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NCBI: 03-AUG-2016

Summary[edit source | edit]

  • organism: Staphylococcus aureus NCTC8325
  • locus tag: SAOUHSC_01641
  • pan locus tag?: SAUPAN004122000
  • symbol: SAOUHSC_01641
  • pan gene symbol?: comGB
  • synonym:
  • product: hypothetical protein

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SAOUHSC_01641
  • symbol: SAOUHSC_01641
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1558274..1559194
  • length: 921
  • essential: no DEG other strains

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGACATATAAAAATAAGCAATTAGGTACCACCATTCTAAGTGAAATTTCAAATGGTGCA
    CCATGCAATCAAATATTATCACTGATAGGTTATAGCGATACTATCGTCATGCAAGTATAT
    TTGGCAGAAAGATTTGGCAATATTATAGACGTTCTAGAAGAAACCGTAAATTATATGAAA
    GTGAATAGAAAGTCAGAACAACGATTGTTAAAGACACTGCAATACCCCTTAATACTAGTT
    TCTATCTTTATTGCTATGATTATTATATTAAACCTCACAGTAATTCCACAGTTTCAACAA
    TTATATACTTCTATGAATATTCAACTATCTTCTTTTCAAAAAACATTGTCTTTTTTCATT
    ACCAGCTTACCTACTATAATTGTAGTAATGCTCATAATAGTATCTATGTTGGCTATTATT
    ATGAAATTAATTTATAACAATTTAAATATGCTCAATAAGATAAACTTTGTGATGAAACTA
    CCGCTAATATCAGGCTATTTCCAATTATTTAAAACTTATTTTGTAACTAATGAATTAGTG
    TTGTTTTATAAAAATGGTATTACACTTCAATCAATAGTAGACGTTTATATTAACCATAGT
    AGTGATCCATTTAGACAGTTTCTAGGTAAATACTTATTAACTTATTCAGAAATGGGATAT
    GGTTTGCCTCAAATTTTAGAAAAACTAAAATGCTTTAAGCCTCAATTAATTAAGTTTGTG
    CTACAAGGTGAAAAGAGAGGGAAGCTAGAAGTAGAACTAAAGTTATATTCGCAAATATTA
    GTAAAACAAATAGAAGATAAAGCGATAAAACAGACTCAGTTTTTACAGCCTATTTTATTT
    TTGATTTTAGGTTTATTTATTGTCGCAATTTATTTAGTAATTATGTTACCAATGTTTCAA
    ATGATGCAAAGTATAAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    921

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SAOUHSC_01641
  • symbol: SAOUHSC_01641
  • description: hypothetical protein
  • length: 306
  • theoretical pI: 9.85354
  • theoretical MW: 35431.5
  • GRAVY: 0.510458

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    Genetic information processingProtein fateProtein and peptide secretion and traffickingtype II secretion system protein F (TIGR02120; HMM-score: 79.5)
  • TheSEED:  
    DNA MetabolismDNA uptake, competenceGram Positive Competence Late competence protein ComGB, access of DNA to ComEA 
    DNA uptake, competenceLate competence Late competence protein ComGB, access of DNA to ComEA 
  • PFAM:
    no clan definedT2SSF; Type II secretion system (T2SS), protein F (PF00482; HMM-score: 74.5)
    E1-E2_ATPase; E1-E2 ATPase (PF00122; HMM-score: 9.7)
    Tetraspannin (CL0347) DUF4064; Protein of unknown function (DUF4064) (PF13273; HMM-score: 6.8)
    no clan definedDUF2207; Predicted membrane protein (DUF2207) (PF09972; HMM-score: 6.2)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 3
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular Possibility: 0.17
    • Signal Peptide Possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • Ymax: 0.13
    • Ymax_pos: 20
    • Cmax: 0.125
    • Cmax_pos: 42
    • Smax: 0.236
    • Smax_pos: 2
    • Smean: 0.169
    • D: 0.145
  • predicted transmembrane helices (TMHMM): 3

Accession numbers[edit source | edit]

Protein sequence[edit source | edit]

  • MTYKNKQLGTTILSEISNGAPCNQILSLIGYSDTIVMQVYLAERFGNIIDVLEETVNYMKVNRKSEQRLLKTLQYPLILVSIFIAMIIILNLTVIPQFQQLYTSMNIQLSSFQKTLSFFITSLPTIIVVMLIIVSMLAIIMKLIYNNLNMLNKINFVMKLPLISGYFQLFKTYFVTNELVLFYKNGITLQSIVDVYINHSSDPFRQFLGKYLLTYSEMGYGLPQILEKLKCFKPQLIKFVLQGEKRGKLEVELKLYSQILVKQIEDKAIKQTQFLQPILFLILGLFIVAIYLVIMLPMFQMMQSIK

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

  1. Ulrike Mäder, Pierre Nicolas, Maren Depke, Jan Pané-Farré, Michel Debarbouille, Magdalena M van der Kooi-Pol, Cyprien Guérin, Sandra Dérozier, Aurelia Hiron, Hanne Jarmer, Aurélie Leduc, Stephan Michalik, Ewoud Reilman, Marc Schaffer, Frank Schmidt, Philippe Bessières, Philippe Noirot, Michael Hecker, Tarek Msadek, Uwe Völker, Jan Maarten van Dijl
    Staphylococcus aureus Transcriptome Architecture: From Laboratory to Infection-Mimicking Conditions.
    PLoS Genet.: 2016, 12(4);e1005962
    [PubMed:27035918] [WorldCat.org] [DOI] (I e)

Relevant publications[edit source | edit]