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NCBI: 02-MAR-2017
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus USA300_FPR3757
- locus tag: SAUSA300_RS08740 [old locus tag: SAUSA300_1605 ]
- pan locus tag?: SAUPAN004255000
- symbol: SAUSA300_RS08740
- pan gene symbol?: mreC
- synonym:
- product: rod shape-determining protein MreC
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SAUSA300_RS08740 [old locus tag: SAUSA300_1605 ]
- symbol: SAUSA300_RS08740
- product: rod shape-determining protein MreC
- replicon: chromosome
- strand: -
- coordinates: 1756995..1757837
- length: 843
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
- Location: NC_007793 (1756995..1757837) NCBI
- BioCyc: SAUSA300_RS08740 BioCyc
- MicrobesOnline: see SAUSA300_1605
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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841GTGCTTAAGTTTTTTAAAAATAACAAATTAATTGTTGTTTTATGTGCAATTATCGTTTTT
ATTGCATTAATTGGGCTGTCCATACGTTCACAATCTCAATCACCTCCTGAACAATATATA
GGTGATTCTGTGTCTTTTGGACAACGAGTTGTGAGTTATCCAGTTAATTTTGTTGCTGGT
ACGATTGGGGACTTTTTTAAAAAAGGAGATTCTAAAGAATCTAAAAATAAGATTAGCCAG
TTAGAATCTAAGAACCAACAATTAGAAGCGGAAAATGAAAAATTAAAAAAAGAGCTTGAT
TTAAAAGATATTTCAAAATTTGATCCTATTTCTACTACGGTTTTGGCAAGAAATCCGGAT
CAGTGGATGAATACAATTGTAATTGATAAGGGATCTAAATCAGGTATAACTTCAAATATG
GCTGTGATGACATCACAAGGTTTTGTTGGAAGAGTTACTAAAGTTAATAAATTTTCTTCA
CAAGTTGATTTAATCTCAACTAATACACGTGCGGGTAAATTATCTGTAAATATACAACAC
GGTTCTAAAAATATATTTGGTTTAATTGATCGTTATGATGAAAAGAACTCAGAACTTGTA
ATTAGTGACATTAATAATAGAGATAATATCTCAAAAGGTGATAAAGTCGTTACAAGTGGA
TTAGCTGATCAACTACCAAGTAATTTATATATAGGAGAAGTGACTAAGGTTCAAAATGAT
CAATACGGCTTAGCTAAAGAAGTTAGGGTTAAGACTGGTGCGGACTTAACAGATTTGAGT
CATGTTTATGTTGCAAAAAGAGATCCTAAAACAATTCCTGATGATGAAAGCAGGGATAAA
TAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SAUSA300_RS08740 [old locus tag: SAUSA300_1605 ]
- symbol: SAUSA300_RS08740
- description: rod shape-determining protein MreC
- length: 280
- theoretical pI: 9.59859
- theoretical MW: 31010
- GRAVY: -0.398929
⊟Function[edit | edit source]
- TIGRFAM: Cell envelope Biosynthesis and degradation of murein sacculus and peptidoglycan rod shape-determining protein MreC (TIGR00219; HMM-score: 147)and 4 moreMobile and extrachromosomal element functions Plasmid functions integrating conjugative element protein, PFL_4705 family (TIGR03752; HMM-score: 18.1)Protein fate Protein and peptide secretion and trafficking preprotein translocase, YajC subunit (TIGR00739; HMM-score: 15)integrating conjugative element protein, PFL_4669 family (TIGR03761; HMM-score: 12.1)Cellular processes Cell division cell division protein FtsL (TIGR02209; HMM-score: 4.9)
- TheSEED: see SAUSA300_1605
- PFAM: no clan defined MreC; rod shape-determining protein MreC (PF04085; HMM-score: 135.4)and 12 moreYajC; Preprotein translocase subunit (PF02699; HMM-score: 22.5)TSC22; TSC-22/dip/bun family (PF01166; HMM-score: 18.7)FtsL (CL0225) DivIC; Septum formation initiator (PF04977; HMM-score: 17.4)no clan defined YabB; Initiation control protein YabA (PF06156; HMM-score: 16.6)IncA; IncA protein (PF04156; HMM-score: 15.4)OppC_N; N-terminal TM domain of oligopeptide transport permease C (PF12911; HMM-score: 15.2)DUF1845; Domain of unknown function (DUF1845) (PF08900; HMM-score: 15.1)bZIP (CL0018) bZIP_1; bZIP transcription factor (PF00170; HMM-score: 15)no clan defined Kinetocho_Slk19; Central kinetochore-associated (PF12709; HMM-score: 14.7)bZIP (CL0018) bZIP_2; Basic region leucine zipper (PF07716; HMM-score: 14.5)no clan defined Swi5; Swi5 (PF07061; HMM-score: 12.8)Shugoshin_N; Shugoshin N-terminal coiled-coil region (PF07558; HMM-score: 7.2)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: unknown (no significant prediction)
- Cytoplasmic Score: 0
- Cytoplasmic Membrane Score: 3.33
- Cellwall Score: 3.33
- Extracellular Score: 3.33
- Internal Helix: 1
- LocateP:
- SignalP: Signal peptide SP(Sec/SPI) length 32 aa
- SP(Sec/SPI): 0.795076
- TAT(Tat/SPI): 0.001816
- LIPO(Sec/SPII): 0.137729
- Cleavage Site: CS pos: 32-33. SQS-QS. Pr: 0.5493
- predicted transmembrane helices (TMHMM): 1
⊟Accession numbers[edit | edit source]
- GI: 446833785 NCBI
- RefSeq: WP_000911041 NCBI
- UniProt: see SAUSA300_1605
⊟Protein sequence[edit | edit source]
- MLKFFKNNKLIVVLCAIIVFIALIGLSIRSQSQSPPEQYIGDSVSFGQRVVSYPVNFVAGTIGDFFKKGDSKESKNKISQLESKNQQLEAENEKLKKELDLKDISKFDPISTTVLARNPDQWMNTIVIDKGSKSGITSNMAVMTSQGFVGRVTKVNKFSSQVDLISTNTRAGKLSVNIQHGSKNIFGLIDRYDEKNSELVISDINNRDNISKGDKVVTSGLADQLPSNLYIGEVTKVQNDQYGLAKEVRVKTGADLTDLSHVYVAKRDPKTIPDDESRDK
⊟Experimental data[edit | edit source]
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
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