PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

⊟Summary

• pan ID^?: SAUPAN006071000
• symbol^?: —
• synonym:
• description^?: Insertion sequenceATP-binding protein

  descriptions from strain specific annotations:

  • Insertion sequenceATP-binding protein
  • Insertion sequenceATP-binding protein, putative
  • membrane protein
  • pseudogene
• strand^?: -
• coordinates^?: 6116259..6117533
• synteny block^?: BlockID0048120
• occurrence^?: in 67% of 33 strains

Suggest new symbol of "tslB_ψ" and description of "Type VII-secreted phospholipase toxin TslB, pseudogene" to harmonize with PMID 38114483. Please note that some strains will not have the frameshift that makes this a pseudogene.

⊟Orthologs

COL:
SACOL2496
N315:
SA2272
NCTC8325:
SAOUHSC_02786
Newman:
NWMN_2383
USA300_FPR3757:
SAUSA300_2427
04-02981:
SA2981_2421
08BA02176:
C248_2542
11819-97:
—
6850:
RSAU_002323
71193:
ST398NM01_2541
ECT-R 2:
ECTR2_2341
ED133:
SAOV_2531c
ED98:
SAAV_2550
HO 5096 0412:
SAEMRSA15_23840
JH1:
SaurJH1_2563
JH9:
SaurJH9_2511
JKD6008:
—
JKD6159:
SAA6159_02380
LGA251:
—
M013:
M013TW_2445
MRSA252:
—
MSHR1132:
—
MSSA476:
—
Mu3:
SAHV_2468
Mu50:
SAV2484
MW2:
—
RF122:
SAB2367c
ST398:
SAPIG2541
T0131:
—
TCH60:
—
TW20:
—
USA300_TCH1516:
USA300HOU_2476
VC40:
—

⊟Genome Viewer

COL
N315
NCTC8325
Newman
USA300_FPR3757

⊟Alignments

• alignment of orthologues:
  CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
  
  
  COL             MSQTEYQIKSGNIKGNSEETSTVSNISYEIENANNSGLKQNKIDKQIKKLQEKNKFPKNL
  N315            MNKTKYQINSDNIKSNSEETSAISSISYEIENANNNDLNNASIQTQIEILKSQNSFPKNL
  Newman          MSQTEYQIKSGNIKGNSEETSTVSNISYEIENANNSGLKQNKIDKQIKKLQEKNKFPKNL
                  *.:*:***:*.***.******::*.**********..*:: .*:.**: *:.:*.*****
  
  COL             SYLKSYTDPKTGTTTSAFLNKDTGKVTLGMTGTNVHKDAILKQTFGVPSYQGYIDVSETL
  N315            SYLKSYTDPKTGTTTSAFLNKDTGKVTLGMTGTNVHKDAILKQTFGVPSYQGYIDASETL
  Newman          SYLKSYTDPKTGTTTSAFLNKDTGKVTLGMTGTNVHKDAILKQTFGVPSYQGYIDVSETL
                  *******************************************************.****
  
  COL             KDIGADVNIGLHSVTDKDPHYKNTQDFIKNIKKDYDIDIITGHSLGGRDAMILGMSNDIK
  N315            KDIGADVNIGLHSVTDKDPHYKNTQDFIKNIKKDYDIDIITGHSLGGRDAMILGMSNDIK
  Newman          KDIGADVNIGLHSVTDKDPHYKNTQDFIKNIKKDYDIDIITGHSLGGRDAMILGMSNDIK
                  ************************************************************
  
  COL             HIVVYNPAPLAIKDVSGLYADQEELKKLIEKYDGHIVRFVSDEDELDAGVRNHLYETAGE
  N315            HIVVYNPAPLAIKDVSGLYADQEELKKLIEKYDGHIVRFVSDEDELDAGVRNHLYETAGE
  Newman          HIVVYNPAPLAIKDVSGLYADQEELKKLIEKYDGHIVRFVSDEDELDAGVRNHLYETAGE
                  ************************************************************
  
  COL             KIVLKNGEGHAMSGILMSRTQAIILAELNKVKGYQDENNKALKSVRKQTRHRLHKVETLR
  N315            KIVLKNGEGHAMSGILMSRTQAIILAELNKVKGYQDENNKALKSVRKQTRHRLHKVETLR
  Newman          KIVLKNGEGHAMSGILMSRTQAIILAELNKVKGYQDENNKALKSVRKQTRHRLHKVETLR
                  ************************************************************
  
  COL             ANWIQTTGGSLSSSQQQLLEALTALTIAEGLNQLVNEESQHLKKCITRWHINLETTGKKR
  N315            ANWIQTTGGSLSSSQQQLLEALTALTIAEGLNQLVNEESQHLKK---MYHAMAHKFGDNW
  Newman          ANWIQTTGGSLSSSQQQLLEALTALTIAEGLNQLVNEESQHLKKCITRWHINLETTGKKR
                  ********************************************    :*   .. *.: 
  
  COL             KKLE--------------------------------------------------------
  N315            KKAQEVGNEIGEKLTSEEVIDELRKGGAYESKLETDPKRKIDDKIKKLNDVYKNCNGYIA
  Newman          KKLE--------------------------------------------------------
                  ** :                                                        
  
  COL             ------MKLVKN------------
  N315            KIKQSIEAIVSNDQMLASQIDGMM
  Newman          ------MKLVKN------------
                          :*.*