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NCBI: 10-JUN-2013
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus USA300_FPR3757
- locus tag: SAUSA300_0219 [new locus tag: SAUSA300_RS01150 ]
- pan locus tag?: SAUPAN001079000
- symbol: SAUSA300_0219
- pan gene symbol?: hptA
- synonym:
- product: putative iron compound A C transporter, iron compound-binding protein
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SAUSA300_0219 [new locus tag: SAUSA300_RS01150 ]
- symbol: SAUSA300_0219
- product: putative iron compound A C transporter, iron compound-binding protein
- replicon: chromosome
- strand: -
- coordinates: 259023..259991
- length: 969
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
- Gene ID: 3914159 NCBI
- RefSeq: YP_492933 NCBI
- BioCyc: see SAUSA300_RS01150
- MicrobesOnline: 1291734 MicrobesOnline
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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961ATGAAATCAAAAATTTATATCTTGCTATTATTTCTCATTTTTTTATCAGCATGCGCTAAT
ACGCGTCACTCTGAATCCGATAAAAATGTATTAACAGTTTATTCTCCGTATCAATCAAAC
TTGATTCGTCCAATTTTAAATGAATTTGAAAAACAAGAGCATGTCAAAATTGAAATTAAA
CACGGATCTACTCAAGTACTGCTTTCAAACTTGCATAACGAAGATTTTTCGGAGCGTGGT
GATGTCTTTATGGGTGGTGTGTTGTCAGAAACAATTGATCATCCAGAAGATTTTGTTCCC
TATCAAGATACATCTGTAACACAGCAATTAGAGGATTATCGCTCGAACAATAAATATGTT
ACTAGTTTTCTATTAATGCCAACAGTTATAGTAGTGAATTCAGATTTACAAGGAGATATT
AAGATTCGAGGTTATCAAGATTTATTACAACCTATACTTAAAGGTAAAATTGCGTACTCA
AATCCAAATACAACAACGACAGGCTATCAACATATGCGTGCTATTTATAGCATGCATCAT
CGAGTAAGTGATGTGCATCAATTCCAAAACCATGCGATGCAACTGTCAAAGACGTCTAAA
GTCATTGAAGATGTTGCAAAAGGTAAATATTACGCAGGTCTAAGCTACGAACAAGATGCA
CGCACATGGAAAAACAAAGGTTATCCTGTATCAATCGTTTATCCAATTGAAGGAACAATG
TTAAATGTTGATGGTATTGCTTTAGTTAAAAATGCACACCCTCATCCTAAGCGTAAAAAG
TTAGTGCAATATTTAACAAGCCGCTCAGTACAACAACGATTAGTTGCAGAGTTCGATGCC
AAGTCAATTCGAAAGGATGTTAGTGAACAAAGCGATCAGTCTATCGAAAATCTTAAGAAC
ATACCTTTAATACCGAAATCTAAATTACCGGATATTCCACATCATAAATTTTTGGAGATG
ATTCAATGA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SAUSA300_0219 [new locus tag: SAUSA300_RS01150 ]
- symbol: SAUSA300_0219
- description: putative iron compound A C transporter, iron compound-binding protein
- length: 322
- theoretical pI: 8.99606
- theoretical MW: 36931.9
- GRAVY: -0.455279
⊟Function[edit | edit source]
- TIGRFAM: Transport and binding proteins Amino acids, peptides and amines putative 2-aminoethylphosphonate ABC transporter, periplasmic 2-aminoethylphosphonate-binding protein (TIGR03261; HMM-score: 88.7)and 2 more2-aminoethylphosphonate ABC transporter, 2-aminoethylphosphonate binding protein (TIGR03227; HMM-score: 40.9)Transport and binding proteins Other ABC transporter periplasmic binding protein, thiB subfamily (TIGR01254; HMM-score: 27.2)
- TheSEED :
- Ferric iron ABC transporter, iron-binding protein
- PFAM: PBP (CL0177) SBP_bac_11; Bacterial extracellular solute-binding protein (PF13531; HMM-score: 74.7)SBP_bac_6; Bacterial extracellular solute-binding protein (PF13343; HMM-score: 62.9)and 3 moreSBP_bac_8; Bacterial extracellular solute-binding protein (PF13416; HMM-score: 38.7)SBP_bac_1; Bacterial extracellular solute-binding protein (PF01547; HMM-score: 23.1)LppaM (CL0421) LPAM_1; Prokaryotic membrane lipoprotein lipid attachment site (PF08139; HMM-score: 12.5)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic Membrane
- Cytoplasmic Score: 0.32
- Cytoplasmic Membrane Score: 9.55
- Cellwall Score: 0.12
- Extracellular Score: 0.01
- Internal Helices: 0
- LocateP: Lipid anchored
- Prediction by SwissProt Classification: Extracellular
- Pathway Prediction: Sec-(SPII)
- Intracellular possibility: -0.33
- Signal peptide possibility: 1
- N-terminally Anchored Score: 1
- Predicted Cleavage Site: FLSACAN
- SignalP: Signal peptide LIPO(Sec/SPII) length 17 aa
- SP(Sec/SPI): 0.001198
- TAT(Tat/SPI): 0.000118
- LIPO(Sec/SPII): 0.998256
- Cleavage Site: CS pos: 17-18. LSA-CA. Pr: 0.9990
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MKSKIYILLLFLIFLSACANTRHSESDKNVLTVYSPYQSNLIRPILNEFEKQEHVKIEIKHGSTQVLLSNLHNEDFSERGDVFMGGVLSETIDHPEDFVPYQDTSVTQQLEDYRSNNKYVTSFLLMPTVIVVNSDLQGDIKIRGYQDLLQPILKGKIAYSNPNTTTTGYQHMRAIYSMHHRVSDVHQFQNHAMQLSKTSKVIEDVAKGKYYAGLSYEQDARTWKNKGYPVSIVYPIEGTMLNVDGIALVKNAHPHPKRKKLVQYLTSRSVQQRLVAEFDAKSIRKDVSEQSDQSIENLKNIPLIPKSKLPDIPHHKFLEMIQ
⊟Experimental data[edit | edit source]
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You are kindly invited to share additional interesting facts.
⊟Literature[edit | edit source]
⊟References[edit | edit source]
⊟Relevant publications[edit | edit source]
Joo Youn Park, Jong Wan Kim, Bo Youn Moon, Juyeun Lee, Ye Ji Fortin, Frank W Austin, Soo-Jin Yang, Keun Seok Seo
Characterization of a novel two-component regulatory system, HptRS, the regulator for the hexose phosphate transport system in Staphylococcus aureus.
Infect Immun: 2015, 83(4);1620-8
[PubMed:25644013] [WorldCat.org] [DOI] (I p)