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NCBI: 26-AUG-2013

Summary[edit source | edit]

  • organism: Staphylococcus aureus N315
  • locus tag: SA1302 [new locus tag: SA_RS07365 ]
  • pan locus tag?: SAUPAN003930000
  • symbol: gerCC
  • pan gene symbol?: hepT
  • synonym:
  • product: heptaprenyl diphosphate syntase component II

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SA1302 [new locus tag: SA_RS07365 ]
  • symbol: gerCC
  • product: heptaprenyl diphosphate syntase component II
  • replicon: chromosome
  • strand: -
  • coordinates: 1508018..1508977
  • length: 960
  • essential: no DEG other strains

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    GTGGCAAAGTTAAACATGAACAATGAAATTAAGAAAGTGGAACAACGACTTGAAAAGGCA
    ATAAAAAGTAAAGATTCTGTATTAGAACAGGCATCATTACACTTATTGTCTTCTGGTGGT
    AAAAGAGTACGCCCAGCATTTGTTATTCTGAGTAGCCAATTTGGCAAAGATGAACAAACG
    TCTGAACAAACGTATCAAGTTGCAGTCGCATTAGAGTTAATTCATATGGCAACACTTGTT
    CATGATGACGTTATTGATAAAAGCGACAAGCGTCGAGGCAAGTTAACCATATCAAAGAAA
    TGGGATCAGACAACTGCTATTTTAACTGGGAATTTTTTATTGGCATTAGGACTTGAACAC
    TTAATGGCCGTTAAAGATAATCGTGTACATCAATTGATATCTGAATCTATCGTTGATGTT
    TGTAGAGGGGAACTTTTCCAATTTCAAGACCAATTTAACAGTCAACAGACAATTATTAAT
    TATTTACGACGTATCAATCGCAAAACAGCACTGTTAATTCAAATATCAACTGAAGTTGGT
    GCAATTACTTCTCAATCTGATAAAGAGACTGTACGAAAATTGAAAATGATTGGTCATTAT
    ATAGGTATGAGCTTCCAAATCATTGATGATGTATTAGACTTCACAAGTACCGAAAAGAAA
    TTAGGTAAGCCGGTCGGAAGTGATTTGCTTAATGGTCATATTACGTTACCGATTTTATTA
    GAAATGCGTAAAAATCCAGACTTCAAATTGAAAATCGAACAGTTACGTCGTGATAGTGAA
    CGCAAAGAATTTGAAGAATGTATCCAAATCATTAGAAAATCTGACAGCATCGATGAGGCT
    AAGGCAGTAAGTTCGAAGTATTTAAGTAAAGCTTTGAATTTGATTTCTGAGTTACCAGAT
    GGACATCCGAAATCACTACTTTTAAGTTTGACGAAAAAAATGGGGTCAAGAAACACATAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SA1302 [new locus tag: SA_RS07365 ]
  • symbol: GerCC
  • description: heptaprenyl diphosphate syntase component II
  • length: 319
  • theoretical pI: 9.89584
  • theoretical MW: 36142.6
  • GRAVY: -0.351411

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    MetabolismBiosynthesis of cofactors, prosthetic groups, and carriersMenaquinone and ubiquinoneheptaprenyl diphosphate synthase component II (TIGR02748; EC 2.5.1.30; HMM-score: 378.6)
    MetabolismBiosynthesis of cofactors, prosthetic groups, and carriersMenaquinone and ubiquinonesolanesyl diphosphate synthase (TIGR02749; EC 2.5.1.-; HMM-score: 242.5)
  • TheSEED:  
    Fatty Acids, Lipids, and IsoprenoidsIsoprenoidsIsoprenoid scratch Heptaprenyl diphosphate synthase component II (EC 2.5.1.30) 
    IsoprenoidsIsoprenoinds for Quinones Heptaprenyl diphosphate synthase component II (EC 2.5.1.30) 
    IsoprenoidsPolyprenyl Diphosphate Biosynthesis Heptaprenyl diphosphate synthase component II (EC 2.5.1.30) 
    Regulation and Cell signalingRegulation and Cell signaling - no subcategorySex pheromones in Enterococcus faecalis and other Firmicutes Heptaprenyl diphosphate synthase component II (EC 2.5.1.30) 
  • PFAM:
    Terp_synthase (CL0613) polyprenyl_synt; Polyprenyl synthetase (PF00348; HMM-score: 222.7)
    HEPPP_synt_1; Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 (PF07307; HMM-score: 29.4)
    no clan definedBaculo_p33; Baculovirus P33 (PF05214; HMM-score: 16.5)
    NADP_Rossmann (CL0063) Pyr_redox_3; Pyridine nucleotide-disulphide oxidoreductase (PF13738; HMM-score: 15.2)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular Possibility: 1
    • Signal Peptide Possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • Ymax: 0.161
    • Ymax_pos: 17
    • Cmax: 0.139
    • Cmax_pos: 61
    • Smax: 0.312
    • Smax_pos: 10
    • Smean: 0.24
    • D: 0.192
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

  • GI: 15927051 NCBI
  • RefSeq: NP_374584 NCBI
  • UniProt:

Protein sequence[edit source | edit]

  • MAKLNMNNEIKKVEQRLEKAIKSKDSVLEQASLHLLSSGGKRVRPAFVILSSQFGKDEQTSEQTYQVAVALELIHMATLVHDDVIDKSDKRRGKLTISKKWDQTTAILTGNFLLALGLEHLMAVKDNRVHQLISESIVDVCRGELFQFQDQFNSQQTIINYLRRINRKTALLIQISTEVGAITSQSDKETVRKLKMIGHYIGMSFQIIDDVLDFTSTEKKLGKPVGSDLLNGHITLPILLEMRKNPDFKLKIEQLRRDSERKEFEECIQIIRKSDSIDEAKAVSSKYLSKALNLISELPDGHPKSLLLSLTKKMGSRNT

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]