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PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 03-AUG-2016

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus NCTC8325
  • locus tag: SAOUHSC_01538
  • pan locus tag?: SAUPAN001834000
  • symbol: SAOUHSC_01538
  • pan gene symbol?: —
  • synonym:
  • product: phage terminase large subunit

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SAOUHSC_01538
  • symbol: SAOUHSC_01538
  • product: phage terminase large subunit
  • replicon: chromosome
  • strand: -
  • coordinates: 1486012..1487703
  • length: 1692
  • essential: no DEG

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    GTGACTATTAAAGTTTTAAATGAACCTTCACCAAAACTATTAACAACATGGTATGCAGAG
    CAAGTCACTCAAGGGAAAATAAAAACAAGCAAATATGTTAAAAAAGAATGTGAGAGACAC
    CTTAGATATCTAGAAAATGGAGGTAAATGGGTATTTGATGAAGAATTAGCGCACCGTCCT
    ATTCGATTCATAGAAAAGTTTTGTAAACCTTCCAAAGGATCTAAACGTCAACTTGTATTA
    CAACCATGGCAACATTTTATTATTGGCAGTTTGTTTGGTTGGGTTCATAAAGAAACAAAA
    CTGCGCAGGTTTAAAGAAGCTTTGATATTTATGGGGCGAAAAAATGGTAAAACAACTACT
    ATATCTGGTGTTGCTAACTATGCTGTTTCTCAAGATGGAGAAAACGGCGCTGAAATCCAT
    CTTTTAGCAAACGTAATGAAACAAGCTAGGATTCTATTTGATGAATCTAAGGCGATGATT
    AAAGCTAGCCCAAAGCTTAGAGAAAATTTTAGACCTTTGAGAGATGAAATTCATTACGAT
    GCAACTATATCTAAAATTATGCCACAGGCTTCAGACAGTGATAAGTTGGATGGTTTAAAT
    ACACATATGGGCATTTTTGATGAAATTCATGAATTTAAAGATTATAAATTGATTTCAGTT
    ATAAAAAACTCAAGAGCGGCAAGGTTACAACCCCTTCTTATCTACATTACGACAGCAGGG
    TACCAACTAGATGGACCACTTGTTAATATGGTAGAAGCGGGAAGAGACACCTTAGATCGA
    ATCATCGAAGATGAAAGAACTTTTTACTATTTAGCTTCTCTCGATGATGACGATGATATA
    AATGATTCGTCGAATTGGATTAAAGCAAATCCTAACCTAGGTGTTTCTATCGATTTAGCT
    GAAATGAAAGAAGAGTGGGAAAAGGCTAAGAGAACACCAGATGAACGTGGAGATTTTATA
    ACCAAAAGGTTTAACATCTTTGCTAATAATGATGAGATGAGTTTTATTGATTATCCAACA
    CTTCAAAAAAATAATGACATTATTTCCTTAGATGAGTTGGAAGGTAGACCATGTACTATA
    GGTTATGATTTATCAGAAACAGAGGACTTTACAGCCGCATGTGCCACTTTTGCATTAGAT
    AATGGCAAAGTTGCTGTCTTAACACATTCTTGGATTCCTAAGCATAAAGTTGAATATTCT
    AACGAAAAGATACCCTATATAGAATGGGAAGAAGACGGATTACTAACAATACAAGATAAT
    CCTTATATAGACTACCAAGATGTTTTAAATTGGATAATAAAGATGAATGAGCATTATGTT
    GTCGAAAAAATCACTTATGATAGGGCGAATGCTTTTAAATTAAATCAAGAGTTAAAGAAT
    TATGGCTTTGAAACAGAAGAAACAAGACAAGGGGCTTTGACCTTGAGCCCTGCATTGAAG
    GATCTAAAAGAAATGTTTTTAGATGGGAAAATAATATTTAATAATAATCCTTTAATGAAA
    TGGTATATCAATAATGTTCAGCTGAAACTAGACAGAAATGGGAACTGGCTGCCATCTAAA
    CAAAGCAGATATCGTAAAATAGATGGTTTTGCAGCATTTTTAAACACATATACAGATATT
    ATGAATAAAGTTGTTTCTGACAAGGGTGAAGGAAACATAGAATTTATTAGTATTAAAGAT
    ATAATGCGTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1692

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SAOUHSC_01538
  • symbol: SAOUHSC_01538
  • description: phage terminase large subunit
  • length: 563
  • theoretical pI: 6.0331
  • theoretical MW: 65246.9
  • GRAVY: -0.54103

⊟Function[edit | edit source]

  • TIGRFAM:
  • TheSEED  :
    • Phage terminase large subunit
  • PFAM:
    P-loop_NTPase (CL0023) Terminase_1; Phage Terminase (PF03354; HMM-score: 264.3)
    and 3 more
    no clan defined Tail_tube; Phage tail tube protein (PF10618; HMM-score: 13.8)
    CagD; Pathogenicity island component CagD (PF16567; HMM-score: 13.2)
    COP23; Circadian oscillating protein COP23 (PF14218; HMM-score: 12.5)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.011278
    • TAT(Tat/SPI): 0.000308
    • LIPO(Sec/SPII): 0.003165
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MTIKVLNEPSPKLLTTWYAEQVTQGKIKTSKYVKKECERHLRYLENGGKWVFDEELAHRPIRFIEKFCKPSKGSKRQLVLQPWQHFIIGSLFGWVHKETKLRRFKEALIFMGRKNGKTTTISGVANYAVSQDGENGAEIHLLANVMKQARILFDESKAMIKASPKLRENFRPLRDEIHYDATISKIMPQASDSDKLDGLNTHMGIFDEIHEFKDYKLISVIKNSRAARLQPLLIYITTAGYQLDGPLVNMVEAGRDTLDRIIEDERTFYYLASLDDDDDINDSSNWIKANPNLGVSIDLAEMKEEWEKAKRTPDERGDFITKRFNIFANNDEMSFIDYPTLQKNNDIISLDELEGRPCTIGYDLSETEDFTAACATFALDNGKVAVLTHSWIPKHKVEYSNEKIPYIEWEEDGLLTIQDNPYIDYQDVLNWIIKMNEHYVVEKITYDRANAFKLNQELKNYGFETEETRQGALTLSPALKDLKEMFLDGKIIFNNNPLMKWYINNVQLKLDRNGNWLPSKQSRYRKIDGFAAFLNTYTDIMNKVVSDKGEGNIEFISIKDIMR

⊟Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Ulrike Mäder, Pierre Nicolas, Maren Depke, Jan Pané-Farré, Michel Debarbouille, Magdalena M van der Kooi-Pol, Cyprien Guérin, Sandra Dérozier, Aurelia Hiron, Hanne Jarmer, Aurélie Leduc, Stephan Michalik, Ewoud Reilman, Marc Schaffer, Frank Schmidt, Philippe Bessières, Philippe Noirot, Michael Hecker, Tarek Msadek, Uwe Völker, Jan Maarten van Dijl
    Staphylococcus aureus Transcriptome Architecture: From Laboratory to Infection-Mimicking Conditions.
    PLoS Genet: 2016, 12(4);e1005962
    [PubMed:27035918] [WorldCat.org] [DOI] (I e)

⊟Relevant publications[edit | edit source]

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