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NCBI: 26-AUG-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA2276
  • pan locus tag?: SAUPAN006083000
  • symbol: SA2276
  • pan gene symbol?: —
  • synonym:
  • product: hypothetical protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SA2276
  • symbol: SA2276
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 2551608..2553098
  • length: 1491
  • essential: no DEG other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    GTGAGTAGCAAAAAAGAAGCTTATGATTTAGCGGATAAACTAAGTTCAAAAGGGATTAAA
    AGTGTTGCTTTAACAGGAGATGATAGTGTTAATTATCGCCAAATTGTAATAGAAAAATTA
    AAAGAAGGTAAGATTAACTATATTATAACTGTAGATCTTTTTAACGAAGGTATTGATATT
    CCAGAAGTCAATCAAGTTGTAATGTTGAGACCAACAGAGTCTAGTATTATATTCATTCAG
    CAACTTGGTAGAGGATTAAGAAAAAGTGCAAATAAAGAGTATGTTACTGTAATTGATTTT
    ATTGGTAATTATAAGACCAATTATTTAATTCCGATTGCGCTTTCTGGGGATCAATCGCAA
    AATAAAGATAATTATAAGAAGTTTTTAACGAATAACGATTCGATTAATGGAGTATCTACA
    ATTAATTTTGAAGAAGTTGCTAAAAAACAGATTTACAATTCATTGGATGCAGTATCATTG
    AATCAAAATAAATTAATATTAAAAGCTTATGAAGAAGTTGAAAATAGATTGGGACACATG
    CCGTTACTAATGGATTTTATACAACAACATTCTATAGATCCAAGCGTTATATTTTCTAAA
    TTTAGTAATTATTACGAATTTTTATTAAGGTATAAAAAAATAGATGCTTTATTGACGGAA
    AATGAATCTAAAAATCTGGTTTTCTTTTCAAGACAAATAGCACCTGGATTGAAAAGAATC
    GATAGTTTAGTTTTAGAAGAACTTTTAAAAAATGAATTAACATATGATGAATTAAAAAAT
    AAAATGTTGAACGAAGTTAAGGATATAACAGAAGATGATATAGATACTTCATTAAGAATT
    TTAGATTTTTCATTTTACAACGCAGGAATTGAAAAAATCTATGGAAGTCCCATTATAGAA
    TGTAATGAAAGAATGATAAGACTAAGCGATGCATTTACTAATGCTCTAAGTAATCAAACA
    TTTAAAATATTTTTAGAAGATCTTATTGAATTATCAAAGTATAACAATGAAAAATACCAA
    AAAGGTAAAAATGGACTGATTTTATATAATAAATATTCAAGAGAAGATTTTAGCAAAATA
    TTTAATTGGAATAAAAATGGTTCGTCTGTAATCATGGGATACATGATAAGAAGCCAAGAA
    ATGCCAATATTTATCACTTATGATAAGCATGAGGATATAAGTGATAGTACAAAATATGAA
    GATGAATTTTTAAGTCAAGATGAATTAAAATGGTTTACTAAATCTAATAGAACGCTAAAA
    TCAAAAGAAGTTCAGAAAATTTTGTCCCATAGAGCAAAAGGAATTAAAATGTATATTTTT
    GTACAGAAAAAAGATGATGATGGTATATATTTTTATTATTTAGGAACTGCTGGATATATA
    GAAGGTTCAGAGAAGCAAGATAAAATGCCGAATGGTTCAAACGTAGTAACGATGGATTTA
    GCACTCGATAAAGCTGTAAGAGATGATATATATCGCTATATAACAAATTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1491

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SA2276
  • symbol: SA2276
  • description: hypothetical protein
  • length: 496
  • theoretical pI: 5.48834
  • theoretical MW: 57476.1
  • GRAVY: -0.463105

⊟Function[edit | edit source]

  • TIGRFAM:
    DNA phosphorothioation system restriction enzyme (TIGR04095; HMM-score: 43.6)
    and 4 more
    Genetic information processing DNA metabolism DNA replication, recombination, and repair excinuclease ABC subunit B (TIGR00631; EC 3.1.25.-; HMM-score: 31.9)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair ATP-dependent DNA helicase, RecQ family (TIGR00614; EC 3.6.4.12; HMM-score: 16.5)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair ATP-dependent DNA helicase RecQ (TIGR01389; EC 3.6.4.12; HMM-score: 14.5)
    DEXH box helicase, DNA ligase-associated (TIGR04121; EC 3.6.4.-; HMM-score: 13.4)
  • TheSEED  :
    • DNA/RNA helicase of DEAD/DEAH box family
  • PFAM:
    no clan defined DUF3427; Domain of unknown function (DUF3427) (PF11907; HMM-score: 267.9)
    and 3 more
    P-loop_NTPase (CL0023) Helicase_C; Helicase conserved C-terminal domain (PF00271; HMM-score: 56)
    no clan defined Corona_nucleoca; Coronavirus nucleocapsid protein (PF00937; HMM-score: 11.7)
    DUF1735 (CL0594) DUF4973; Domain of unknown function (DUF4973) (PF16343; HMM-score: 11.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.004895
    • TAT(Tat/SPI): 0.00027
    • LIPO(Sec/SPII): 0.00096
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MSSKKEAYDLADKLSSKGIKSVALTGDDSVNYRQIVIEKLKEGKINYIITVDLFNEGIDIPEVNQVVMLRPTESSIIFIQQLGRGLRKSANKEYVTVIDFIGNYKTNYLIPIALSGDQSQNKDNYKKFLTNNDSINGVSTINFEEVAKKQIYNSLDAVSLNQNKLILKAYEEVENRLGHMPLLMDFIQQHSIDPSVIFSKFSNYYEFLLRYKKIDALLTENESKNLVFFSRQIAPGLKRIDSLVLEELLKNELTYDELKNKMLNEVKDITEDDIDTSLRILDFSFYNAGIEKIYGSPIIECNERMIRLSDAFTNALSNQTFKIFLEDLIELSKYNNEKYQKGKNGLILYNKYSREDFSKIFNWNKNGSSVIMGYMIRSQEMPIFITYDKHEDISDSTKYEDEFLSQDELKWFTKSNRTLKSKEVQKILSHRAKGIKMYIFVQKKDDDGIYFYYLGTAGYIEGSEKQDKMPNGSNVVTMDLALDKAVRDDIYRYITN

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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