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NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS05460 [old locus tag: SA0964 ]
  • pan locus tag?: SAUPAN003342000
  • symbol: SA_RS05460
  • pan gene symbol?: ctaA
  • synonym:
  • product: heme A synthase

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SA_RS05460 [old locus tag: SA0964 ]
  • symbol: SA_RS05460
  • product: heme A synthase
  • replicon: chromosome
  • strand: -
  • coordinates: 1094834..1095904
  • length: 1071
  • essential: no DEG other strains

Accession numbers[edit | edit source]

  • Location: NC_002745 (1094834..1095904) NCBI
  • BioCyc: SA_RS05460 BioCyc
  • MicrobesOnline: see SA0964

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGTCGTCCACATACAATACTTGTAAAATTAAATCATATTTCCTGCGTTGGATCCCATCT
    TTTCATATCCTACAATCAGGTCAATTTATAGTATCATCTCAAATCCGGCTATTAATTCTA
    ATTCTCAGTGATGCGTTTTTTTATGATGGGGTGTATAAATTGTTTGGCAAAAAGAATTTA
    AAATGGTTAGGTGTCGTAGCAACGTTAATGATGACATTTGTACAACTTGGTGGAGCCTTA
    GTTACCAAAACCGGATCAGCTGATGGTTGTGGTTCTTCTTGGCCACTATGTCATGGTGCG
    TTGATTCCAGAATTCTTTCCTATTGATACGATTATTGAGTTAAGTCATAGAGCCGTTTCA
    GCTTTGTCTTTATTAATGGTCTTATGGTTAGTTATCACTGCATGGAAACATATAGGCTAT
    ATTAAAGAAATTAAACCTTTATCAATCATTAGTGTTGGATTCTTATTATTGCAAGCATTA
    ATCGGAGCTGCCGCTGTTATTTGGCAACAAAACGATTACGTTTTAGCATTGCACTTTGGT
    ATATCATTAATCAGTTTCTCATCTGTATTTTTAATAACATTGATTATTTTCTCTATAGAT
    CAAAAATATGAAGCTGACGAATTATATATCAAAAAGCCATTAAGACGTTTAACATGGTTA
    ATGGCAATCATCATTTATTGTGGTGTTTATACTGGTGCACTAGTGAGACATGCGGATGCA
    AGTTTAGCATATGGTGGTTGGCCATTGCCATTCCACGATCTTGTACCACATTCAGAACAA
    GATTGGGTTCAACTCACGCATCGTATCATGGCTTTTATAGTGTTTACGATTATTATGATT
    ACTTATATTCACGCTGTTAAAAATTATCCAAATAATCGTACTGTTCATTATGGTTATACA
    GCTGCATTTATACTTGTTATATTACAAGTTATCACAGGTGCATTATCTATTATGACAAAT
    GTTAACCTGATAATCGCACTTTTCCATGCATTATTTATCACTTATTTATTTGGTATGACA
    ACATACTTTATCATGCTAATGTTACGATCAGTAAGAAGTGACAAGCAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1071

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SA_RS05460 [old locus tag: SA0964 ]
  • symbol: SA_RS05460
  • description: heme A synthase
  • length: 356
  • theoretical pI: 9.42349
  • theoretical MW: 40263.7
  • GRAVY: 0.714888

Function[edit | edit source]

  • reaction:
    EC 1.3.-.-?  ExPASy
  • TIGRFAM:
    methanobactin biosynthesis cassette protein MbnC (TIGR04160; HMM-score: 12.7)
    surface glycoprotein signal peptide (TIGR04207; HMM-score: 11.3)
  • TheSEED: see SA0964
  • PFAM:
    2heme_cytochrom (CL0328) COX15-CtaA; Cytochrome oxidase assembly protein (PF02628; HMM-score: 115.7)
    and 2 more
    no clan defined 3-PAP; Myotubularin-associated protein (PF12578; HMM-score: 11.8)
    DUF4231; Protein of unknown function (DUF4231) (PF14015; HMM-score: 9.6)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 9
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.005647
    • TAT(Tat/SPI): 0.000259
    • LIPO(Sec/SPII): 0.003347
  • predicted transmembrane helices (TMHMM): 8

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MSSTYNTCKIKSYFLRWIPSFHILQSGQFIVSSQIRLLILILSDAFFYDGVYKLFGKKNLKWLGVVATLMMTFVQLGGALVTKTGSADGCGSSWPLCHGALIPEFFPIDTIIELSHRAVSALSLLMVLWLVITAWKHIGYIKEIKPLSIISVGFLLLQALIGAAAVIWQQNDYVLALHFGISLISFSSVFLITLIIFSIDQKYEADELYIKKPLRRLTWLMAIIIYCGVYTGALVRHADASLAYGGWPLPFHDLVPHSEQDWVQLTHRIMAFIVFTIIMITYIHAVKNYPNNRTVHYGYTAAFILVILQVITGALSIMTNVNLIIALFHALFITYLFGMTTYFIMLMLRSVRSDKQ

Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]