NCBI: 02-MAR-2017

⊟Summary

• organism: Staphylococcus aureus N315
• locus tag: SA_RS05345 [old locus tag: SA0943 ]
• pan locus tag^?: SAUPAN003316000
• symbol: SA_RS05345
• pan gene symbol^?: —
• synonym:
• product: cell-wall-binding lipoprotein

⊟Gene

⊟General

• type: CDS
• locus tag: SA_RS05345 [old locus tag: SA0943 ]
• symbol: SA_RS05345
• product: cell-wall-binding lipoprotein
• replicon: chromosome
• strand: +
• coordinates: 1070045..1070671
• length: 627
• essential: unknown

⊟Accession numbers

• Location: NC_002745 (1070045..1070671) NCBI
• BioCyc: G1G21-1077 BioCyc
• MicrobesOnline:

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

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  ATGAAATTTGGAAAAACAATCGCAGTAGTATTAGCATCTAGTGTCTTGCTTGCAGGATGT
  ACTACGGATAAAAAAGAAATTAAGGCATATTTAAAGCAAGTGGATAAAATTAAAGACGAT
  GAAGAACCAATTAAAACTGTTGGTAAGAAAATTGCTGAATTAGATGAGAAAAAGAAAAAA
  TTAACTGAAGATGTCAATAGTAAAGATACAGCAGTTCGCGGTAAAGCAGTAAAAGATTTA
  ATTAAAAATGCCGATGATCGTCTAAAGGAATTTGAAAAAGAAGAAGACGCAATTAAGAAG
  TCTGAACAAGACTTTAAGAAAGCAAAAAGTCACGTTGATAACATTGATAATGATGTTAAA
  CGTAAAGAAGTAAAACAATTAGATGATGTATTAAAAGAAAAATACAAATTGCATGGTGAA
  TACGCGAAAGCATATAAAAAGGCTGTAAACTCAGAGAAAACATTATTTAAATATTTAAAT
  CAAAATGACGCGACACAACAAGGTGTTAACGAAAAATCAAAAGCAATAGAACAGAACTAT
  AAAAAGTTAAAAGAAGTATCAGATAAGTATACGAAAGTACTAAATAAGGTTGGTAAAGAA
  AAGCAAGACGTTGATCAATTTAAATAA
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⊟Protein

⊟General

• locus tag: SA_RS05345 [old locus tag: SA0943 ]
• symbol: SA_RS05345
• description: cell-wall-binding lipoprotein
• length: 208
• theoretical pI: 9.96393
• theoretical MW: 23859.2
• GRAVY: -1.06394

⊟Function

• TIGRFAM:
  Cellular processesCellular processesCell divisionchromosome segregation protein SMC (TIGR02169; HMM-score: 14.9)
  Genetic information processingDNA metabolismChromosome-associated proteinschromosome segregation protein SMC (TIGR02169; HMM-score: 14.9)
  type VII secretion effector, TIGR04197 family (TIGR04197; HMM-score: 12.8)
  and 6 more
  Cellular processesCellular processesBiosynthesis of natural productsNHLM bacteriocin system secretion protein (TIGR03794; HMM-score: 8.4)
  MetabolismTransport and binding proteinsAmino acids, peptides and aminesNHLM bacteriocin system secretion protein (TIGR03794; HMM-score: 8.4)
  SH3 domain protein (TIGR04211; HMM-score: 8.2)
  two transmembrane protein (TIGR04527; HMM-score: 8.1)
  Genetic information processingMobile and extrachromosomal element functionsPlasmid functionsconjugative transfer region lipoprotein, TIGR03751 family (TIGR03751; HMM-score: 6.3)
  phage lysis regulatory protein, LysB family (TIGR03495; HMM-score: 5)
• TheSEED:
• PFAM:
  no clan definedYkyA; Putative cell-wall binding lipoprotein (PF10368; HMM-score: 171.4)
  and 16 more
  Mce4_CUP1; Cholesterol uptake porter CUP1 of Mce4, putative (PF11887; HMM-score: 18.8)
  BORCS7; BLOC-1-related complex sub-unit 7 (PF16088; HMM-score: 13.1)
  BLOC1_2; Biogenesis of lysosome-related organelles complex-1 subunit 2 (PF10046; HMM-score: 12.1)
  TerB (CL0414) TerB; Tellurite resistance protein TerB (PF05099; HMM-score: 12)
  no clan definedEzrA; Septation ring formation regulator, EzrA (PF06160; HMM-score: 11.8)
  BCLiA (CL0551) APG6; Autophagy protein Apg6 (PF04111; HMM-score: 11.7)
  no clan definedDASH_Duo1; DASH complex subunit Duo1 (PF08651; HMM-score: 10.4)
  DUF3452; Domain of unknown function (DUF3452) (PF11934; HMM-score: 10.4)
  T3SSipB; Type III cell invasion protein SipB (PF16535; HMM-score: 10.4)
  DUF948; Bacterial protein of unknown function (DUF948) (PF06103; HMM-score: 9.9)
  IL31; Interleukin 31 (PF15209; HMM-score: 9.6)
  P-loop_NTPase (CL0023) AAA_13; AAA domain (PF13166; HMM-score: 8.8)
  Golgi-transport (CL0145) BAR_3; BAR domain of APPL family (PF16746; HMM-score: 7.6)
  no clan definedIncA; IncA protein (PF04156; HMM-score: 7)
  V_ATPase_I; V-type ATPase 116kDa subunit family (PF01496; HMM-score: 6.5)
  Med4; Vitamin-D-receptor interacting Mediator subunit 4 (PF10018; HMM-score: 6.5)

⊟Structure, modifications & interactions

• domains:
• modifications:
• cofactors:
• effectors:
• protein partners:

⊟Localization

• PSORTb: unknown (no significant prediction)
  • Cytoplasmic Score: 0
  • Cytoplasmic Membrane Score: 3.33
  • Cellwall Score: 3.33
  • Extracellular Score: 3.33
  • Internal Helices: 0
• LocateP:
• SignalP: Signal peptide length 26 aa
  • Ymax: 0.344
  • Ymax_pos: 26
  • Cmax: 0.2
  • Cmax_pos: 26
  • Smax: 0.793
  • Smax_pos: 6
  • Smean: 0.669
  • D: 0.471
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI: 446590990 NCBI
• RefSeq: WP_000668336 NCBI
• UniProt:

⊟Protein sequence

• MKFGKTIAVVLASSVLLAGCTTDKKEIKAYLKQVDKIKDDEEPIKTVGKKIAELDEKKKKLTEDVNSKDTAVRGKAVKDLIKNADDRLKEFEKEEDAIKKSEQDFKKAKSHVDNIDNDVKRKEVKQLDDVLKEKYKLHGEYAKAYKKAVNSEKTLFKYLNQNDATQQGVNEKSKAIEQNYKKLKEVSDKYTKVLNKVGKEKQDVDQFK

⊟Experimental data

• experimentally validated: no data available

⊟Expression & Regulation

⊟Operon

• SA_RS05345 no polycistronic organisation predicted

⊟Regulation

• sigma factor:
• regulator:

⊟Transcription pattern

• S.aureus Expression Data Browser: no data available

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊟Other Information

You are kindly invited to share additional interesting facts.