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NCBI: 10-JUN-2013
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus COL
- locus tag: SACOL1877 [new locus tag: SACOL_RS09630 ]
- pan locus tag?: SAUPAN004584000
- symbol: epiB
- pan gene symbol?: epiB
- synonym:
- product: epidermin biosynthesis protein EpiB
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SACOL1877 [new locus tag: SACOL_RS09630 ]
- symbol: epiB
- product: epidermin biosynthesis protein EpiB
- replicon: chromosome
- strand: -
- coordinates: 1928827..1931820
- length: 2994
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
- Gene ID: 3237151 NCBI
- RefSeq: YP_186704 NCBI
- BioCyc: see SACOL_RS09630
- MicrobesOnline: 913319 MicrobesOnline
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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2941ATGAACACTATTTACGAACCGTCAAGTATTTGTATGATTAGAACACCTTTATTATCAGTT
GAATTTTTCAATTTATTTTTAAATACTGAACAAATTAAATATAGCGACTTACAATTAAAT
GCTCAGATGAAAGAATCAATCCTAACAACAACATTTAACTTATATTGTACTTTACAAGAA
ATAAATTTTGATGGCGATAACAAGAAGGTTAGAGATGCTAAAGAAAGTTTATTAAAATAT
TTAATTAGAATGTCAACACGTCCAACTCCATTTGGATTATTAAGTGGTATTAATTTGGGG
CATTTTGTAAATGAACCAACACGTCTTAAAGTTGGAAATAGTATTCAAAAATATGTGAAA
GTCGATGGCGAATGGTTGTATAAACTGGTTAGTTATATTGAGAGTATTGATGAATATTAT
CAAAATTTGAAAGTTATTTGGAATAGTAAAGCACATATTATCAATGATCGAATATATTTA
AATGAACAAAGTGCTATTTATTTAAACAACAATAAAGATACATCTTTTTCCATTAAAAAT
AGCGAATTACTCGTATTCATCAAAACCACTGTGACGAATAATAATATTACTTTTTCAAAT
TTAGCTGAAAAGATAAATCAAGAATTTGAAATTAATGATATTACTAAAGTGAAAGTATAT
ATCCATAATCTTGTCTCAAAGGAAATTATATATTCAACAATCAGACCACCGTTATCATAT
AGCGATAATTTAAATTATATTTTAAATAAACTTTCTTTACATAATGATGATTTTGTGAAA
AAAATTAGAGAAATCCAGAAATTGATATTAGCTTATGAAAAAACTGAAATTGGATTTGGC
GAGGAATTATATAAAGACATTATTCATCATATGAAGGCACTATTCAAATGTAAAAACTAT
CTTCAAATTGATACCAAAATTGACATGATTAACAATTATTTACATCAAGATATAGCAACA
AATATATCTGAAGCAGCGTACTTATTGTGGCTTTTATCAAGAAATAATATTGGATTCACA
GATTTGAAAGTTCTTCACAACCGTTTTATTGAAAAGTATGGATTTGAACAACTCGTGAAT
ATTAAAGATTTGATTTCAGATATAACAGGTTTCGGGACAACAATTTTTCAAGAAGAAGAA
ACCGATGGAAATAATATTGTAATGCTTAAGCAAAAATTTTTACATGCCTTGAGAAATAAC
GATGAGATAGTCATAAATGAAAAAGATGTAGAGTCATTGATTAACGATAATGAAATCAAT
CATTATCATGCGCCAATGAGTGCAGATGTTTATGCTGAACTTTATTTAGGACGTTTTTAC
AATCAGTACAATGAGCTCATTGTTATTAGTCCTTTAACGGCGTCTTTTAATGCTGGCGCT
ACATTTGGGCGATTTCATCATTTAATTGATACTGAAACTTTAGCAAAATTAGAACATGAA
AAAGGACATTATTATCAGAAGATGATATGTGATGACAATGTAGAAATGATTTCTATAAAT
AACATACCGAAATATCCGAGAAATCATAATGTATTAACTAATCATGACTCATACGAATAT
TCATTGAATTTAGGAAGTAGTAATAGTTATTCAAAGTATGAGCTTACCTTAGATGATATT
TATGTTGGTGCTACCTTTAACAAATTATATTTATATTCTAGCCAACTAAATAAAAGGGTA
ATATTTGAATCAAACAATATGTATAACTTTTTAAAAGAATGTAATTTATATCGATTGTTA
CGAGAAATTTCAATGGAATCTGTGAAATGCATTGAACCTATGAATGATGTGAGTATTGAT
TCATTTAGTTATTCACCACGAATCAGATATAAAAATGTCATTCTTAAACCAGCATATTGG
AAAATTAACGAGATGGTATTACCTTTACCTAAAAATGAAGAATGGGATCAACAATTTTTG
AAATATCAAGAACAATTCAATATACCTAATATCGTGAATTTAGTTTATGGAGATAACAAG
CTTCTACTAAATTTATCATTAGCTAATCATAGATATTTATTGATGAAAGAATATAAGAAG
CATAAACGTGTACGTTTAGTAGAATCATTTTTACCTCAATCAAAGAATGATCATGTGTAT
GAAATTGTTACACCAATTTATAAAAAATCATCTTATCGAGGACCCGAAATCGAAATTCCA
AAATATAAAAATACAGATATTGAATATGACAAAGACTGGTTTGCATTACATATTCATATC
GATAAGCCATCGCAAGATACATTTATCATCGACAATTTGTATCCATTTGTAAAACATCTT
AAAGATAAGGGAGATATAGATCAATATTTTTTAATGCGTTATATCAAACAAGGTGACATT
TTAAAGTTGAGGTTATTCAGGAATGACGAAAATTACGCAGAAATATACAGCATCTTGAAG
AATTGGTTACCACATGTTCGACAAACGACAGAAGTTTCAGATTATGAATTTGTATCATAC
GAGCCAGAATTTTTTAGATATGGTGGAAAGAACACGATTAATGAAATAGAAGCCTTCTTT
GAATATGACACGAATTTAGCTGTCAATATTATTGAAAATGATTTTAAGTTTGATCGACCA
TATATTGTTGCTATTTCAATAATGTATTTATTTGAGATGTTTTCAATTTCTAATGAAGAG
CGTATGGAAATTGTTAATAACTATGTACCTACATCATTTAAAAGTAAAGATATTAGACCT
TTTAAAAATGAACTTGTAACTATATGTAATCCTGCTAATAATTTTGAATATATGGCTAAA
CACTATAGTGGTATTTATCGAATTTTAAAAGATGGCAACCAAATTTTGAGCAAATTAAAT
GAAGGGCTTAAAAAAACTTTAACTACTAAAAGGTCAAGGATTATTGGCAGCTTAATTCAT
ATGCGCTGCAATCGAATATTTGGCATTGATAAGGATCAAGAAACATTTGTTTTATCTATT
GTAAAAGAAATTGTTAAAACTCAAAAGCATTGGTGTGGTGACAAAAATGATTGA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SACOL1877 [new locus tag: SACOL_RS09630 ]
- symbol: EpiB
- description: epidermin biosynthesis protein EpiB
- length: 997
- theoretical pI: 6.73397
- theoretical MW: 117635
- GRAVY: -0.404514
⊟Function[edit | edit source]
- TIGRFAM: Cellular processes Toxin production and resistance thiopeptide-type bacteriocin biosynthesis domain (TIGR03891; HMM-score: 204.6)
- TheSEED :
- Lanthionine biosynthesis protein LanB
- PFAM: no clan defined Lant_dehydr_N; Lantibiotic dehydratase, C terminus (PF04738; HMM-score: 505.2)and 1 moreLant_dehydr_C; Lantibiotic biosynthesis dehydratase C-term (PF14028; HMM-score: 85)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic Membrane
- Cytoplasmic Score: 1.05
- Cytoplasmic Membrane Score: 8.78
- Cellwall Score: 0.08
- Extracellular Score: 0.09
- Internal Helices: 0
- LocateP: Intracellular
- Prediction by SwissProt Classification: Cytoplasmic
- Pathway Prediction: No pathway
- Intracellular possibility: 1
- Signal peptide possibility: -1
- N-terminally Anchored Score: 1
- Predicted Cleavage Site: No CleavageSite
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.015967
- TAT(Tat/SPI): 0.000255
- LIPO(Sec/SPII): 0.002157
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MNTIYEPSSICMIRTPLLSVEFFNLFLNTEQIKYSDLQLNAQMKESILTTTFNLYCTLQEINFDGDNKKVRDAKESLLKYLIRMSTRPTPFGLLSGINLGHFVNEPTRLKVGNSIQKYVKVDGEWLYKLVSYIESIDEYYQNLKVIWNSKAHIINDRIYLNEQSAIYLNNNKDTSFSIKNSELLVFIKTTVTNNNITFSNLAEKINQEFEINDITKVKVYIHNLVSKEIIYSTIRPPLSYSDNLNYILNKLSLHNDDFVKKIREIQKLILAYEKTEIGFGEELYKDIIHHMKALFKCKNYLQIDTKIDMINNYLHQDIATNISEAAYLLWLLSRNNIGFTDLKVLHNRFIEKYGFEQLVNIKDLISDITGFGTTIFQEEETDGNNIVMLKQKFLHALRNNDEIVINEKDVESLINDNEINHYHAPMSADVYAELYLGRFYNQYNELIVISPLTASFNAGATFGRFHHLIDTETLAKLEHEKGHYYQKMICDDNVEMISINNIPKYPRNHNVLTNHDSYEYSLNLGSSNSYSKYELTLDDIYVGATFNKLYLYSSQLNKRVIFESNNMYNFLKECNLYRLLREISMESVKCIEPMNDVSIDSFSYSPRIRYKNVILKPAYWKINEMVLPLPKNEEWDQQFLKYQEQFNIPNIVNLVYGDNKLLLNLSLANHRYLLMKEYKKHKRVRLVESFLPQSKNDHVYEIVTPIYKKSSYRGPEIEIPKYKNTDIEYDKDWFALHIHIDKPSQDTFIIDNLYPFVKHLKDKGDIDQYFLMRYIKQGDILKLRLFRNDENYAEIYSILKNWLPHVRQTTEVSDYEFVSYEPEFFRYGGKNTINEIEAFFEYDTNLAVNIIENDFKFDRPYIVAISIMYLFEMFSISNEERMEIVNNYVPTSFKSKDIRPFKNELVTICNPANNFEYMAKHYSGIYRILKDGNQILSKLNEGLKKTLTTKRSRIIGSLIHMRCNRIFGIDKDQETFVLSIVKEIVKTQKHWCGDKND
⊟Experimental data[edit | edit source]
- experimentally validated:
- protein localization: Cytoplasmic [1]
- quantitative data / protein copy number per cell:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You are kindly invited to share additional interesting facts.
⊟Literature[edit | edit source]
⊟References[edit | edit source]
- ↑ Andreas Otto, Jan Maarten van Dijl, Michael Hecker, Dörte Becher
The Staphylococcus aureus proteome.
Int J Med Microbiol: 2014, 304(2);110-20
[PubMed:24439828] [WorldCat.org] [DOI] (I p)