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NCBI: 02-MAR-2017

Summary[edit source | edit]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS06330 [old locus tag: SA1119 ]
  • pan locus tag?: SAUPAN003577000
  • symbol: SA_RS06330
  • pan gene symbol?: ftsK
  • synonym:
  • product: DNA translocase FtsK

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SA_RS06330 [old locus tag: SA1119 ]
  • symbol: SA_RS06330
  • product: DNA translocase FtsK
  • replicon: chromosome
  • strand: +
  • coordinates: 1270831..1273071
  • length: 2241
  • essential: unknown

Accession numbers[edit source | edit]

  • Location: NC_002745 (1270831..1273071) NCBI
  • MicrobesOnline:

Phenotype[edit source | edit]

Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    ATGGTGTTGGGTGTTTTCCAATTAGGAATAATCGGTCGTCTAATTGACAGCTTCTTTAAT
    TATTTATTTGGGTACAGTAGATATTTAACATATATTTTAGTACTCTTAGCAACTGGTTTT
    ATTACATACTCTAAACGTATTCCTAAAACTAGACGAACGGCTGGTTCGATTGTATTGCAA
    ATTGCATTGCTATTTGTATCACAGTTAGTTTTTCATTTTAATAGTGGTATCAAAGCTGAA
    AGAGAACCTGTACTTTCTTATGTATATCAGTCATACCAACACAGTCATTTTCCAAATTTT
    GGTGGCGGTGTATTAGGTTTTTATTTATTAGAGTTAAGCGTACCTTTAATTTCATTATTT
    GGTGTATGTATTATTACTATTTTATTATTATGCTCAAGTGTTATTTTATTAACAAACCAT
    CAACATCGTGATGTTGCAAAAGTTGCACTGGAAAATATAAAAGCTTGGTTTGGTTCATTT
    AATGAAAAAATGTCGGAAAGAAACCAAGAAAAACAATTGAAGCGTGAAGAAAAAGCGAGA
    CTTAAAGAAGAACAAAAGGCACGTCAAAATGAACAGCCACAAATAAAAGATGTGAGTGAT
    TTTACGGAAGTGCCTCAAGAAAGAGATATTCCAATTTATGGGCATACTGAAAATGAAAGT
    AAAAGCCAGTGTCAACCAAGTCGAAAAAAACGAGTGTTTGATGCAGAGAATAGTTCGAAT
    AACATCGTAAATCATCAAGCAGATCAGCAAGAGCAATTAACAGAACAAACTCATAACAGT
    GTTGAAAGTGAAAACACTATTGAAGAAGCTGGTGAAGTTACGAATGTATCGTATGTTGTT
    CCACCGTTAACTTTACTTAATCAACCTGCAAAACAAAAAGCAACATCTAAAGCTGAAGTA
    CAACGTAAAGGACAAGTACTAGAGAATACATTAAAAGATTTTGGGGTAAATGCAAAAGTG
    ACACAAATTAAAATTGGTCCTGCAGTAACTCAATATGAAATTCAACCAGCTCAAGGGGTT
    AAAGTGAGTAAAATTGTAAACTTGCATAATGATATTGCATTAGCTTTAGCAGCAAAAGAT
    GTTAGAATCGAAGCACCAATACCTGGTCGCTCTGCAGTAGGTATTGAAGTGCCAAATGAG
    AAAATTTCATTAGTTTCACTAAAAGAAGTTTTAGATGAAAAATTCCCGTCTAATAATAAA
    CTAGAAGTTGGATTAGGAAGAGATATATCAGGTGATCCAATTACTGTTCCACTAAATGAA
    ATGCCACACTTATTGGTGGCAGGATCGACGGGTAGTGGTAAATCTGTTTGTATAAATGGT
    ATTATTACAAGTATTTTATTAAATGCTAAGCCGCATGAAGTTAAACTTATGTTAATCGAT
    CCGAAAATGGTTGAACTAAATGTTTATAACGGAATTCCACATTTATTAATTCCGGTTGTT
    ACAAATCCTCATAAAGCTGCTCAAGCTTTAGAAAAAATTGTAGCTGAGATGGAAAGACGT
    TATGATTTATTCCAACATTCATCAACTAGAAATATTAAAGGTTATAACGAATTAATCCGT
    AAGCAAAATCAAGAATTAGATGAGAAGCAACCAGAATTACCTTATATCGTTGTTATTGTA
    GATGAGCTTGCAGATTTAATGATGGTAGCTGGTAAAGAAGTTGAAAATGCGATTCAACGT
    ATCACACAAATGGCACGTGCAGCAGGTATACATTTGATTGTAGCAACACAAAGACCTTCT
    GTGGATGTAATTACAGGTATCATTAAAAATAACATTCCATCTAGAATTGCTTTTGCTGTG
    AGTTCTCAAACAGATTCAAGAACTATTATTGGTACTGGCGGTGCAGAAAAGTTACTTGGT
    AAAGGTGACATGTTATACGTTGGAAATGGTGATTCATCACAAACACGTATTCAAGGGGCG
    TTTTTAAGTGACCAAGAGGTGCAAGATGTTGTAAATTATGTAGTAGAACAACAACAGGCA
    AATTATGTAAAAGAAATGGAACCAGATGCACCAGTGGATAAATCGGAAATGAAAAGTGAA
    GATGCTTTATATGATGAAGCGTATTTGTTTGTTGTTGAACAACAAAAGGCAAGTACATCA
    TTGTTACAACGCCAATTTAGAATTGGTTATAATAGAGCATCTAGGTTGATGGATGATTTA
    GAACGCAATCAGGTAATCGGTCCACAAAAAGGAAGCAAGCCTAGACAAGTTTTAATAGAT
    CTTAATAATGACGAGGTGTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1740
    1800
    1860
    1920
    1980
    2040
    2100
    2160
    2220
    2241

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SA_RS06330 [old locus tag: SA1119 ]
  • symbol: SA_RS06330
  • description: DNA translocase FtsK
  • length: 746
  • theoretical pI: 6.58004
  • theoretical MW: 83269.7
  • GRAVY: -0.256032

Function[edit source | edit]

  • TIGRFAM:
    Genetic information processingProtein fateProtein and peptide secretion and traffickingtype VII secretion protein EssC (TIGR03928; HMM-score: 124.1)
    Genetic information processingProtein fateProtein and peptide secretion and traffickingtype VII secretion protein EccCa (TIGR03924; HMM-score: 103.2)
    and 4 more
    Genetic information processingProtein fateProtein and peptide secretion and traffickingtype VII secretion protein EccCb (TIGR03925; HMM-score: 65.2)
    Genetic information processingMobile and extrachromosomal element functionsOtherconjugative coupling factor TraD, SXT/TOL subfamily (TIGR03743; HMM-score: 15.4)
    type IV conjugative transfer system coupling protein TraD (TIGR02759; HMM-score: 12.4)
    MetabolismTransport and binding proteinsCations and iron carrying compoundscation transporter family protein (TIGR00860; HMM-score: 11.6)
  • TheSEED:
  • PFAM:
    P-loop_NTPase (CL0023) FtsK_SpoIIIE; FtsK/SpoIIIE family (PF01580; HMM-score: 205.7)
    and 14 more
    HTH (CL0123) Ftsk_gamma; Ftsk gamma domain (PF09397; HMM-score: 100.7)
    P-loop_NTPase (CL0023) AAA_10; AAA-like domain (PF12846; HMM-score: 26.6)
    no clan definedFtsK_4TM; 4TM region of DNA translocase FtsK/SpoIIIE (PF13491; HMM-score: 21.2)
    P-loop_NTPase (CL0023) AAA_19; AAA domain (PF13245; HMM-score: 20.8)
    DUF87; Domain of unknown function DUF87 (PF01935; HMM-score: 20.5)
    ClpP_crotonase (CL0127) Peptidase_S49_N; Peptidase family S49 N-terminal (PF08496; HMM-score: 17.5)
    P-loop_NTPase (CL0023) AAA_22; AAA domain (PF13401; HMM-score: 16.9)
    T2SSE; Type II/IV secretion system protein (PF00437; HMM-score: 15.6)
    TrwB_AAD_bind; Type IV secretion-system coupling protein DNA-binding domain (PF10412; HMM-score: 14.9)
    AAA; ATPase family associated with various cellular activities (AAA) (PF00004; HMM-score: 14.2)
    no clan definedNeur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region (PF02932; HMM-score: 14.1)
    P-loop_NTPase (CL0023) AAA_29; P-loop containing region of AAA domain (PF13555; HMM-score: 13.5)
    no clan definedCodanin-1_C; Codanin-1 C-terminus (PF15296; HMM-score: 11)
    Peptidase_AD (CL0130) Presenilin; Presenilin (PF01080; HMM-score: 6.4)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 3
  • LocateP:
  • SignalP: no predicted signal peptide
    • Ymax: 0.11
    • Ymax_pos: 68
    • Cmax: 0.172
    • Cmax_pos: 47
    • Smax: 0.165
    • Smax_pos: 55
    • Smean: 0.062
    • D: 0.091
  • predicted transmembrane helices (TMHMM): 4

Accession numbers[edit source | edit]

  • GI:
  • RefSeq: WP_001811366 NCBI
  • UniProt:

Protein sequence[edit source | edit]

  • MVLGVFQLGIIGRLIDSFFNYLFGYSRYLTYILVLLATGFITYSKRIPKTRRTAGSIVLQIALLFVSQLVFHFNSGIKAEREPVLSYVYQSYQHSHFPNFGGGVLGFYLLELSVPLISLFGVCIITILLLCSSVILLTNHQHRDVAKVALENIKAWFGSFNEKMSERNQEKQLKREEKARLKEEQKARQNEQPQIKDVSDFTEVPQERDIPIYGHTENESKSQCQPSRKKRVFDAENSSNNIVNHQADQQEQLTEQTHNSVESENTIEEAGEVTNVSYVVPPLTLLNQPAKQKATSKAEVQRKGQVLENTLKDFGVNAKVTQIKIGPAVTQYEIQPAQGVKVSKIVNLHNDIALALAAKDVRIEAPIPGRSAVGIEVPNEKISLVSLKEVLDEKFPSNNKLEVGLGRDISGDPITVPLNEMPHLLVAGSTGSGKSVCINGIITSILLNAKPHEVKLMLIDPKMVELNVYNGIPHLLIPVVTNPHKAAQALEKIVAEMERRYDLFQHSSTRNIKGYNELIRKQNQELDEKQPELPYIVVIVDELADLMMVAGKEVENAIQRITQMARAAGIHLIVATQRPSVDVITGIIKNNIPSRIAFAVSSQTDSRTIIGTGGAEKLLGKGDMLYVGNGDSSQTRIQGAFLSDQEVQDVVNYVVEQQQANYVKEMEPDAPVDKSEMKSEDALYDEAYLFVVEQQKASTSLLQRQFRIGYNRASRLMDDLERNQVIGPQKGSKPRQVLIDLNNDEV

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • SA_RS06330 no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]