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NCBI: 02-MAR-2017
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus USA300_FPR3757
- locus tag: SAUSA300_RS12230 [old locus tag: SAUSA300_2216 ]
- pan locus tag?: SAUPAN005722000
- symbol: SAUSA300_RS12230
- pan gene symbol?: —
- synonym:
- product: MarR family transcriptional regulator
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SAUSA300_RS12230 [old locus tag: SAUSA300_2216 ]
- symbol: SAUSA300_RS12230
- product: MarR family transcriptional regulator
- replicon: chromosome
- strand: +
- coordinates: 2386471..2386911
- length: 441
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
- Location: NC_007793 (2386471..2386911) NCBI
- BioCyc: SAUSA300_RS12230 BioCyc
- MicrobesOnline: see SAUSA300_2216
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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421ATGCTATCACAAGAATTTTTCAATAGTTTTATAACAATATATCGCCCCTATTTAAAATTA
GCCGAGCCGATTTTAGAAAAACACAATATATATTATGGCCAATGGTTAATCTTACGCGAT
ATCGCTAAACATCAGCCCACTACTCTCATTGAAATTTCACATAGACGTGCAATTGAAAAG
CCTACTGCAAGAAAAACTTTAAAAGCTCTAATAGAAAATGACCTTATAACAGTAGAAAAC
AGTTTAGAGGATAAACGACAAAAGTTTTTAACTTTAACACCTAAAGGGCATGAATTATAT
GAGATTGTTTGTCTTGATGTACAAAAGCTCCAACAAGCAGTAGTTGCCAAAACAAACATT
TCGCAAGATCAAATGCAAGAAACCATAAATGTGATGAATCAAATTCATGAAATATTATTA
AGGGAGGCACACAATGACTAA60
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441
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SAUSA300_RS12230 [old locus tag: SAUSA300_2216 ]
- symbol: SAUSA300_RS12230
- description: MarR family transcriptional regulator
- length: 146
- theoretical pI: 7.16214
- theoretical MW: 17179.8
- GRAVY: -0.372603
⊟Function[edit | edit source]
- TIGRFAM: homoprotocatechuate degradation operon regulator, HpaR (TIGR02337; HMM-score: 50.4)and 4 moreRegulatory functions DNA interactions staphylococcal accessory regulator family (TIGR01889; HMM-score: 17)EPS-associated transcriptional regulator, MarR family (TIGR04176; HMM-score: 13.1)Regulatory functions DNA interactions beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family (TIGR02431; HMM-score: 12.7)putative choline sulfate-utilization transcription factor (TIGR03418; HMM-score: 12.2)
- TheSEED: see SAUSA300_2216
- PFAM: HTH (CL0123) HTH_27; Winged helix DNA-binding domain (PF13463; HMM-score: 40.9)MarR; MarR family (PF01047; HMM-score: 38.5)and 9 moreMarR_2; MarR family (PF12802; HMM-score: 29.1)HTH_20; Helix-turn-helix domain (PF12840; HMM-score: 17.8)TrmB; Sugar-specific transcriptional regulator TrmB (PF01978; HMM-score: 16.5)HTH_45; Winged helix-turn-helix (PF14947; HMM-score: 16.3)HTH_34; Winged helix DNA-binding domain (PF13601; HMM-score: 14.7)HTH_24; Winged helix-turn-helix DNA-binding (PF13412; HMM-score: 14.5)Replic_Relax; Replication-relaxation (PF13814; HMM-score: 14.3)HTH_IclR; IclR helix-turn-helix domain (PF09339; HMM-score: 14.2)Rrf2; Transcriptional regulator (PF02082; HMM-score: 14.1)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 7.5
- Cytoplasmic Membrane Score: 1.15
- Cellwall Score: 0.62
- Extracellular Score: 0.73
- Internal Helices: 0
- LocateP:
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.001286
- TAT(Tat/SPI): 0.000161
- LIPO(Sec/SPII): 0.000316
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
- GI: 446873803 NCBI
- RefSeq: WP_000951059 NCBI
- UniProt: see SAUSA300_2216
⊟Protein sequence[edit | edit source]
- MLSQEFFNSFITIYRPYLKLAEPILEKHNIYYGQWLILRDIAKHQPTTLIEISHRRAIEKPTARKTLKALIENDLITVENSLEDKRQKFLTLTPKGHELYEIVCLDVQKLQQAVVAKTNISQDQMQETINVMNQIHEILLREAHND
⊟Experimental data[edit | edit source]
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
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