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NCBI: 10-JUN-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus USA300_FPR3757
  • locus tag: SAUSA300_2216 [new locus tag: SAUSA300_RS12230 ]
  • pan locus tag?: SAUPAN005722000
  • symbol: SAUSA300_2216
  • pan gene symbol?: —
  • synonym:
  • product: MarR family transcriptional regulator

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SAUSA300_2216 [new locus tag: SAUSA300_RS12230 ]
  • symbol: SAUSA300_2216
  • product: MarR family transcriptional regulator
  • replicon: chromosome
  • strand: +
  • coordinates: 2386471..2386911
  • length: 441
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    ATGCTATCACAAGAATTTTTCAATAGTTTTATAACAATATATCGCCCCTATTTAAAATTA
    GCCGAGCCGATTTTAGAAAAACACAATATATATTATGGCCAATGGTTAATCTTACGCGAT
    ATCGCTAAACATCAGCCCACTACTCTCATTGAAATTTCACATAGACGTGCAATTGAAAAG
    CCTACTGCAAGAAAAACTTTAAAAGCTCTAATAGAAAATGACCTTATAACAGTAGAAAAC
    AGTTTAGAGGATAAACGACAAAAGTTTTTAACTTTAACACCTAAAGGGCATGAATTATAT
    GAGATTGTTTGTCTTGATGTACAAAAGCTCCAACAAGCAGTAGTTGCCAAAACAAACATT
    TCGCAAGATCAAATGCAAGAAACCATAAATGTGATGAATCAAATTCATGAAATATTATTA
    AGGGAGGCACACAATGACTAA
    60
    120
    180
    240
    300
    360
    420
    441

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SAUSA300_2216 [new locus tag: SAUSA300_RS12230 ]
  • symbol: SAUSA300_2216
  • description: MarR family transcriptional regulator
  • length: 146
  • theoretical pI: 7.16214
  • theoretical MW: 17179.8
  • GRAVY: -0.372603

⊟Function[edit | edit source]

  • TIGRFAM:
    homoprotocatechuate degradation operon regulator, HpaR (TIGR02337; HMM-score: 50.4)
    and 4 more
    Signal transduction Regulatory functions DNA interactions staphylococcal accessory regulator family (TIGR01889; HMM-score: 17)
    EPS-associated transcriptional regulator, MarR family (TIGR04176; HMM-score: 13.1)
    Signal transduction Regulatory functions DNA interactions beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family (TIGR02431; HMM-score: 12.7)
    putative choline sulfate-utilization transcription factor (TIGR03418; HMM-score: 12.2)
  • TheSEED  :
    • Transcriptional regulator, MarR family
  • PFAM:
    HTH (CL0123) HTH_27; Winged helix DNA-binding domain (PF13463; HMM-score: 40.9)
    MarR; MarR family (PF01047; HMM-score: 38.5)
    and 9 more
    MarR_2; MarR family (PF12802; HMM-score: 29.1)
    HTH_20; Helix-turn-helix domain (PF12840; HMM-score: 17.8)
    TrmB; Sugar-specific transcriptional regulator TrmB (PF01978; HMM-score: 16.5)
    HTH_45; Winged helix-turn-helix (PF14947; HMM-score: 16.3)
    HTH_34; Winged helix DNA-binding domain (PF13601; HMM-score: 14.7)
    HTH_24; Winged helix-turn-helix DNA-binding (PF13412; HMM-score: 14.5)
    Replic_Relax; Replication-relaxation (PF13814; HMM-score: 14.3)
    HTH_IclR; IclR helix-turn-helix domain (PF09339; HMM-score: 14.2)
    Rrf2; Transcriptional regulator (PF02082; HMM-score: 14.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.001286
    • TAT(Tat/SPI): 0.000161
    • LIPO(Sec/SPII): 0.000316
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MLSQEFFNSFITIYRPYLKLAEPILEKHNIYYGQWLILRDIAKHQPTTLIEISHRRAIEKPTARKTLKALIENDLITVENSLEDKRQKFLTLTPKGHELYEIVCLDVQKLQQAVVAKTNISQDQMQETINVMNQIHEILLREAHND

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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