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FunGene: 08-OCT-2024

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_002167
  • pan locus tag?: SAUPAN005595000
  • symbol: JSNZ_002167
  • pan gene symbol?: cobB
  • synonym:
  • product: NAD-dependent protein deacylase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_002167
  • symbol: JSNZ_002167
  • product: NAD-dependent protein deacylase
  • replicon: chromosome
  • strand: +
  • coordinates: 2185178..2185918
  • length: 741
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    GTGTTTATTTTGAGAAATGATTTAGAGACATTAAAACATATTATAGATAGTTCGAATCGT
    ATTACATTTTTCACAGGTGCTGGTGTATCTGTCGCAAGTGGCGTTCCAGATTTCCGTTCA
    ATGGGTGGCTTATTTGATGAAATTTCAAAAGATGGACTTTCGCCAGAATACTTGTTAAGC
    CGTGATTATTTAGAAGATGATCCTGAAGGTTTTATCAATTTCTGCCATAAGCGTTTACTA
    TTTGTCGATACGAAGCCTAATATCGTTCATGATTGGATTGCAAAATTAGAACGTAATCAA
    CAATCTTTAGGTGTCATCACGCAAAATATCGATGGTTTGCACTCAGACGCTGGAAGTCAA
    CATGTTGATGAATTACATGGCACGTTAAATCGTTTTTATTGTAATGCATGTCATAAATCT
    TATACGAAGTCAGATGTTATTGATAGAACTTTGAAACATTGTGATAATTGTGGTGGTGCC
    ATTCGACCGGACATCGTATTATACGGTGAAATGTTAGATCAACCTACCATCATAAGGGCA
    TTAAATAAAATTGAACATGCTGACACCCTTGTTGTACTAGGTTCATCACTCGTTGTACAA
    CCTGCCGCAGGATTAATATCACATTTTAAAGGCGACAATTTAATTATTATCAATAAAGAT
    CGAACACCTTATGATAGCGACGCTACTTTGGTCATACATGACGACATGGTTTCCGTTGTA
    AAATCATTAATGACAGAGTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    741

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: JSNZ_002167
  • symbol: JSNZ_002167
  • description: NAD-dependent protein deacylase
  • length: 246
  • theoretical pI: 5.28239
  • theoretical MW: 27398.9
  • GRAVY: -0.142683

⊟Function[edit | edit source]

  • reaction:
    EC 2.3.1.286?  ExPASy
    non-specified enzyme name
  • TIGRFAM:
    Signal transduction Regulatory functions DNA interactions putative regulatory protein, FmdB family (TIGR02605; HMM-score: 11.8)
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    NADP_Rossmann (CL0063) SIR2; Sir2 family (PF02146; HMM-score: 199.3)
    and 4 more
    Multiheme_cytos (CL0317) Cytochrome_C7; Cytochrome c7 and related cytochrome c (PF14522; HMM-score: 12.7)
    Zn_Beta_Ribbon (CL0167) Zn_ribbon_Nudix; Nudix N-terminal (PF14803; HMM-score: 12.5)
    Ribosomal_S27; Ribosomal protein S27a (PF01599; HMM-score: 10.3)
    Zn_ribbon_TFIIB; Transcription factor zinc-finger (PF13453; HMM-score: 9.8)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9968
    • Cytoplasmic Membrane Score: 0.0011
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0021
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.045364
    • TAT(Tat/SPI): 0.061573
    • LIPO(Sec/SPII): 0.010598
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MFILRNDLETLKHIIDSSNRITFFTGAGVSVASGVPDFRSMGGLFDEISKDGLSPEYLLSRDYLEDDPEGFINFCHKRLLFVDTKPNIVHDWIAKLERNQQSLGVITQNIDGLHSDAGSQHVDELHGTLNRFYCNACHKSYTKSDVIDRTLKHCDNCGGAIRPDIVLYGEMLDQPTIIRALNKIEHADTLVVLGSSLVVQPAAGLISHFKGDNLIIINKDRTPYDSDATLVIHDDMVSVVKSLMTE

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Blanca Taboada, Karel Estrada, Ricardo Ciria, Enrique Merino
    Operon-mapper: a web server for precise operon identification in bacterial and archaeal genomes.
    Bioinformatics: 2018, 34(23);4118-4120
    [PubMed:29931111] [WorldCat.org] [DOI] (I p)

⊟Relevant publications[edit | edit source]

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