPYYIWLSEVMLQQTQVKTVIDYYHRFVERFPTVEVLSQASEDEVLKYWEGLGYYSRARNFHTAIKEVHDKYEGLVPKDPDQFKALKGVGPYTQAAVMSIAYNVPLATVDGNVFRVWSRLNDDYRDIKLQSTRKSYEQELLPYVTTEAGTFNQAMMELGALICTPKNPLCLFCPVQENCEAFDKGTFEKLPVKSKNVSKKVIEQSVFLIRNNQGQYLLQKRSEKLLHGMWQFPMFESEHARRKMTEKIGHDIQPVETPIFELKHQFTHLTWKIKVYAVSGAINIETLPDDMIWFDLSDRDQYTFPVPMSKIYQFING

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • SACOL_RS10070 no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]